Gene Information

Name : lysS (SAHV_0514)
Accession : YP_001441104.1
Strain : Staphylococcus aureus Mu3
Genome accession: NC_009782
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 573265 - 574752 bp
Length : 1488 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCAGAAGAAATGAATGACCAAATGTTGGTTCGACGTCAAAAATTACAAGAATTATATGATCTTGGTATAGACCCGTT
TGGTTCTAAATTTGACCGTTCAGGTTTATCTAGTGATTTGAAAGAAGAGTGGGACCAGTATTCTAAAGAAGAATTGGTAG
AAAAAGAAGCGGATAGTCATGTCGCTATAGCTGGACGATTAATGACTAAGCGTGGTAAAGGTAAAGCAGGATTTGCACAC
GTTCAGGACTTAGCTGGACAAATTCAAATTTACGTTCGTAAAGATCAAGTTGGCGATGACGAATTTGATTTATGGAAAAA
TGCTGATTTAGGCGATATCGTTGGTGTTGAAGGTGTAATGTTCAAAACAAATACTGGCGAATTATCGGTTAAAGCGAAGA
AATTCACGCTACTAACTAAATCATTGCGACCATTACCGGATAAATTCCACGGTTTACAGGATATTGAACAGAGATATCGT
CAAAGATATTTAGATTTAATTACGAACGAAGATAGCACTCGTACATTTATTAATCGTAGTAAAATCATTCAAGAAATGCG
TAATTATTTAAATAATAAAGGTTTCTTGGAAGTAGAAACACCTATGATGCACCAAATTGCTGGTGGCGCAGCTGCTAGAC
CATTTGTAACACATCATAATGCATTAGATGCAACGTTATACATGCGTATTGCTATTGAGTTGCATTTAAAACGTTTAATT
GTCGGTGGACTTGAAAAAGTATATGAAATTGGTAGAGTATTCCGTAATGAAGGTGTATCAACTAGACATAACCCTGAATT
CACAATGATTGAATTATATGAAGCATATGCAGATTATCATGACATTATGGATTTAACAGAATCTATGGTGAGACATATTG
CCAATGAAGTATTAGGTTCTGCAAAAGTACAATACAATGGGGAAACGATTGATTTAGAATCTGCTTGGACTCGTTTGCAT
ATTGTTGATGCTGTAAAAGAAGCTACTGGTGTGGATTTTTATGAAGTTAAAAGTGATGAAGAAGCTAAAGCTTTAGCTAA
AGAACATGGTATTGAAATTAAAGATACAATGAAATATGGTCATATTTTAAATGAATTCTTTGAGCAAAAAGTTGAAGAAA
CACTTATTCAGCCAACGTTTATCTATGGTCATCCGACTGAAATTTCACCTTTAGCGAAGAAAAATCCTGAAGATCCTAGA
TTTACTGATCGTTTCGAATTGTTCATTGTAGGTAGAGAGCATGCAAATGCATTTACTGAATTAAATGATCCTATTGATCA
AAAAGGTCGTTTTGAAGCGCAACTTGTTGAAAAGGCGCAAGGTAATGATGAAGCGCATGAAATGGATGAAGATTACATTG
AAGCGTTAGAATATGGTATGCCTCCGACAGGTGGTCTTGGTATCGGTATTGACAGATTGGTTATGTTATTAACTGATTCT
CCATCAATCAGAGACGTGTTATTATTCCCTTATATGAGACAAAAATAA

Protein sequence :
MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAH
VQDLAGQIQIYVRKDQVGDDEFDLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYR
QRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLI
VGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLH
IVDAVKEATGVDFYEVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLAKKNPEDPR
FTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDS
PSIRDVLLFPYMRQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-120 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001441104.1 lysyl-tRNA synthetase VFG1668 Protein 3e-120 50