Gene Information

Name : smpB (Rcas_4350)
Accession : YP_001434392.1
Strain : Roseiflexus castenholzii DSM 13941
Genome accession: NC_009767
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 5602175 - 5602651 bp
Length : 477 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCGCGGGGGAATGGCATCGAGCGCGTGGTCGCCGATAATCGTAAGGCGCGCCACGATTATTTCATCGAAGAAACCTA
CGAAGCCGGAGTTGTGCTGACCGGCAGTGAGATCAAGTCTATTCGCGCCGGTCAGGTGAATCTGCGCGGCGGATATGTGC
GCATCGTCAACGGCGAAGCATGGTTGTACGACGTACACATCGCACCGTATGAGCAGTCGGGGAAGTATTTTAATCACGAG
CCGACCCGACCGCGCAAATTGCTGTTGCATCGGCGCGAGATTTCCCGCATTGCCGGGCAGGTCGAGCGACAGGGATATAC
GCTGGTGCCGCTGCGTCTGTATTTACGCGGATCGCGCGCAAAAGTCGAGATCGGGCTGGCGCGCGGGAAGAAGTTGTACG
ACAAACGCGAAGACATCGCGCGCCGTGAGGCACGCCGCACTATTGATCGCGCACTCAAGGAACGAGCGCGCCACTAA

Protein sequence :
MARGNGIERVVADNRKARHDYFIEETYEAGVVLTGSEIKSIRAGQVNLRGGYVRIVNGEAWLYDVHIAPYEQSGKYFNHE
PTRPRKLLLHRREISRIAGQVERQGYTLVPLRLYLRGSRAKVEIGLARGKKLYDKREDIARREARRTIDRALKERARH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 5e-36 54
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-33 53
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-27 48