Gene Information

Name : wbtF (FTA_0631)
Accession : YP_001428063.2
Strain : Francisella tularensis FTNF002-00
Genome accession: NC_009749
Putative virulence/resistance : Virulence
Product : NAD dependent epimerase/dehydratase family protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0451
EC number : -
Position : 585628 - 586611 bp
Length : 984 bp
Strand : +
Note : component of putative O antigen gene cluster

DNA sequence :
TTGGAGATTGTAGTGGCTTACGATAATGTTAAATTTCCTCATGTTTCGTTTTTTTTGGTGACTGGAGGTGCGGGCTTTAT
TGGCTCTAATTTATGTGAAGTTTTACTTAGTAAGGGTTATAGAGTTAGGTGTTTAGATGATCTCTCAAATGGTCACTATC
ATAATGTTGAGCCGTTTTTAACTAATTCTAATTATGAGTTTATAAAAGGTGATATTAGAGATTTAGATACTTGCATGAAA
GCTTGTGAAGGTATTGATTATGTTCTACATCAAGCTGCTTGGGGAAGCGTACCAAGAAGTATTGAGATGCCATTAGTGTA
TGAAGATATAAATGTTAAAGGTACATTAAATATGCTTGAAGCGGCTAGACAAAATAACGTTAAAAAATTTGTCTATGCTT
CTAGTTCATCAGTATATGGTGATGAGCCAAATTTACCTAAAAAAGAAGGTAGAGAAGGAAATGTTTTATCACCCTATGCA
TTTACAAAGAAAGCTAATGAAGAGTGGGCGAGACTATACACAAAGTTATATGGTCTAGATACTTATGGTCTAAGATATTT
TAATGTTTTCGGTAGAAGACAAGATCCTAATGGTGCGTATGCAGCAGTTATACCTAAATTTATCAAACAGTTATTAAATG
ATGAAGCGCCAACTATAAATGGAGATGGTAAACAGTCGAGAGATTTTACATATATAGAGAATGTTATTGAGGCAAATCTT
AAAGCATGTTTAGCAGATAGTAAGTATGCCGGAGAGTCTTTTAATATAGCTTATGGAGGTAGAGAGTATCTTATAGATTT
GTACTATAATCTTTGTGATGCCTTGGGTAAAAAAATAGAGCCAAATTTTGGTCCAGATAGAGCGGGTGATATTAAGCATA
GTAATGCTGATATTTCGAAGGCTAGGAATATGCTCGGATATAATCCGGAATATGATTTTGAATTAGGCATAAAGCATGCT
GTTGAGTGGTATTTAATTAATTAA

Protein sequence :
MEIVVAYDNVKFPHVSFFLVTGGAGFIGSNLCEVLLSKGYRVRCLDDLSNGHYHNVEPFLTNSNYEFIKGDIRDLDTCMK
ACEGIDYVLHQAAWGSVPRSIEMPLVYEDINVKGTLNMLEAARQNNVKKFVYASSSSVYGDEPNLPKKEGREGNVLSPYA
FTKKANEEWARLYTKLYGLDTYGLRYFNVFGRRQDPNGAYAAVIPKFIKQLLNDEAPTINGDGKQSRDFTYIENVIEANL
KACLADSKYAGESFNIAYGGREYLIDLYYNLCDALGKKIEPNFGPDRAGDIKHSNADISKARNMLGYNPEYDFELGIKHA
VEWYLIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviC NP_458739.1 Vi polysaccharide biosynthesis protein, epimerase Virulence SPI-7 Protein 6e-62 51
tviC NP_807944.1 VI polysaccharide biosynthesis epimerase Virulence SPI-7 Protein 6e-62 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wbtF YP_001428063.2 NAD dependent epimerase/dehydratase family protein VFG0430 Protein 2e-62 51