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Name : pdpA1 (FTA_0134) Accession : YP_001427568.1 Strain : Francisella tularensis FTNF002-00 Genome accession: NC_009749 Putative virulence/resistance : Virulence Product : pathogenicity deteminant protein PdpA Function : - COG functional category : - COG ID : - EC number : - Position : 121574 - 124036 bp Length : 2463 bp Strand : - Note : Several Francisella pathogenicity island (FPI) genes, including iglC, iglD, and pdpA to pdpD, regulated by MglA are necessary for replication in macrophages and for virulence. PMID:15375123, PMID:17000729 DNA sequence : ATGATAGCAGTAAAAGATATAACTGATTTAAATATACAAGACATAATTAGTCAGTTAACTTCTGAAGTTATAAATGGCGA CACAACCTCTTCTTCTGCCAAGTTTGCTTGTGAAATTAATAGCTATATTATTAATTACAAACTATTAAACATTAATCTTA TTAATACTCAACTAAAAAATACAAAGATACTTTATAGAAAAGGCTTGATATCTAAGCTTGATTACGAAAAATATAAAAGA TATTGCGTAATATGTAGATTAAAAAATAACATAGATGAATTTATCTTATATTTTTCGACAAACTATAAAGACTCTCAAAG CTTAAAAATCGCAATTAAAGAATTACAAAACTCATGCTCATCAAGTTTAATTCTTGAGCTCCCTCATGATTACATAAGAA AAATTGATGTCTTACTAACTAGTATAGATAGTGCGATACAAAGATCAAGTGATCTCAACAAAACAATTATAAAACAGTTA AATAAGCTTAAAAGCAGCCTTTCACGATATATTGGGTATAATAATGTACTGCAAAAACAAGAAATTACTATAAATATAAA GCCTATTAATAAAAATTTTGAACTTGAGGATATAAGTTTTGTATCAACTAGAAATAAGCAATATTTTAAGCATAACTCTC TTACACTTAAAAATCCTCATATTGAAAAATTAGAAGTATGTGAAAATATCTACGGCATAAATGGCTGGTTAACTTTTGAT TTAGCATATATCAATAATCACAAAGACTTTAACTTCCTATTAAGCCCAAATCAACCCATATTATTTGATATTCAAATTAA TGATAGCTTCAATTTTTACAAAAAAGAATCTAAAAAAGATCATCATAAGAGAACAACCCGTTTTATGGCCATTGGCTTTA ATTCAAACAGTATAGATATTCATGAGAACTTTGAATACAGCATATATTCTTATACCAAAAATGTTTCTTCAGGAGTAAAA AAAATTAAAATACAATTCCATGACCCACTAAAAGCACTTTGGACTAAGCACAAACCATCTTATATAGCTTTAAATAAAAG CTTAGATGATATCTTTAAAGAGAATTTTTTCTTTGATAATTTAGTTTCTTTAGATACCAACAAAAGTAATAACCTAAAAA TACGTATACCACAAGCATTTATTTCTACAGTTAATCGAAATTTTTATGATTTTTTTATTCAACAACTTGAGCAAAATAAA TGCTATTTAAAATATTTCTGTGATAAGAAGAGTGGCAAAGTAAGCTATCATGTTGTAGATCAAGTAGATAATGACTTACA AAGGAATATCGTAAATTCAGATGAAGATTTAAAAGACAAACTATCTCCTTATGATATAAGCTGCTTCAAAAAACAAATTC TAATCTCAAATAAATCAAACTTTTATGTTAAAGAAAAAAATATATGTCCTGATGTGACTTTAACCACTCAAAAAAAGGAA GATCGAAAGATTTCAGATACCCTAATAAAGCCATTCTCATCCATACTCAAGGATAACTTACAATCTGTAGAGTATATACA AAGCAATAATGATGATATACAAGAAATTATTACTACAGGATTTGAGATATTACTGACATCAAGAAATACTCTGCCCTTCT TAGATACTGAAATTACTCTTTCTAAACTAGACAATGATCAAAACTATCTTTTAGGCGCAACAGATATAAAAAGCTTATAT ATAAGTCAAAGAAAGCTATTATTTAAAAGAAGTAAATACTGCTCTAAACAACTATATGAAAACTTACATAATTTTCACTA TAAAAGTGATTCTGAATCAGACGTATATGAAAAAATTGCTTTTACTAAATACCCTAGTCTGACACATGACAACTTAATAA CTTATAAAATTAAGAATTATAGTAATCTAACTCCTGAATATCCTAAGTACAAAAGTTTTAGTAACTTTTATATTAATGGT AGAGTAACGATTGGAGAAAATGTTAATAATGACTCCAAAAAAGCTTATAAATTCTTTAAAAATTATAAGCCAGAAGAAAG CTCAATCGCAGAATTTCAAGAAAATGGTGAAAAAGGTACTTCAGCTATACTAAATAGTAAGGCTGATATCTTATACGCAA TAGAAATTGCCAAGGAAATGTTATCTGATAAATCATCAGATAAGCCAATCATATACTTACCTCTAAAAGTAAACATAAAT TCTGCTAATAATCAATTTATACCATTGAGAAATGACGATATTATCTTAATTGAAATGCAGTCTTTTACTAAAGGTGAAAT TATTGAGTTAATTTCAAACTCTGCCATATCAACAAAGAAAGCTCAGCAGCAACTACTACAACGACAACTTCTTGGATCTA AAGAAAACTGTGAAATGGCATATACCCAAACAAGTGATAGCGAGACATTCTCACTAACTCAAGTAAATGAAGATTGTGAG AATTCTTTTTTGATAAATGATAAAAAAGGTATTTTTCTAAGATATAAATCAAAAGGAAATTAA Protein sequence : MIAVKDITDLNIQDIISQLTSEVINGDTTSSSAKFACEINSYIINYKLLNINLINTQLKNTKILYRKGLISKLDYEKYKR YCVICRLKNNIDEFILYFSTNYKDSQSLKIAIKELQNSCSSSLILELPHDYIRKIDVLLTSIDSAIQRSSDLNKTIIKQL NKLKSSLSRYIGYNNVLQKQEITINIKPINKNFELEDISFVSTRNKQYFKHNSLTLKNPHIEKLEVCENIYGINGWLTFD LAYINNHKDFNFLLSPNQPILFDIQINDSFNFYKKESKKDHHKRTTRFMAIGFNSNSIDIHENFEYSIYSYTKNVSSGVK KIKIQFHDPLKALWTKHKPSYIALNKSLDDIFKENFFFDNLVSLDTNKSNNLKIRIPQAFISTVNRNFYDFFIQQLEQNK CYLKYFCDKKSGKVSYHVVDQVDNDLQRNIVNSDEDLKDKLSPYDISCFKKQILISNKSNFYVKEKNICPDVTLTTQKKE DRKISDTLIKPFSSILKDNLQSVEYIQSNNDDIQEIITTGFEILLTSRNTLPFLDTEITLSKLDNDQNYLLGATDIKSLY ISQRKLLFKRSKYCSKQLYENLHNFHYKSDSESDVYEKIAFTKYPSLTHDNLITYKIKNYSNLTPEYPKYKSFSNFYING RVTIGENVNNDSKKAYKFFKNYKPEESSIAEFQENGEKGTSAILNSKADILYAIEIAKEMLSDKSSDKPIIYLPLKVNIN SANNQFIPLRNDDIILIEMQSFTKGEIIELISNSAISTKKAQQQLLQRQLLGSKENCEMAYTQTSDSETFSLTQVNEDCE NSFLINDKKGIFLRYKSKGN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pdpA1 | YP_001891763.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpA2 | YP_001892258.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpA1 | YP_001121177.1 | pathogenicity deteminant protein pdpA1 | Virulence | FPI | Protein | 0.0 | 99 |
| pdpA2 | YP_001121580.1 | pathogenicity determinant protein, pdpA | Virulence | FPI | Protein | 0.0 | 99 |
| pdpA1 | YP_170296.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpA2 | YP_170604.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpA | AAP58968.1 | PdpA | Virulence | FPI | Protein | 0.0 | 98 |
