Gene Information

Name : hemC (CBUD_2170)
Accession : YP_001425472.1
Strain : Coxiella burnetii Dugway 5J108-111
Genome accession: NC_009727
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2140146 - 2141069 bp
Length : 924 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGATCAAAAAACGTAGTATTTTAATTGTCACGCGAAAAAGTCCGCTAGCATTATGGCAGGCTGAATTCGTAAAACAGCA
AATTGAAAATAGTCACCCTCACCTGGCCTGTCAAATCTTGGGGTGCACGACTCAAGGCGATCGTCTTACCACGGAAAAAT
TAGTCGACAGCGGCGGCAAAGACCTTTTTGTTAAAGATTTGCAAAAAGCATTGCTAAATCGCGATGCTGATATTGCCGTA
CATTCTATAAAAGATATGTCGGCTTGCGACGGTCCTGAATTAATGGTCGGTGCTTTTATTCGTCGCGAAGATCCACGCGA
CGTTTTAATAGTAAAGGGTGAATTATCCACTTTACCTCCTCACGCCGTCATCGGAACGTCGAGTCCACGTCGCCAATGTC
AATTGAAAAAATTTCAGCCGGGTTGCAAAATTAAAGAAATTCGAGGCAATGTCGGTACGCGATTAGCTAAACTCGACGCT
GGGCATTACGAGGCTATCGTTCTAGCGGCTGCAGGCTTAAAACGCTTAGGCTTAGAAAATCGAATCCATTATTATTTTGA
TCCTCACGAATTTATACCGGCCATCGGACAAGGCGCCATTGGTGTTGAATGTCGTTCTGATGATCATGAAATGCAAACGC
TCCTAAAATCATTGGACCATCGGGAAACTCGACTTTGTGTGACTGCGGAACGCGCTGTTAATGAAAAACTCGGCGGCGAT
TGCTTTACACCCATTGCAGCGCATGCCATCATTAAAAATGATCAACTTTCGCTGTTTGCGATGCTCGGAAAAATAGACGG
TCGCGTTATAATCCGCGCGACGGAGATTGGAAATTCAGAGGAAGCCCAAAGAATAGGTTTTAAAGTAGCATCGCAATTAT
TAGAACAGGGCGGTGATTCTCTACTGCGTGAGTTAAAACAATAA

Protein sequence :
MIKKRSILIVTRKSPLALWQAEFVKQQIENSHPHLACQILGCTTQGDRLTTEKLVDSGGKDLFVKDLQKALLNRDADIAV
HSIKDMSACDGPELMVGAFIRREDPRDVLIVKGELSTLPPHAVIGTSSPRRQCQLKKFQPGCKIKEIRGNVGTRLAKLDA
GHYEAIVLAAAGLKRLGLENRIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAERAVNEKLGGD
CFTPIAAHAIIKNDQLSLFAMLGKIDGRVIIRATEIGNSEEAQRIGFKVASQLLEQGGDSLLRELKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-58 45
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-58 45