Gene Information

Name : polI (SGO_0145)
Accession : YP_001449466.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 152698 - 155340 bp
Length : 2643 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAAAAAAGAACAAATTATTATTAATCGACGGTTCGTCCGTTGCTTTTCGCGCTTTTTTTGCGCTTTATAATCAAAT
CGACCGTTTCAAGAGTCCATCGGGCCTGCATACCAATGCCATTTATGGCTTCCACCTCATGCTCAATCATCTCTTGGAGC
GCGTGCAGCCGACTCATGTCCTGGTAGCTTTTGATGCCGGTAAGACGACCTTTCGGACCGAGATGTACGCCGACTATAAG
GCTGGCCGGGCCAAGACACCGGATGAATTTCGGGAGCAGCTGCCCTTTATCCGAGAAATGCTACAGCACCTAGGCATTCA
CTACTACGATTTGGCTCAATACGAGGCGGATGACATCATCGGGACCTTGGACAAGATGGCTGAAAAGACAGCTGTGCCTT
ACGATGTGACCATTGTCAGCGGCGATAAAGACTTGATTCAGCTGACGGATGATAATACCGTGGTGGAGATTTCCAAGAAA
GGCGTGGCCGAGTTCGAAGAATTTACCCCAGCCTACCTCATGGAAAAGATGGGCATCACGCCAGAGCAGTTCATTGACCT
CAAGGCGCTGATGGGCGATCAATCGGACAATATCCCCGGTGTGACTAAGATCGGTGAGAAGACTGGCCTCAAGCTCCTCT
TGGAGTATGGCTCTTTGGAAAATCTCTATGAAAACATTGACCAGCTCAAGGCTTCCAAGATGAAGGAAAACCTAATTAAT
GACAAGGACAAGGCCTTCTTATCAAAAACCTTAGCCACTATCAATACTCAGGCTCCGATTGAAATCGGGCTAGATGATTT
GGTTTATAAGGGTCCGCAGGTAGAGGCACTGAGCAAGTTCTACGACGAGATGGGCTTCAAGCAACTCAAAGCTCAGCTAG
GAACTACTCAGGAGCCAGTAGAAGTCAAACCAATTGAATTTACCAAAGTGACTGAGGTGACAGCAGATATGCTGGGACCA
GAGCAATTCTTCTATTTTGAAATTTTGGGTGACAACTACCACAGGGAAGAGATTGTCGGTCTTGCCTGGGGTGATAGCCG
TCAGATTTATGTCGGTTCCAGCGATTTACTGCAGCAGCCTCTCTTTCAGGAGTTCTTGACAAAAACAGCTCTGAAAACCT
ACGACCTCAAGCGGGCCAAGGTACTGCTCAGTCATTACGGCATTGAACTGCCAGCAGCAACCTTTGATGCGCGCCTAGCC
AAGTATCTGCTTTCGACGGTCGAGGATAATGAGCTGGCGACTATTGCTCGCCTCTACGGCCAAACAATCCTGCCAACTGA
TGATGAGGTTTATGGCAAGGGGGCCAAGCGTGCTCTGCCAGAGCAAGAGCAGCTCTTTGAGCATCTGGCTCGTAAGGTTC
AGGTACTGTTGGAAACTGAAGAGCCGATGCAAGAGCAACTTCGTTCCCACGATCAACTGGATTTGTTGTTTGAAATGGAG
CAGCCGCTGGCCTTTGTCCTAGCCAAGATGGAGATTGCGGGGATTAAGGTTGAGCGGGAAACCCTGCAGGGCATGCAGGC
GGAAAATGAAAAGACGCTGGAAAGCCTGACTCAGGAGATTTATGATCTGGCTGGTCAGGAGTTCAATATCAACTCACCGA
AACAGCTGGGGACCATTCTTTTTGAGGATATGGGACTGCCACTGGAGTACACCAAAAAGACCAAGACAGGTTACTCGACA
GCGGTTGATGTGCTGGAGCGCCTAGCTCCCATTGCACCGATTGTGTCTAAGATTCTGGAATACCGTCAAATCAGCAAGCT
CCAGTCCACTTATATCATCGGACTGCAGGAGGCGATTGCGGCTGACGGTAAGATTCACACTCGCTATGTTCAGGATTTGA
CTCAGACTGGCCGCCTGTCCTCGGTTGACCCGAACCTGCAGAATATCCCCGTTCGTTTGGAGCAGGGGCGCCTCATTCGC
AAGGCATTTGTACCGGAGTGGGCAGACAGTGTGCTTCTCAGCTCGGATTATTCCCAGATTGAGCTGCGGGTGCTGGCTCA
TATTTCGCAGGACGAGCATCTGATTGCTGCCTTTCAGCATGGAGAAGACATTCACACGGCTACAGCCATGCGGGTCTTTG
GTATTGAAAAGGCAGAGGATGTGACACCTAATGACCGCCGTAATGCCAAGGCCGTCAACTTTGGAGTGGTCTATGGCATT
TCCGACTTTGGCCTAGCCAATAATCTGGGCATTTCCCGCAAGGCTGCTAAGGACTATATCCAGACCTATTTTGAGCGTTT
CCCTGGTATCAAGAATTATATGGAAACCATCGTTCGCGAAGCGCGTGATAAGGGCTATGTAGAGACCATTTACCATCGCC
GTCGCTCCTTGCCGGACATCAATTCCCGCAACTTTAACATCCGAAATTTTGCGGAGCGCACAGCCATTAACAGCCCCATC
CAAGGATCGGCCGCAGATATTCTCAAAGTCGCTATGATTAATCTGGATCGAGCTCTGACAGAGAAGAATTTCAAGTCGCG
CATGCTCTTGCAGGTGCACGATGAAATTGTGTTAGAAGTGCCAAATGACGAGCTAACAGCCGTCCGCCAGCTAGTCAAAG
AAACCATGGAAGCCGCGATTGAACTGGCAGTTCCACTAGTAGCAGATGAAAACGCCGGCCAAACTTGGTACGAGGCAAAA
TAA

Protein sequence :
MEKKNKLLLIDGSSVAFRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHVLVAFDAGKTTFRTEMYADYK
AGRAKTPDEFREQLPFIREMLQHLGIHYYDLAQYEADDIIGTLDKMAEKTAVPYDVTIVSGDKDLIQLTDDNTVVEISKK
GVAEFEEFTPAYLMEKMGITPEQFIDLKALMGDQSDNIPGVTKIGEKTGLKLLLEYGSLENLYENIDQLKASKMKENLIN
DKDKAFLSKTLATINTQAPIEIGLDDLVYKGPQVEALSKFYDEMGFKQLKAQLGTTQEPVEVKPIEFTKVTEVTADMLGP
EQFFYFEILGDNYHREEIVGLAWGDSRQIYVGSSDLLQQPLFQEFLTKTALKTYDLKRAKVLLSHYGIELPAATFDARLA
KYLLSTVEDNELATIARLYGQTILPTDDEVYGKGAKRALPEQEQLFEHLARKVQVLLETEEPMQEQLRSHDQLDLLFEME
QPLAFVLAKMEIAGIKVERETLQGMQAENEKTLESLTQEIYDLAGQEFNINSPKQLGTILFEDMGLPLEYTKKTKTGYST
AVDVLERLAPIAPIVSKILEYRQISKLQSTYIIGLQEAIAADGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIR
KAFVPEWADSVLLSSDYSQIELRVLAHISQDEHLIAAFQHGEDIHTATAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGI
SDFGLANNLGISRKAAKDYIQTYFERFPGIKNYMETIVREARDKGYVETIYHRRRSLPDINSRNFNIRNFAERTAINSPI
QGSAADILKVAMINLDRALTEKNFKSRMLLQVHDEIVLEVPNDELTAVRQLVKETMEAAIELAVPLVADENAGQTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 76