Gene Information

Name : tkt (CBUD_0224)
Accession : YP_001423648.2
Strain : Coxiella burnetii Dugway 5J108-111
Genome accession: NC_009727
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 205650 - 207671 bp
Length : 2022 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGAGCCAACCAGTAGGAATGCCCATGCCTTCACGCCGAGACTGTGCCAATGCGATTCGTGCGTTGGCGATGGACGCTGT
TCAAAAAGCCAATTCAGGGCACCCAGGGATGCCCATGGGGATGGCAGATATTGCCGAAGTTTTGTGGCGGGATTTTTTGA
AATTCAATCCCGCTAATCTTAATTGGGTCGATCGCGATCGTTTTGTCTTATCCAATGGTCATGGCGCTATGCTGCAATAC
GCGTTGCTGCATTTGACCGGGGCCGGTTTAACCATTGAGGATATTAAACAATTTCGTCAATGGCATTCGCGCACTCCCGG
CCACCCGGAGTTCGGTGACACCCCGGGTGTGGAGACCACCACTGGGCCTCTGGGCCAAGGGCTAGCCACTGGCGTTGGCA
TGGCAATGGCTGAGCAAATGCTGGCGGCAACGTTCAATCGCGAAAATTTCCCCATCGTGGATCATTACACTTATGTTTTT
GCCGGCGACGGCGATTTAATGGAAGGTATTTCCCACGAGGCGTGTTCGTTAGCGGGGACATGGGGACTTGGCAAATTGAT
CGTCTTCTACGACGACAATGGGATTTCTATCGACGGTGAAGTCAGCGGTTGGTTCACCGACGATACGCCCAAGCGCTTTG
AAGCTTATCATTGGCATGTAGTGCCGAATGTCGACGGTCATGACCCCGATGCAATTTTGAAAGTGATTGAGGCAGCCCAA
AACGTAACGGACAAACCCAGTCTCATTTGTTGTAAAACCATCATCGGTTATGGCGCACCCATTTTAGCGGGCAAAGCTGT
CACGCATGGGGCCCCCTTAGGCGAAGAAGAAGTCGCTGGGGTTCGTAAAATTTTAAATTGGCCGCATCCGCCTTTTGAAA
TCCCCGAGGAGATTTATGCAGCGTGGGATTGTAAAGAAAAAGGCGAAAAAAACGAAACGCAATGGAATCGACTGTTTACC
GAGTACGAAAAACAGCATCCCGACTTGGCCAAAGAATTTCGTCGGCGGCAAGAAAAAGAGTTGCCGGAACAATGGGAACA
AACAGGGAAAGAGTTACTAGCAACGATGCAAGCATCAAAAGAAAATAACGCCACTCGCAAACTTTCTTTAAAATGTTTAA
ATACATTTGCGCCGTTATTGCCTGAATTAATCGGCGGCTCCGCGGATTTATCTGAATCCAATTGCACTAAATGGACGGGC
GCTACTATTCAGGGTCAGGATAATCGTTCGGGAAATTATATCGAATACGGCGTGCGTGAATTCGCCATGACGGCCATAAT
GAATGGCATGGCGCTGCATGGCGGATTTATTCCCTTCGCCGGGACCTTTTTAACTTTCTCCGATTACGCGCGCAATGCGG
TGCGGCTTGCAGCGATGATGAAAGCCCACGCTATTTTCATTTATTCTCACGATTCAATCGGTCTAGGTGAAGACGGACCG
ACGCACCAGCCGATTGAACAATTGCCTTCACTACGCATGATTCCGGGTCTGCACGTATGGCGCCCGTGCGATGGGGTGGA
AACGGCAGTGGCTTGGAAAAAGATAATCGAAGAACCGGGCGCCACCAATTGCCTTTTATTAACCCGCCAAACGGTCGCTC
ATCAAGACCGAGACGAAAAACAAATCGCTCAAATTGTCAAAGGCGGTTACATTTTGTGGGAGTCTGCTGCAAATCCCGAG
GTTATTTTAATCGCTTCGGGTTCGGAAGTGGCTGTTACGATCGAAGCTGCAAAGGCATTAGCGAAGGAAAATATTTCGGT
TCGTGTTGTTTCCATGCCCTGTTGCGAACTATTTAAAAAGCAAAACACCGATTATCGCAACTCGGTATTGCCCCCGAACG
TTAAAAAACGAGTAGCCATCGAGGCCGCTCATCCCGATTATTGGTATCAATTTGTGGGTTATGAAGGCCGAGTGATCGGC
ATTGATCGCTTTGGCGCTTCTGCGCCGTGGCAAGTGGTGTATCGTGAATATGGGTTCACGGTGGAAAATATTCTTAATGT
GGTTAATCAACTATATAAATAA

Protein sequence :
MSQPVGMPMPSRRDCANAIRALAMDAVQKANSGHPGMPMGMADIAEVLWRDFLKFNPANLNWVDRDRFVLSNGHGAMLQY
ALLHLTGAGLTIEDIKQFRQWHSRTPGHPEFGDTPGVETTTGPLGQGLATGVGMAMAEQMLAATFNRENFPIVDHYTYVF
AGDGDLMEGISHEACSLAGTWGLGKLIVFYDDNGISIDGEVSGWFTDDTPKRFEAYHWHVVPNVDGHDPDAILKVIEAAQ
NVTDKPSLICCKTIIGYGAPILAGKAVTHGAPLGEEEVAGVRKILNWPHPPFEIPEEIYAAWDCKEKGEKNETQWNRLFT
EYEKQHPDLAKEFRRRQEKELPEQWEQTGKELLATMQASKENNATRKLSLKCLNTFAPLLPELIGGSADLSESNCTKWTG
ATIQGQDNRSGNYIEYGVREFAMTAIMNGMALHGGFIPFAGTFLTFSDYARNAVRLAAMMKAHAIFIYSHDSIGLGEDGP
THQPIEQLPSLRMIPGLHVWRPCDGVETAVAWKKIIEEPGATNCLLLTRQTVAHQDRDEKQIAQIVKGGYILWESAANPE
VILIASGSEVAVTIEAAKALAKENISVRVVSMPCCELFKKQNTDYRNSVLPPNVKKRVAIEAAHPDYWYQFVGYEGRVIG
IDRFGASAPWQVVYREYGFTVENILNVVNQLYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 59
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 59