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Name : pdpB1 (FTA_0133) Accession : YP_001427567.1 Strain : Francisella tularensis FTNF002-00 Genome accession: NC_009749 Putative virulence/resistance : Virulence Product : pathogenicity deteminant protein PdpB Function : - COG functional category : S : Function unknown COG ID : COG3523 EC number : - Position : 118288 - 121569 bp Length : 3282 bp Strand : - Note : Several Francisella pathogenicity island (FPI) genes, including iglC, iglD, and pdpA to pdpD, regulated by MglA are necessary for replication in macrophages and for virulence. PMID:15375123, PMID:17000729 DNA sequence : ATGAATTTTATTAAAAATCATCAAATATTAATAATTTCACTAACTATAGCAATAATTGTTTTATCAGTACTTGGTATTTT TATGATTAAAAAATGGCTTAAAACATCAAGAAATCCTAACAAAAAATCTGCCTCAAAGACCATAAAAAATGCGAAATCAT TGATCAAAAAGAATAAAGTAAAAAACAACTTAAGTGAATTGTATATTTTCTATGGGGACTATCTGGCAGCTAAAGATTAT ATAACAAAGATAAAACCTCAAGCTCAAATCATTGATAATAATGAACTCCCTTTAATAGCTATTGATAAAAACAATACATC TCTCGTATTTGCAAATAATGAATTTTCGTACCTATATAAGTTAAAAAAGAAACTAAATCTACAATTTTATAAGCTTAACT TTTGCTTCGATATATCCGATGATTACTATCATGAAAATATCAAAATTAGTGAAATCTATAAAGAACTATTAAAATTAAGA TTAAAAAACTTCATAATATCTTTTTACACCTTATCTGAGCATACTAGAAGCTATAATAATGCAATTGATAAAAAATCAAT ATTTAAATTAACTTCTGATGCGGATACAAATCATAAAGCTGAAGAGGAAATATTATCAAAAATTCTTAGCTCTAAAGATG ATGTTAATAATAAATACAATAATGTTAAGATATTAAATCAAATAAGAAAGTTGCTAAAAAACATCCACCCTCAATTAAAA TCTATAAATAAAGAAACATTCTTTAATTTTGGGCTAAACACACCAGATAATATCATAGCAAAGAAAGATACAATATTTTT TAGCAGCTTTCCAAAAAGTATTATCATAAACTTAATATCTTTGTTATTTAGTTTTATATTTATCGTTAATATTTTTCAAG AAATTAATATTAAAAAAAAATTCTCTATACAAGAACTTAATCAACTACATGAAAGCGACTCTAATAAAATAATAGAAGAA ACTAGAAAAAAAATTGATGAGGCTATACTTCTAGATATCCTATATCCGAAATCGATAAAATATCATTTCATATACAAACA ATATGCTGATACTCTCCTAAAGAATGTAATCTTACCAAAATATAATGATACATATGACTTATCAATGATTACATCATTTT TAATATTTTTTGAGTATTTGGATAACAAAATTATTAACCAACATACGAATAGAATACTTAAAATAATAAGCAGTATCACC AACCTATCTGAAAAGCAGCTAGATATCGTGGTCAAGTATACGACCCCAAGTATAAGAACTGAAATGATTAAGTCAGCCAT CAACAGAGCAAATAAACTTTATACAAATCGTTTAATAGTTGTAGGTAAAGACTCCAAAAGTTACTTAAGTACTAAAGGAT TTAATGCTGAATACTTAGGGATTTCAAATACTAAAAGAGCGAAGGTCATAAATAATATTTATATACAATACCTATATAAA TGTGCTACAGATAATGCAATTTTAGATTTAAACGATAACTACATAATACCAATAGAAGTAAATAATATCTTCAAGATGTA TCAAGAGCAATTTGACACATCCTCTAAAAAGCTATGTAACTCATCATATATTAACTCTATTACAAAGAGCGTTTCTTTGA TACTTAATCAAGAGGAAAATAAAAGAAAATTTGAAAGCTTCAGTGATATGCTAGACCATATCTATTATTTAGTAAAATCA TTAGAAAAAAATGCTAAAGATGTCGCAGATGATGGTAAAAAACAAACTAGCTCGATAACAGTATCGCTTATAAATTACGT TATAAATAGTGTTGTCAACCCTACTTATAATAAAAATGAGCTCCCACTAATAAGTCCAGTAAGTAAAAACCTATATATGG AGTTTGCTCCTAATTTCTATAGTAAAAGAATACTTATCTCTCCAATATACTCAAAAGAATATATTAAAGATAATATAGAT CCTACAAATAAAAAGTTTAATAGACTCGTCAATAATCTAAAGAATAACTTCAATATAGAACCCGACTTTATGATTGCTAT CTATAAAAGCTCTATAAATAACTACATTGAGAAATATATAGGATCCTATAATAAGATGATTGATAGCCTTAATAATGACT CTGAATTTAACAAAAATATATCTAACAAGGGTGCTCTTAAATTATATTTGCTAGCAATGTCATCAAAGGATTCTTCCTTT AATAGCCTAATAGAGTTTTATAGCACTAATACAGACCTAATAACTAATGAATCCGAAACCAATTCATCTAAAAAGATAAA TAAGCTTCAACATTTTTATGGAGAAATAACTAAATTAAACAAACAAAATAATACTAATGATCAAAATGATAAGTCATTGT GGGCGCCTATAGATAACTACTTTAAAGAAAACGATAAATATCTTGAGTCTAAGAGTTATGCCGACTATAAAAACATATTT AAACAGTTAAATAATCTAATAATAGAACAAGGCTATTCAAGTACATATAAAAATATCAAACAAGGATATGAACCACTACA AAAAGTTTACTCTGAACTTTCTAAGATAAATAATCATCAAGGTAATAATAACTTATATAAACTGTTGAAGAAACATCTAG ATATTGCCATTAATACTATAAAAACTATCGCCATACAAGATGCTATAACTAAACTTGATAATACTGTCAATATTGAGTAC GAATACATAAATAATCAATTCCCTTTTAATAAGGATAGTAACTCGGCTGCAACAAATGAAGCTATAACCAAAGACTTTGA TAACAATGGTTATATATACTCTGGATTTATAGAGCAACTATCTCCACTACTTTTTTATAATAAAACTGATGATAGATGGG AAAGTAAAGATTTTTCAAAACCTGAGGAAATAGACTATCTAAATAAATTCAATAAGGTATATCTTTTAAATAAGCTACTA TGGGATGATAAAATAAATCCAAAAGCTATAAAATTTGATATAACTCCTATACCAAACAAAGATAATGATTATACATTTTT TAGCATAATCCTCGATAAGCAAAACTATGTAAACTCATTAAACATAAAATATTCAGATAGTATTGAAGTTTTGTACAACT GGAATTCACTTGAGTCAACAACTATTACCATAAAATTTGAGGATGGTAGTAATGAGCAAATAAGCTATCAAGGAAAATGG TCTATATTAAAAGCAATTAAAGACGCAAATTGTGATCAAAACAATATTTGTACCTGGATAATCAAGCACAAAGGTAAAAA ATATCCTTTAAGCTTCAAAATAGAATCAAAATTCTTACAAGTATTAGGATGGCAAAAACAAGGAGAAGTCAATGTACAAT AA Protein sequence : MNFIKNHQILIISLTIAIIVLSVLGIFMIKKWLKTSRNPNKKSASKTIKNAKSLIKKNKVKNNLSELYIFYGDYLAAKDY ITKIKPQAQIIDNNELPLIAIDKNNTSLVFANNEFSYLYKLKKKLNLQFYKLNFCFDISDDYYHENIKISEIYKELLKLR LKNFIISFYTLSEHTRSYNNAIDKKSIFKLTSDADTNHKAEEEILSKILSSKDDVNNKYNNVKILNQIRKLLKNIHPQLK SINKETFFNFGLNTPDNIIAKKDTIFFSSFPKSIIINLISLLFSFIFIVNIFQEINIKKKFSIQELNQLHESDSNKIIEE TRKKIDEAILLDILYPKSIKYHFIYKQYADTLLKNVILPKYNDTYDLSMITSFLIFFEYLDNKIINQHTNRILKIISSIT NLSEKQLDIVVKYTTPSIRTEMIKSAINRANKLYTNRLIVVGKDSKSYLSTKGFNAEYLGISNTKRAKVINNIYIQYLYK CATDNAILDLNDNYIIPIEVNNIFKMYQEQFDTSSKKLCNSSYINSITKSVSLILNQEENKRKFESFSDMLDHIYYLVKS LEKNAKDVADDGKKQTSSITVSLINYVINSVVNPTYNKNELPLISPVSKNLYMEFAPNFYSKRILISPIYSKEYIKDNID PTNKKFNRLVNNLKNNFNIEPDFMIAIYKSSINNYIEKYIGSYNKMIDSLNNDSEFNKNISNKGALKLYLLAMSSKDSSF NSLIEFYSTNTDLITNESETNSSKKINKLQHFYGEITKLNKQNNTNDQNDKSLWAPIDNYFKENDKYLESKSYADYKNIF KQLNNLIIEQGYSSTYKNIKQGYEPLQKVYSELSKINNHQGNNNLYKLLKKHLDIAINTIKTIAIQDAITKLDNTVNIEY EYINNQFPFNKDSNSAATNEAITKDFDNNGYIYSGFIEQLSPLLFYNKTDDRWESKDFSKPEEIDYLNKFNKVYLLNKLL WDDKINPKAIKFDITPIPNKDNDYTFFSIILDKQNYVNSLNIKYSDSIEVLYNWNSLESTTITIKFEDGSNEQISYQGKW SILKAIKDANCDQNNICTWIIKHKGKKYPLSFKIESKFLQVLGWQKQGEVNVQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pdpB1 | YP_001891764.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpB2 | YP_001892259.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpB1 | YP_170297.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpB2 | YP_170605.1 | hypothetical protein | Not tested | FPI | Protein | 0.0 | 99 |
| pdpB1 | YP_001121176.1 | pathogenicity deteminant protein pdpB1 | Virulence | FPI | Protein | 0.0 | 99 |
| pdpB2 | YP_001121579.1 | pathogenicity determinant protein pdpB2 | Virulence | FPI | Protein | 0.0 | 99 |
| pdpB | AAP58967.1 | PdpB | Not tested | FPI | Protein | 0.0 | 97 |
