Gene Information

Name : tkt (FTA_1208)
Accession : YP_001428640.1
Strain : Francisella tularensis FTNF002-00
Genome accession: NC_009749
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1086563 - 1088554 bp
Length : 1992 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCTTTATCTATTCCACGCGAGTTTTCAAACGCTATAAGATTTTTATCTATTGATGCAACACTTAAAGCTAAATCAGG
ACATCCTGGAATGCCTATGGGGATGGCTGATATTGCCACAGTGTTATGGACAAAGTTTCTTAAGCACAATCCAAATAATC
CACATTGGATAAATAGAGATAGATTTGTTCTTTCAAATGGGCATGGCTCAATGCTTTTATATTCTCTGTTACATCTGACA
GGTTATGATCTATCTATTGAGGATATTAAAAATTTTAGGCAGTTACACTCAAAAACTCCAGGGCACCCTGAGTATGGCTA
TATGCCAGGAGTTGAGACAACAACTGGTCCATTAGGGCAAGGAGTAGCAAATGCTGTGGGTATGGCTTTAGGTGAAAAGC
TATTATCAGATAGGTATAATACACCTGATTTAAAAGTTATAGATCATCACACTTACGTGTTTTTAGGTGATGGATGTTTG
ATGGAGGGTGTTTCTCATGAAGCATGCTCATTAGCAGGGACTCTAGGTTTAAACAAATTAGTAGCATTTTGGGATGATAA
TAATATTTCGATAGATGGCGATACTAAGGGTTGGTTTAGTGATAATACACCTGAGAGATTTAGGGCGTATGGTTGGCATG
TTATAGAAAATGTTGATGGTCATGAGTTTGTTGCGATTGAAAAAGCTATAAATGAAGCCCATTCTCAGCAGCAAAAACCA
ACTTTAATCTGTTGTAAAACTGTAATTGGTTTTGGCTCACCTGAGAAAGCTGGAACTGCCTCTGTGCATGGTTCGCCTTT
AAGTGATCAAGAAAGAGCCTCAGCTGCTAAAGAGCTTAACTGGGATTATCAAGCTTTTGAAATACCTCAAGATGTTTATA
AATACTGGGATGCTAGGGAAAAAGGACAAGCTTTAGAAGCAAATTGGCAAGGGCAATGGAATTTATTTAAAGACAGTCCT
AAGTTTGACGAATTTGAACGAGTTTTAAGTAAAGAGTTGCCAGTTGGATTAGAAAGCGCTATTAATGACTATATAGCTTC
GCAATTGAGTAATCCTGTCAAAGTGGCAACACGTAAAGCTTCACAAATGGCGCTTGAAGTCTTGTGTAAGAATATGCCTG
AGATGTTTGGTGGATCAGCAGATTTGACAGGATCAAATAATACTAATTGGAGTGGTTCAGTTTGGCTAAATAATACTCAA
GAAGGCGCAAATTATCTTTCTTATGGTGTTAGAGAGTTTGGTATGGCTGCAATAATGAATGGTCTAAGCCTTTATGGTGG
TATCAAACCTTATGGTGGTACATTCTTGGTATTTAGCGATTATTCAAGAAACGCGATAAGAATGTCAGCGTTGATGAAAC
AGCCTGTAGTTCATGTTATGTCGCATGACTCAATTGGTTTGGGAGAAGATGGACCAACTCATCAACCTATAGAACATGTT
CCGAGTTTAAGACTTATACCTAACTTAAGTGTTTGGCGACCTGCTGATACAATTGAAACAATGATAGCATGGAAAGAGGC
TGTAAAATCTAAAGATACGCCAAGTGTAATGGTACTTACACGTCAAAACTTAATGCCAGTAGTGCAAACACAGCATCAGG
TAGCAAATATTGCTAGAGGTGGTTATCTAGTTAAAGATAATCCTGATGCTAAATTAACTATTGTTGCTACTGGCTCTGAA
GTTGAGCTTGCTGTCAAAGTTGCTAATGAATTTGAAAAGAAAGGTATAAAATTAAATGTTGCTTCTATACCGTGTGTAGA
AGTTTTTGCTACTCAAGCTCACGAGTATAAAAAAACAGTAATAAAAGATGATATCCCGGCAGTTTTTGTTGAGATGGCGC
AACCTGATATGTGGTATAAATATATGCCAAAAGCTGGAGGGGAAGTAAAAGGAATCTATAGCTTTGGTGAGTCAGCACCG
GTTGAAGATTTATTTAAACATTTTGGATTTACTGTAGAAAATATTAGCAATATTGTTGCTAAATATGTTTAA

Protein sequence :
MSLSIPREFSNAIRFLSIDATLKAKSGHPGMPMGMADIATVLWTKFLKHNPNNPHWINRDRFVLSNGHGSMLLYSLLHLT
GYDLSIEDIKNFRQLHSKTPGHPEYGYMPGVETTTGPLGQGVANAVGMALGEKLLSDRYNTPDLKVIDHHTYVFLGDGCL
MEGVSHEACSLAGTLGLNKLVAFWDDNNISIDGDTKGWFSDNTPERFRAYGWHVIENVDGHEFVAIEKAINEAHSQQQKP
TLICCKTVIGFGSPEKAGTASVHGSPLSDQERASAAKELNWDYQAFEIPQDVYKYWDAREKGQALEANWQGQWNLFKDSP
KFDEFERVLSKELPVGLESAINDYIASQLSNPVKVATRKASQMALEVLCKNMPEMFGGSADLTGSNNTNWSGSVWLNNTQ
EGANYLSYGVREFGMAAIMNGLSLYGGIKPYGGTFLVFSDYSRNAIRMSALMKQPVVHVMSHDSIGLGEDGPTHQPIEHV
PSLRLIPNLSVWRPADTIETMIAWKEAVKSKDTPSVMVLTRQNLMPVVQTQHQVANIARGGYLVKDNPDAKLTIVATGSE
VELAVKVANEFEKKGIKLNVASIPCVEVFATQAHEYKKTVIKDDIPAVFVEMAQPDMWYKYMPKAGGEVKGIYSFGESAP
VEDLFKHFGFTVENISNIVAKYV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 56
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 4e-180 55