Gene Information

Name : pyk (SGO_1339)
Accession : YP_001450620.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1382812 - 1384317 bp
Length : 1506 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAACAAACGCGTAAAAATTGTTGCAACACTAGGTCCAGCGGTTGAAATCCGTGGTGGTAAAAAATTCGGTGAAGACGG
ATACTGGGGAGAAAAACTTGACGTTGAAGCTTCAGCTAAAAACATTGCTAAATTGATTGAAGCAGGAGCAAACACTTTCC
GTTTTAACTTCTCACACGGTGACCACCAAGAGCAAGGTGAACGCATGGCAACTGTTAAACTTGCTGAAGAAATTGCTGGT
CAAAAAGTTGGTTTCCTTCTTGATACTAAAGGACCTGAAATCCGTACAGAATTGTTTGAAGGTGACGCAAAAGAGTACTC
TTACAAAACTGGTGAAAAAATCCGTGTTGCAACTAAACAAGGTATCAAATCAACTCGTGATGTGATTGCTTTGAACGTTG
CTGGTGCCCTTGACATCTACGATGATGTTGAAGTTGGTCACCAAGTTTTGGTTGACGATGGTAAACTTGGTCTTCGTGTT
TTCGCAAAAGACGATGCAACTCGTGAATTTGAAGTAGTCGTTGAAAATGACGGTATCATTGCTAAGCAAAAAGGTGTAAA
CATCCCTAACACTAAAATTCCTTTCCCAGCACTTGCTGAGCGCGATAACGATGATATCCGTTTCGGTTTGGAACAAGGTA
TCAACTTCATCGCGATTTCATTTGTACGTACTGCAAAGGACGTTGACGAAGTTCGTGCTATCTGTGAAGAAACTGGTAAT
GGTCACGTTCAATTGTTTGCTAAAATCGAAAACCAACAAGGTATTGATAACTTGGACGAAATCATTGAAGCTGCTGACGG
TATTATGATTGCTCGTGGTGACATGGGTATTGAAGTACCATTTGAAATGGTTCCAGTTTACCAAAAAATGATCATCACTA
AAGTGAACGCAGCAGGTAAAGTTGTTATCACAGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT
TCAGAAGTATCAGACGTATTTAACGCTGTTATTGACGGTACTGACGCTACAATGCTTTCAGGTGAGTCTGCAAATGGTAA
ATACCCACTTGAGTCAGTAACAACAATGGCTACAATTGACAAGAATGCACAAACTCTTCTTAACGAATACGGACGTTTGA
ACTCAGATACTTTCGAACGTAATTCTAAAACAGAAGTTATGGCTTCAGCTGTTAAAGATGCTACTAACTCAATGGATATC
AAATTGGTAGTTACTCTTACTAAGACTGGACACACAGCCCGCTTGATCTCTAAATACCGTCCAAATGCTGATATCTTGGC
ATTGACATTTGACGAATTAACAGAGCGTGGATTGATGTTGAACTGGGGTGTTATCCCGATGTTGACAGACACTCCATCAT
CAACTGATGACATGTTTGAAATTGCTGAACGTAAAGCAGTTGAAGCAGGTCTTGTACAATCTGGTGATGATATCGTTATC
GTTGCTGGTGTACCAGTTGGAGAAGCTGTTCGTACAAACACAATGCGTATCCGCACAGTTCGCTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAKLIEAGANTFRFNFSHGDHQEQGERMATVKLAEEIAG
QKVGFLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTRDVIALNVAGALDIYDDVEVGHQVLVDDGKLGLRV
FAKDDATREFEVVVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVDEVRAICEETGN
GHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKVVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLNSDTFERNSKTEVMASAVKDATNSMDI
KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDTPSSTDDMFEIAERKAVEAGLVQSGDDIVI
VAGVPVGEAVRTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-80 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-80 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-80 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-81 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_001450620.1 pyruvate kinase VFG0479 Protein 1e-80 44