Gene Information

Name : Rcas_3473 (Rcas_3473)
Accession : YP_001433541.1
Strain : Roseiflexus castenholzii DSM 13941
Genome accession: NC_009767
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4533113 - 4534231 bp
Length : 1119 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rrs:RoseRS_1055 cystathionine gamma-synthase

DNA sequence :
ATGCATCCCGAAACTGCATCCATTCACGCCGGTCAGGAAATCGACCCAACGACGGGCGCGGTCATTCCGCCGATCTACCT
GACGACAACCTTCGAGCGCGCGTCGGACGGGAGTTTTCCGCGCGGGTACATCTACACCCGCAATGGCAACCCTAACCGCG
CAATGCTCGAAACTTGCCTCGCGGCGCTTGAGGGCGGCGCAACATGTGTGGCGTTCAGTTCCGGTCTCGCGGCAGCCATG
AGCGTCTTTCAGGCGCTGCGTCCCGGTGATCACGTGATCGCTCCCGACGACGCCTACCACGGAATCACGCGGCTGCTGCG
CGAGATTATGGCGCCATGGGGACTGGAATACAGCCGCGTCGATATGCGCGACCCGCAGAACGTCGCAGCGGCGTTGCGCC
CGAATACGCGCCTGGTGTGGATTGAGACTCCGTCGAATCCGCTGCTCAAAATCGCTGATATTGCCGCAATTGCGGAGATT
GCCCGTCAGGCTGGCGCACTCTGCGCGGTGGACAACACATGGGCGACGCCGGTGCAGCAGCGCCCGCTGGAATTGGGCGC
CGACATCGTGATGCACGCGACAACGAAGTACATCGGCGGGCATAGCGACGTGCTCGGCGGGGCTGTAGTGTTTGGCGCGA
ACGATGCGTTTGCCGAACGGGTGCGTTTCCTTCAGATCAATGGCGGCGCCGTTCCGTCGCCGTTCGACTGCTGGCTGGCG
CTGCGCGGCATTCAGACGCTCCCCTATCGCGTGCGCGCGCATGCCGCAAATGCGATACAGGTCGCCCGTTTCCTGGCGGA
GCACCCGCGCATCGAGCGCGTTCACTATCCCGGACTGGAAACGCACCCCGGTCACGCGGTTGCTGCGCGGCAGATGCGCG
GCTTTGGCGGCATGCTGTCGATTGAAGTCGAAGGCGGCGAGGCGGAAGCCATGGCAGTCGCTGCGAAGGTCAAGATCATT
ACCCGCGCCACCAGTCTCGGCGGCGTCGAGAGCCTGATCGAACATCGCGCATCGGTAGAGGGACCGGAGAGCACAACGCC
GCCCAACCTGCTGCGCATTTCGGTCGGACTCGAACATCCCGATGACCTGATCGCCGATCTGGCGCAGGCGCTGACATAG

Protein sequence :
MHPETASIHAGQEIDPTTGAVIPPIYLTTTFERASDGSFPRGYIYTRNGNPNRAMLETCLAALEGGATCVAFSSGLAAAM
SVFQALRPGDHVIAPDDAYHGITRLLREIMAPWGLEYSRVDMRDPQNVAAALRPNTRLVWIETPSNPLLKIADIAAIAEI
ARQAGALCAVDNTWATPVQQRPLELGADIVMHATTKYIGGHSDVLGGAVVFGANDAFAERVRFLQINGGAVPSPFDCWLA
LRGIQTLPYRVRAHAANAIQVARFLAEHPRIERVHYPGLETHPGHAVAARQMRGFGGMLSIEVEGGEAEAMAVAAKVKII
TRATSLGGVESLIEHRASVEGPESTTPPNLLRISVGLEHPDDLIADLAQALT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-52 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-54 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rcas_3473 YP_001433541.1 cystathionine gamma-synthase BAC0207 Protein 6e-47 41