Gene Information

Name : alr (ESA_00100)
Accession : YP_001436241.1
Strain : Cronobacter sakazakii ATCC BAA-894
Genome accession: NC_009778
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : -
Position : 81985 - 83064 bp
Length : 1080 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCAAGCGGCAACTGTGGTAGTAAACCGCCGCGCTCTGCGTCACAACCTGCAACGCCTGCGTGAACTGGCGCCTGCCAG
CAAGCTGGTTGCGGTGGTGAAGGCAAACGCCTATGGACACGGTCTTCTTGAGACCGCCCGCACTCTTCCTGATGCCGATG
CGTTCGGCGTGGCGCGCCTCGAAGAGGCGCTGCGCCTGCGCGAAGGCGGCATTACCCAACCCATTCTTTTGCTCGAAGGT
TTTTTCAACGCAGCCGATCTGCCCGCGATTGCCGCGCAGCGATTCCACACCGCGGTACACAGCGAAGAGCAACTGGCGGC
ACTGGAGCAGGCGACGCTCTCAGAGCCAGTCACCGTCTGGATGAAGCTCGACACCGGTATGCATCGCTTAGGCGTGCGCC
CGGAGGCGGCGCAGGCGTTTTACGACAGGCTCGCGGCCTGTAAAAACGTACGTCAGCCGGTGAACGTGGTGAGCCATTTC
GCACGTGCCGACGAGCCAGACTGCGGTGCCACCGAACGCCAGCTTGATATCTTTAACAGTTTCACACACGACAAACCGGG
TAAGCGCTCGATTGCCGCCTCCGGCGGGATCCTGTTCTGGCCGCAGTCGCATTTCGACTGGGTGCGCCCCGGCATTATTC
TCTACGGCTTGTCGCCGCTCGATACCCACCCCTGGGGCGCGGAGCTTGGCTTTCAGCCTGCGATGTCACTGACGTCAAGC
CTTATCGCTGTGCGTGACCACAAAGCGGGCGAACCCGTCGGTTATGGCGGCACCTGGGTGAGCGAGCGCGATACGCGGCT
TGGCGTGGTGGCGATGGGCTATGGCGACGGGTATCCGCGCTGCGCGCCGACGGGTACGCCGGTGCTGGTTAATGGCCGTG
AAGTGCCGATTGTCGGGCGCGTGGCGATGGATATGATCTGCGTCGATTTAGGCCCTGACGCGGCGGAAAAAGCGGGTGAT
ACGGTAATCATGTGGGGCGAGGCGCTGCCGGTCGAGCGTATCGCCGAAGCGACGGGAGTGAGTGCTTACGAACTTGTAAC
GCGGCTGACCTCCAGGGTGGCAATGCGTTACCTCGACTGA

Protein sequence :
MQAATVVVNRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLREGGITQPILLLEG
FFNAADLPAIAAQRFHTAVHSEEQLAALEQATLSEPVTVWMKLDTGMHRLGVRPEAAQAFYDRLAACKNVRQPVNVVSHF
ARADEPDCGATERQLDIFNSFTHDKPGKRSIAASGGILFWPQSHFDWVRPGIILYGLSPLDTHPWGAELGFQPAMSLTSS
LIAVRDHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRCAPTGTPVLVNGREVPIVGRVAMDMICVDLGPDAAEKAGD
TVIMWGEALPVERIAEATGVSAYELVTRLTSRVAMRYLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-59 44