Gene Information

Name : FTA_0502 (FTA_0502)
Accession : YP_001427934.1
Strain : Francisella tularensis FTNF002-00
Genome accession: NC_009749
Putative virulence/resistance : Virulence
Product : Orn/Lys/Arg decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.-
Position : 454575 - 456716 bp
Length : 2142 bp
Strand : +
Note : -

DNA sequence :
ATGAAAACTGTTGTATTTGTCTATAAAGATACCTTAAAGTCATATAAGGAAAAATTTTTACTAAAAATTGAGAAAGATCT
TAAAAATCATCATGAGTATTATACTTTGAAGCTTGATGATTTATCCGAAGTGGTTGAAATTCTTGAGGAGAACTCTAGAA
TATGCTGTATTGTTTTAGATAGAGCTAGTTTCAATATTGAAGCTTTTCATAATATTGCGCACCTTAATACAAAGCTGCCA
ATATTTGTAGCATCTGACTATAGTCAAAGTATTAAGCTTAATCTGCGTGATTTTAATCTAAATATCAACTTCTTGCAGTA
TGATGCTTTAGCTGGTGAGGATTCTGACTTTATTCACAAAACTATCACAAATTATTTTAATTATATATTGCCACCGTTGA
CTTATGAGTTATTTAAGTACTCTAAATCTTTTAATTCGGCTTTTTGTACTCCAGGTCACCAAGGAGGTTATGGTTTTCAG
CGTTCTGCAGTAGGGGCTTTGTTTTATGATTTTTATGGCGAGAATATTTTTAAGACAGATTTATCTATTTCAATGAAAGA
GCTGGGAAGCTTGCTTGATCATTCTGAAGCACATAAGGACGCTGAAGAATATATATCTAAAGTTTTTAAATCAGACAGAT
CACTTATTGTTACAAATGGTACTTCAACAGCTAATAAAATAGTGGGAATGTATAGTGTTGCTGATGGTGATACGATTCTT
GTAGATAGAAATTGCCATAAATCAGTGACACATCTAATGATGATGGTTGATGTTAACCCAATATATCTAAAACCAACCAG
AAATGCTTATGGAATAATTGGTGGGATTCCTAAAAAAGAGTTCAAAAGAGAAACTATCCAAGAAAAGATAGATAATAGTA
ATATTGCTGATAAGTGGCCTGAATATGCGGTAGTTACAAACTCAACTTATGACGGTATCCTTTATAATACTGATACGATA
CATCGAGAGCTTGATGTTAAAAAACTACATTTTGATAGTGCTTGGATACCATATGCAATATTTCATCCAATTTATAAGCA
TAAATCAGCAATGCAAATTGAGCCAAGACCAGAACATATAATTTTTGAAACACAGTCAACACATAAACTTTTAGCGGCCT
TTAGCCAATCATCAATGCTGCATATAAAAGGCGACTATAATGAAGAAGTATTAAATGAAGCGTTTATGCTGCATACTTCA
ACATCACCTTTTTATCCGATAGTTGCTAGCGTGGAAACAGCAGCAGCAATGATGGAGGGCGAGCAAGGCTATAATCTTAT
CGACAAGACTATTAACTTAGCTATAGATTTTAGAAGAGAACTAATCAAACTAAGATCTGAAGCAAATGGTTGGTTTTTTG
ATGTTTGGCAACCTGATAATATCTCTAATAAAGAGGCATGGCTTCTGAGAAATGCTGATAAATGGCATGGATTTAAAAAT
GTTGATGGTGATTTTCTCTCATTAGACCCTATCAAAATAACAATTCTAACTCCTGGGATAAAAGATAATGATGTTCAAGA
TTGGGGAGTACCAGCTGATGTGGTCGCTAAATTCTTAGATGAGCATGATATTGTGGTTGAGAAGTCTGGACCATATTCAT
TACTATTTATATTTAGTTTAGGTACAACAAAAGCTAAATCAGTAAGGCTAATTTCGGTATTGAATAAATTCAAACAAATG
TATGATGAAAATACACTTGTTGAAAAAATGCTACCAACTTTATATGCGGAAGATCCTAAATTTTATGAAGATATGAGAAT
TCAAGAAGTTAGTGAAAGATTACATCAGTATATGAAAGAGGCTAATCTTCCTAATCTCATGTATCATGCTTTTAATGTGC
TACCAGAGCAACAGCTAAATCCTCATAGGGCTTTTCAGAAATTATTAAAAGGTAAGGTTAAAAAGGTTCCTCTAGTAGAA
CTGTATGAGCATACTTCAGCTGTTATGATATTACCTTATCCACCTGGGATACCTGTTATTTTTCCTGGAGAGAAGATAAC
CGAAGAATCTAAAGTAATATTGGATTTCTTATTAATGCTTGAGAAAATAGGTTCGATGTTGCCTGGCTTTGATACAGATA
TTCATGGTCCTGAGAGGGCAAAAGATGGTAAGCTCTATATCAAAGTTATTGATGATAAATAA

Protein sequence :
MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLDRASFNIEAFHNIAHLNTKLP
IFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHKTITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQ
RSAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVADGDTIL
VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWPEYAVVTNSTYDGILYNTDTI
HRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTS
TSPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN
VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQM
YDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVE
LYEHTSAVMILPYPPGIPVIFPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 55
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 5e-168 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FTA_0502 YP_001427934.1 Orn/Lys/Arg decarboxylase VFG1670 Protein 3e-168 50