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Name : iglAII (FTA_1220) Accession : YP_001428652.2 Strain : Francisella tularensis FTNF002-00 Genome accession: NC_009749 Putative virulence/resistance : Virulence Product : intracellular growth locus AII Function : - COG functional category : S : Function unknown COG ID : COG3516 EC number : - Position : 1097858 - 1098448 bp Length : 591 bp Strand : + Note : Several genes in Francisella necessary for replication in macrophages and for virulence including iglA, iglC, and iglD and pathogenicity determinant protein genes pdpD and pdpA, are regulated by MglA. PMID:15375123, PMID:17000729 DNA sequence : TTGCTTATAAGGTGTTGTGAAAAAAAGGACAATAAGATGGCAAAAAATAAAATCCCAAATTCAAGGTTGATGATAAATTA TGAAACTAATGTTGATGGTGTCTTAAAGAAAAAAGAGCTACCTTACAGAGTCCTAGTTGTTGGCGATTTATCAAAAGGAA GATCTGTGGATGCAAAAAAAGAGTTCGCATATAGAGAGGTCAGAAGAGTAAATAATGGTGTTGATAGGGTTTTAGAAGAG ATGAATATATCTTTTGATTTTGAGGCACCAAACTTTGTTTCTAAAGATCCTAGTAATTTAAAAGTTAATTATAGAATTGA AAGTGTCAAAGATTTTAGACCTGATGCTGTTGCTAAAAAAGTTCCTGAAATCAGAGCGCTGCTTGAAATGAAAGAGATAT TAGCATCCTTTGCTAAGGACATTGAAAATAATCGTAATCTCAAGAAAACCATAGATATGATTTTTTCAGATAGTAACGAA TTAGAATCATTAAAGAGTAAGATTCCTGCTTTGACAAATTATACGATTAAAGACTCTTGTGATGCTGCTGGGTCTCAAGA CTTAAGTAATCAACAAGTAGATGGTAAGTAG Protein sequence : MLIRCCEKKDNKMAKNKIPNSRLMINYETNVDGVLKKKELPYRVLVVGDLSKGRSVDAKKEFAYREVRRVNNGVDRVLEE MNISFDFEAPNFVSKDPSNLKVNYRIESVKDFRPDAVAKKVPEIRALLEMKEILASFAKDIENNRNLKKTIDMIFSDSNE LESLKSKIPALTNYTIKDSCDAAGSQDLSNQQVDGK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| iglA1 | YP_170311.1 | intracellular growth locus subunit A | Not tested | FPI | Protein | 2e-83 | 99 |
| iglA2 | YP_170619.1 | intracellular growth locus subunit A | Not tested | FPI | Protein | 2e-83 | 99 |
| iglA1 | YP_001121162.1 | intracellular growth locus, igl A | Virulence | FPI | Protein | 3e-77 | 99 |
| iglA2 | YP_001121565.1 | intracellular growth locus, iglA | Virulence | FPI | Protein | 3e-77 | 99 |
| iglA1 | YP_001891778.1 | intracellular growth locus protein A | Virulence | FPI | Protein | 7e-78 | 99 |
| iglA2 | YP_001892273.1 | intracellular growth locus protein A | Virulence | FPI | Protein | 7e-78 | 99 |
| iglA | AAP58962.1 | IglA | Virulence | FPI | Protein | 5e-77 | 98 |
