Gene Information

Name : hemC (Rcas_2030)
Accession : YP_001432136.1
Strain : Roseiflexus castenholzii DSM 13941
Genome accession: NC_009767
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2602556 - 2603467 bp
Length : 912 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAGAAATTCGCTGACCATTGGCACGCGCGCCAGCAAACTGGCGCTGGTGCAGACGCACATGATCCGCGATGCGTTGCA
GGCGGCGCATCCGGGATTGACCGTTGCTGTTGAACGGATTACGACGCGCGGCGACATTATTCTTGACCGTCCGCTCAATG
CAATCGGTGATAAAGGACTGTTCGTCGTCGAAATCGAGGAGGCGATGCGCGCTGGCAGGGTCGATCTGGCGGTTCATAGC
GCCAAAGATCTGCCCTCGACGCTGCCTCCCGATATGACCCTGGCTGTCTGCCCGCGCCGTGCCGATCCGCGTGATGCGCT
GGTGGCGCAGCCGGGCATGACGCTTGCTTCCCTGCCGCATGGCGCGCGCGTTGGCACGAGCAGCCTGCGGCGCGCCTGTC
AGTTGCGCGCCCTGCGCCCCGATCTGACGCTGCTCGATCTGCGCGGAAATGTCGATACGCGGTTGCGCAAGTTGCGTGAA
GGGCAGTACGATGCCATCGTGCTCGCGGCAGCCGGGTTGAAGCGGCTGGGTCTCGAAGAGGTTATTACGGAACTGCTCGA
ACCAGATGTGCTGATACCGGCGGTTGGGCAGGGAATTATCGGCGTCGAAGCGCGCGCCGGCGATGATGAGGTGCTGCGTC
TGCTGGCGCCGCTCGATGATCCGGCAGCGCGCGCCGCGATCACGGCTGAGCGCGCATTTCTGGCGCGTATCGGTGGTGGT
TGCCGGGTTCCGGTCGGAGCGCTGGCGCTCCTCGAAGGCGATGAATTGCTGCTGTACGGGATGATCGGCGCACTGGACGG
GCGTATGGTGCGCGGTATGCGGAGCGGATCAGCATCGGACCCTGCCGGTCTGGGATCGGCGCTGGCGGAAGAACTGCTCG
ATGCAGGCGGGCAGGCGTTGCTCGCAGGGTAA

Protein sequence : 
MRNSLTIGTRASKLALVQTHMIRDALQAAHPGLTVAVERITTRGDIILDRPLNAIGDKGLFVVEIEEAMRAGRVDLAVHS
AKDLPSTLPPDMTLAVCPRRADPRDALVAQPGMTLASLPHGARVGTSSLRRACQLRALRPDLTLLDLRGNVDTRLRKLRE
GQYDAIVLAAAGLKRLGLEEVITELLEPDVLIPAVGQGIIGVEARAGDDEVLRLLAPLDDPAARAAITAERAFLARIGGG
CRVPVGALALLEGDELLLYGMIGALDGRMVRGMRSGSASDPAGLGSALAEELLDAGGQALLAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-48 53
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-48 53