Gene Information

Name : leuS (Rcas_0077)
Accession : YP_001430232.1
Strain : Roseiflexus castenholzii DSM 13941
Genome accession: NC_009767
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 96878 - 99592 bp
Length : 2715 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGAGCGACACAGGGACAAAACGGCGTATCGAACGGTTCGATCCGGCGATCGAGCCAAAATGGCGTGAGTTCTGGGAGCG
CGAGGGCATCTTCAAAGCGGGGCGCCGCGCAGGTGCGCCGCGTCGCTATATCCTCGAAATGTTCCCCTATCCCAGTGGCG
ACCTCCACATCGGTCATCTGAAGAACTACGTCATCGGCGATGCGCTGACCCGCTACTATGTCATTCGCGGCTACGATGTG
CTGCATCCCTTTGGGTGGGACGCCTTCGGTCTGCCGGCGGAGAATGCCGCGATCAAGTATGGTCGCCATCCGCGCGAATG
GACTTACGGCAACATCGCCGAGTCGAAGAAGTCGCTCGAGATCGCCGGCATTATGTACGATTGGTCGCGCGAAGTGACGA
CCTGTGATCCTGATTACTACCGCTGGAACCAGTGGCTGTTCCTGTTGCTCTATCGCAAGGGGCTGGCATACCGCGCAAAA
GCGACGGTCAACTGGGACCCGGTGGATCAAACGGTGCTGGCGAACGAACAGGTCGATGCCGAAGGGCGCAGTTGGCGCAG
CGGCGCGAAAGTCGAAAAGCGCGAATTGGAACAGTGGTTCTTCAGGATCACAGCCTATGCCGAGCGCCTGCTGAACGACC
TGGATAAACTGGACAAGTGGCCCGAAAACGTCAAGACCATGCAGCGCAACTGGATCGGCAGGAGTGAAGGCGCCGAAGTC
ACCTTCCTGGCGCTGCCGCCGGGCGCCGACCTGCATGCGCCGCCGCCTCCCGACGCCGAACCGCTGGTGGTGTTCACCAC
CCGCCCTGATACGCTCTGGGGCGCGACGTTCATGGTGCTGGCGCCGGAGCATCCGCTGGTGTCGAAATTGACCGCGCCTG
AACGCCGCGCCGAAGTCGAGGCGTACATCGCCAGAGCGCGTATGGAGAGCGAAATCGAACGCACCAGCGCCACGCGCGAA
AAAACCGGCGTCTTCCTGGGGTCCTACGCGATCAATCCGGTCAATGATGAGCGCATCCCGATCTGGATTGCCGACTATGT
ATTGATGGGGTATGGCGCCGGCGCGATCATGGCGGTGCCTGCGCACGATGAGCGCGACTTCGCGTTTGCCCGTCAGTTCG
GCTTGCCGGTGCGCGTCGTCGTGCAACCGCCGGGCGAAACGCTGGATGGCGCAACGATGACGGAAGCCTGGCCCGGCGAT
GGCGTGATGGTCAATTCGGGACCGATCAACGGTCTTCCGGTCGGCAAAGGGGAAGGGCAGAGCGTCAAGGCGACTATCGC
CTGGCTGGAAGCGAATGGCAAAGGGAAGGGAACCGTCACCTATCGGTTGCGCGACTGGCTGATCAGCCGTCAGCGCTATT
GGGGCACTCCGATCCCGATGCTCCACCTGCCGGATGGGACGATCAAACCGGTGCCGGAGGATCAGTTGCCCGTCGTGCTG
CCCGAAGTGCAGGATTATTTGCCGAAAGGCAAAAGCCCGCTGGCAGCCGCCGAGTCGTGGGTCAATACCATCGACCCCGA
GACCGGACAACCGGCGCGGCGCGATACCGACACAATGGACACGTTTGTGGATTCTTCGTGGTACTTCCTGCGTTTCTGCG
ACGCCAGGAACGACCGCGAAATCTTCTCGCGCGAGGCGGCGCACCGGTGGATGCCGGTCGATCAGTACATCGGCGGCGTC
GAGCACGCCATTCTGCACCTGCTCTATGCGCGCTTCATCACCAAGGTGCTGTACGACGAAGGGTTGGTGCCCGACGATGA
GCCGTTCAGGGCATTGTTCACCCAAGGCATGGTGCAGCGCCGCGTTCGCACACCACTTGAGGTTGTTGCGCCGGGTATGG
TGCGCTTCCCTGAAGAATTGCGGCGCAAACTGGAATTGCCTGCCGATGCACAGAGCCTTGATCAGGCGCGCGCGTTGCTG
AAAGAACGCGGCTATACGCTGGAAGAGGAGAGCAATGGCGGGTTCACCGCCGTATCCGGTCCGGTCACCATGTCGAAGAG
CGCCGGAAATGGCATTCCGGTCGGTCCATTCGTGCGGCAGTACGGCTCCGACGTGGCGCGGATCGTGGTGCTGTTCGCCG
CGCCGCCGGAAAACAGCATGGAATGGACCGACGAAGGGGTTGCCGGAGCGCAACGCTTCCTGAACCGGATCGTGGCGCTG
TTCAGCCCGGATCGGGAGGAGATCGTCGCTGCACTGAACTCCGGCAACGGCGCCGCTCCCGAAGGTGAGGAACGCGCGTT
GTACCGCAAACTGCACGAGACCATCCGCAAGGTGACGCTTGATACCGAACAGTTTCGCTTCAATACCGCAATTGCGGCAT
TGATGGAGTTGCTGAACGAGGCGAGCCGCTACCGCTCCGAGGCGGGTCGGGTGACGCCGGTCTTTGCGCAGACGGCGGCA
ACCTTTGCGCGGTTGCTCTCGCCGTTTGCGCCGCACTTGGCGGAAGAACTGCACTCCTGGTGCGGCGGAACCGGCAGCGT
CTACGATACCGGTTGGCCCGAATGGGACGAAGCAGCGCTGGCGCTCGATGAAGTCGAGATTGTGTTGCAGGTGAACGGCA
AACTGCGTGGCAGGATCATGGCGCCTGCCAATGCTGATGAGCAACAGTTGCGCGAATGGGCGTTGACCAATCCGCGCGTG
CTGAGTTTCGTCGGCGATAAGACCGTGCGCAAGGTTGTGGTTGTGCCTGGGAAACTAGTGAACGTGGTGGTGTAG

Protein sequence :
MSDTGTKRRIERFDPAIEPKWREFWEREGIFKAGRRAGAPRRYILEMFPYPSGDLHIGHLKNYVIGDALTRYYVIRGYDV
LHPFGWDAFGLPAENAAIKYGRHPREWTYGNIAESKKSLEIAGIMYDWSREVTTCDPDYYRWNQWLFLLLYRKGLAYRAK
ATVNWDPVDQTVLANEQVDAEGRSWRSGAKVEKRELEQWFFRITAYAERLLNDLDKLDKWPENVKTMQRNWIGRSEGAEV
TFLALPPGADLHAPPPPDAEPLVVFTTRPDTLWGATFMVLAPEHPLVSKLTAPERRAEVEAYIARARMESEIERTSATRE
KTGVFLGSYAINPVNDERIPIWIADYVLMGYGAGAIMAVPAHDERDFAFARQFGLPVRVVVQPPGETLDGATMTEAWPGD
GVMVNSGPINGLPVGKGEGQSVKATIAWLEANGKGKGTVTYRLRDWLISRQRYWGTPIPMLHLPDGTIKPVPEDQLPVVL
PEVQDYLPKGKSPLAAAESWVNTIDPETGQPARRDTDTMDTFVDSSWYFLRFCDARNDREIFSREAAHRWMPVDQYIGGV
EHAILHLLYARFITKVLYDEGLVPDDEPFRALFTQGMVQRRVRTPLEVVAPGMVRFPEELRRKLELPADAQSLDQARALL
KERGYTLEEESNGGFTAVSGPVTMSKSAGNGIPVGPFVRQYGSDVARIVVLFAAPPENSMEWTDEGVAGAQRFLNRIVAL
FSPDREEIVAALNSGNGAAPEGEERALYRKLHETIRKVTLDTEQFRFNTAIAALMELLNEASRYRSEAGRVTPVFAQTAA
TFARLLSPFAPHLAEELHSWCGGTGSVYDTGWPEWDEAALALDEVEIVLQVNGKLRGRIMAPANADEQQLREWALTNPRV
LSFVGDKTVRKVVVVPGKLVNVVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-161 44