Gene Information

Name : guaA (Xaut_0445)
Accession : YP_001415360.1
Strain : Xanthobacter autotrophicus Py2
Genome accession: NC_009720
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 487173 - 488747 bp
Length : 1575 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCTCCCCCGCTCTGGATACTGCCGCCCAGGAAACCGTCCTCATCATCGATTTCGGCAGCCAGGTGACCCAGCTCAT
CGCCCGGCGGGTGCGCGAGGAAGGGGTCTATTCCGAGGTGGTGCCGTTCCAGAAGGGCGCCGAAGCCATCCAGCGGCTGA
AGCCTAAGGCCATCATCCTCTCCGGAGGCCCCGCCTCCGTCATCGAGGGCCAGAGCCCTAAGGCGCCCGAAGAAGCCTTC
GCCGCCGGCGTGCCGGTGCTCGGCATCTGCTACGGCGAGCAGTGCATGGCGGCCCAGCTGGGAGGCGCGGTGGAGGCGGG
CCACCATCGCGAGTTCGGCCGCGCCGAGCTGACCGTCCAGAAGGTGGTGCCTCTGTTCGAGGGCGTCTGGCGCGCGGGCG
AGCGCCACACGGTGTGGATGAGCCACGGCGATCGCGTCACCGCCCTGCCCGAGGGCTTCGAGGTGGTGGCCACCTCCGAC
AACGCCCCCTTCGCCGCCATCGCCGACCTGTCGCGCAACTATTACGGCGTGCAGTTCCACCCCGAGGTGGTGCACACCCC
GGACGGCGCACGGCTGCTCTCCAATTTCGTGCGCAAGGTGGCGAAGCTCGAGGGCGCCTGGACCATGGGCGCCTTCCGCG
AGCGCGCCATCGCCCGCATCCGCGAGCAGGTGGGCACGGGGCGCGTCATCTGCGGCCTGTCCGGCGGCGTGGATTCGTCC
GTTGCGGCTGTGCTCATCCACGAGGCCATCGGCGACCAGCTCACCTGTGTGTTCGTGGACCACGGCCTGATGCGCCAGGC
CGAGGCCGACGAGGTGGTTTCGCTGTTCCGCGGCCACTACAACATCCCGCTGGTGCATGTGGACGCCTCCGAGCTGTTCC
TGAAGGAGCTGGAGGGCGTCGAGGATCCCGAGGCCAAGCGCAAGACCATCGGCCGGCTGTTCATCGACGTGTTCGATGCC
GAGGCCAGGAAGGTGGGCGGCGCCGATTTCCTCGCCCAGGGCACGCTCTATCCCGACGTGATCGAGAGCGTCTCGTTCGC
CGGCGGCCCCTCGGTGACCATCAAGAGCCACCACAATGTGGGCGGCCTGCCCGAGCGCATGAACATGAAGCTGGTGGAGC
CCCTGCGCGACCTGTTCAAGGACGAGGTGCGCGCGCTCGGCCGCGAGCTCGGCCTGCCCGAGAGCTTCGTGGGCCGCCAC
CCCTTCCCCGGCCCCGGCCTCGCCATCCGCTGCCCGGGCGCCATCACCCGCGAGAAGCTGGACATCCTGCGCAAGGCCGA
CGCCATCTATCTGGAAGAGATCCGCTATGCCGGCCTCTACGACGTGATCTGGCAGGCCTTTGCCGTGCTGCTCCCGGTGC
GCACCGTGGGCGTGATGGGCGACGGCCGCACCTACGACCACGTCCTCGCCCTGCGCGCGGTGACCTCCGTGGACGGCATG
ACCGCCGACTTCTACCCCTTCGACATGGGCTTCCTCGGCCGCACCGCTACACGCATCATCAACGAGGTAAAGGGCGTCAA
CCGCGTGGTCTACGACGTCACCAGCAAGCCCCCGGGAACAATCGAGTGGGAGTGA

Protein sequence :
MSSPALDTAAQETVLIIDFGSQVTQLIARRVREEGVYSEVVPFQKGAEAIQRLKPKAIILSGGPASVIEGQSPKAPEEAF
AAGVPVLGICYGEQCMAAQLGGAVEAGHHREFGRAELTVQKVVPLFEGVWRAGERHTVWMSHGDRVTALPEGFEVVATSD
NAPFAAIADLSRNYYGVQFHPEVVHTPDGARLLSNFVRKVAKLEGAWTMGAFRERAIARIREQVGTGRVICGLSGGVDSS
VAAVLIHEAIGDQLTCVFVDHGLMRQAEADEVVSLFRGHYNIPLVHVDASELFLKELEGVEDPEAKRKTIGRLFIDVFDA
EARKVGGADFLAQGTLYPDVIESVSFAGGPSVTIKSHHNVGGLPERMNMKLVEPLRDLFKDEVRALGRELGLPESFVGRH
PFPGPGLAIRCPGAITREKLDILRKADAIYLEEIRYAGLYDVIWQAFAVLLPVRTVGVMGDGRTYDHVLALRAVTSVDGM
TADFYPFDMGFLGRTATRIINEVKGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-131 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-131 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-131 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-120 53