Gene Information

Name : iglA1 (FTA_0119)
Accession : YP_001427553.1
Strain : Francisella tularensis FTNF002-00
Genome accession: NC_009749
Putative virulence/resistance : Virulence
Product : intracellular growth locus subunit A
Function : -
COG functional category : S : Function unknown
COG ID : COG3516
EC number : -
Position : 102588 - 103142 bp
Length : 555 bp
Strand : +
Note : Several genes in Francisella necessary for replication in macrophages and for virulence including iglA, iglC, and iglD and pathogenicity determinant protein genes pdpD and pdpA, are regulated by MglA. PMID:17000729

DNA sequence :
ATGGCAAAAAATAAAATCCCAAATTCAAGGTTGATGATAAATTATGAAACTAATGTTGATGGTGTCTTAAAGAAAAAAGA
GCTACCTTACAGAGTCCTAGTTGTTGGCGATTTATCAAAAGGAAGATCTGTGGATGCAAAAAAAGAGTTCGCATATAGAG
AGGTCAGAAGAGTAAATAATGGTGTTGATAGGGTTTTAGAAGAGATGAATATATCTTTTGATTTTGAGGCACCAAACTTT
GTTTCTAAAGATCCTAGTAATTTAAAAGTTAATTATAGAATTGAAAGTGTCAAAGATTTTAGACCTGATGCTGTTGCTAA
AAAAGTTCCTGAAATCAGAGCGCTGCTTGAAATGAAAGAGATATTAGCATCCTTTGCTAAGGACATTGAAAATAATCGTA
ATCTCAAGAAAACCATAGATATGATTTTTTCAGATAGTAACGAATTAGAATCATTAAAGAGTAAGATTCCTGCTTTGACA
AATTATACGATTAAAGACTCTTGTGATGCTGCTGGGTCTCAAGACTTAAGTAATCAACAAGTAGATGGTAAGTAG

Protein sequence :
MAKNKIPNSRLMINYETNVDGVLKKKELPYRVLVVGDLSKGRSVDAKKEFAYREVRRVNNGVDRVLEEMNISFDFEAPNF
VSKDPSNLKVNYRIESVKDFRPDAVAKKVPEIRALLEMKEILASFAKDIENNRNLKKTIDMIFSDSNELESLKSKIPALT
NYTIKDSCDAAGSQDLSNQQVDGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iglA1 YP_001121162.1 intracellular growth locus, igl A Virulence FPI Protein 1e-77 99
iglA2 YP_001121565.1 intracellular growth locus, iglA Virulence FPI Protein 1e-77 99
iglA1 YP_001891778.1 intracellular growth locus protein A Virulence FPI Protein 3e-78 99
iglA2 YP_001892273.1 intracellular growth locus protein A Virulence FPI Protein 3e-78 99
iglA1 YP_170311.1 intracellular growth locus subunit A Not tested FPI Protein 2e-77 99
iglA2 YP_170619.1 intracellular growth locus subunit A Not tested FPI Protein 2e-77 99
iglA AAP58962.1 IglA Virulence FPI Protein 2e-77 98