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Name : guaA (ESA_00755) Accession : YP_001436868.1 Strain : Cronobacter sakazakii ATCC BAA-894 Genome accession: NC_009778 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 726064 - 727641 bp Length : 1578 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACGGACAACATTCATAAGCATCGTATCCTTATCCTCGACTTCGGTTCTCAGTACACCCAACTGGTGGCGCGCCGCGT GCGTGAGCTGGGCGTTTACTGTGAACTGTGGGCCTGGGACGTGACGGAAGAGCAAATCCGCGGCTTTAATCCTAACGGGA TTATCCTTTCCGGCGGCCCGGAGAGCACCACCGAAGAAAACAGCCCGCGCGCGCCGGAATATGTCTTTAACGCCGGTGTG CCGGTGCTTGGCGTTTGCTACGGTATGCAGACCATGGCGATGCAGCTGGGCGGCCATGTGGAAGGTTCTAACGAGCGTGA ATTCGGTTATGCGCAGGTAGAAGTTAAAACCGACAGCGCGCTGGTGCGTGGTATTGAAGATGCGCTGAGCGCCGACGGCA ACCCGCTGCTGGATGTCTGGATGAGCCACGGCGATAAAGTGACCGCCATTCCGTCTGATTTCGTGACCGTCGCCAGCACC GAAACCTGTCCGTTCGCAATCATGGCGAACGAAGAGAAGCGTTTCTACGGCGTGCAGTTCCACCCGGAAGTGACTCACAC CCGTCAGGGCCTGCGTATGCTGGAGCGCTTCGTGCGCGACATCTGTGAGTGCGAAGCGCTGTGGACGCCGGCGAAAATCA TCGACGACGCGGTTGAGCGCATTCGTCAGCAGGTGGGTAACGATCGCGTGATCCTGGGCCTCTCCGGCGGCGTGGACTCC TCCGTCACCGCCATGCTGCTGCACCGCGCGATTGGCGACCGTCTGACCTGTGTATTCGTTGATAACGGCCTGCTGCGCCT GAACGAAGCCGAGCAGGTGATGGATATGTTCGGTGACCATTTCGGGCTTAACATCGTTCACGTTCCGGCGGAAGCGCGCT TCCTCGACGCGCTGGCGGGCATCGACGAGCCGGAAGCCAAACGTAAAACCATCGGCCGTGTATTTGTGGAAGTGTTCGAC GAAGAAGCGCTGAAGCTGGAAGATGTGAAATGGCTGGCGCAGGGCACTATCTACCCGGATGTGATTGAATCTGCGGCGTC TGCCACCGGCAAAGCGCACGTGATCAAATCTCACCACAACGTGGGCGGCCTGCCGAAAGAGATGAAAATGGGCCTCGTCG AGCCGCTCAAAGAGCTGTTTAAAGACGAAGTGCGCAAAATTGGTCTGGAGCTGGGCCTGCCGTATGACATGCTCTATCGC CACCCGTTCCCGGGGCCGGGTCTCGGTGTGCGCGTGCTGGGCGAAGTGAAAAAAGAGTACTGCGACCTGCTGCGCCGCGC CGACGCTATCTTCATCGAAGAGCTGCGCCGTGCGGATCTCTACGACAAAGTGAGCCAGGCATTCGCGGTGTTCCTGCCGG TGCGCTCTGTCGGCGTGATGGGCGATGGCCGTAAGTATGACTGGGTCGTCTCACTGCGTGCGGTCGAAACCATCGACTTT ATGACCGCTCACTGGGCGCATCTGCCATACGATTTCCTGGGCCGCGTTTCCAACCGCATTATCAATGAAATCAACGGCAT TTCCCGTGTGGTTTATGATATCAGCGGTAAACCGCCCGCGACGATTGAGTGGGAATGA Protein sequence : MTDNIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEEQIRGFNPNGIILSGGPESTTEENSPRAPEYVFNAGV PVLGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVKTDSALVRGIEDALSADGNPLLDVWMSHGDKVTAIPSDFVTVAST ETCPFAIMANEEKRFYGVQFHPEVTHTRQGLRMLERFVRDICECEALWTPAKIIDDAVERIRQQVGNDRVILGLSGGVDS SVTAMLLHRAIGDRLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEARFLDALAGIDEPEAKRKTIGRVFVEVFD EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYR HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRRADLYDKVSQAFAVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF MTAHWAHLPYDFLGRVSNRIINEINGISRVVYDISGKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-129 | 52 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 6e-130 | 52 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 4e-130 | 52 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 1e-111 | 48 |
