Gene Information

Name : Rcas_1494 (Rcas_1494)
Accession : YP_001431606.1
Strain : Roseiflexus castenholzii DSM 13941
Genome accession: NC_009767
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1910060 - 1911334 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGACATTCGCCTGATACGTGAGCAACCCGACATGGTCAAAGCGGCGCTTGGGCGGGCAGGCGTCGATCCAGCACA
GGTTGACGCTGTGCTGGCATACGACGAACAACGTCGCGCGCTGCTGCGCGAAGTGGAGAAACTGAAAGCCTTGCGCAATG
CGGTCTCAAAAGAGATCGGCAAGATGAGCGACGCGGGCGAACGCGACACGAAAATCGCCGAAATGCGCGCCGTCGGCGAC
CGCATCGCCGCGCTGGACCGCGAACTCGCTGCGGTGGAAGAGCGGCAGTACGCTGCGCTAATGGAACTGCGCAACCTGCC
GCATCCCGCAGTTCCCGACGGACCGGACGAGACCTACAACGTGGTGATTGCGCAGGAAGGTGAACCGCGCGCCTTCGATT
TTGCGCCAAAGCCACACTGGGAACTCGGCGAAGCGCTCGACATCATCGATTTCGAGCGGGGCGTCAAACTCTCCGGCTCA
CGCTTCTACGTCCTCAAAGGGCTGGGAGCGCGCCTGCAACGCGCCCTGATCCAATGGATGCTCGATCTTCACATCCAACA
GGGATACCACGAGGTCTATACACCGTTCGTGGTAAAAGAGCAATGCATGTGGGGCGCGCGCCAGTTGCCCAAGTTCCGTG
ACAACCTCTACCGCGACGTGGAGGACGACCTGTGGCTGGTGCCGACCGCCGAGGTGCCGGTCACCAATCTCCACCGCGAC
GAGATTCTCGAGGCGGATCAGTTGCCGCTCCGCTATTGCGCCTACACCCCCTGCTTCCGCCGCGAAAAGATGAGCGCCGG
GCGCGATGTGCGCGGCATCAAGCGCGGGCACCAATTCGACAAAGTCGAGATGTACATGTTTGTCCACCCCGACACAAGCT
ACGACGAACTCGAGAAACTACGCGCCGACGCCGAAGCAACCTGTCGTCTGCTGGGATTGACCTTCCGCACCAAAGAACTC
TGCACCGGCGACCTCGGATTTGCCGCCACGCGCACCTACGATATCGAGGTGTGGGCGCCGGGGCAGGGCGAATGGCTCGA
AGTCAGCTCCTGCTCGAATGTCGAAGCCTTTCAGGCGCGGGCAGCGAACATTCGCTACCGTTCAGCGCCGGGGGCGCGTC
CAGAGTATGTCCATACCCTGAACGGCTCAGGGTTGGGGCTGCCGCGCACGCTGATAGCCATTATGGAGAACTACCAGCAG
GCTGATGGCAGCATCATCATTCCTGACGTTCTGCGTCCGTATATGGGGGGGGCTGAGGTTATTCGACGGTCATAA

Protein sequence :
MLDIRLIREQPDMVKAALGRAGVDPAQVDAVLAYDEQRRALLREVEKLKALRNAVSKEIGKMSDAGERDTKIAEMRAVGD
RIAALDRELAAVEERQYAALMELRNLPHPAVPDGPDETYNVVIAQEGEPRAFDFAPKPHWELGEALDIIDFERGVKLSGS
RFYVLKGLGARLQRALIQWMLDLHIQQGYHEVYTPFVVKEQCMWGARQLPKFRDNLYRDVEDDLWLVPTAEVPVTNLHRD
EILEADQLPLRYCAYTPCFRREKMSAGRDVRGIKRGHQFDKVEMYMFVHPDTSYDELEKLRADAEATCRLLGLTFRTKEL
CTGDLGFAATRTYDIEVWAPGQGEWLEVSSCSNVEAFQARAANIRYRSAPGARPEYVHTLNGSGLGLPRTLIAIMENYQQ
ADGSIIIPDVLRPYMGGAEVIRRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-97 51