Gene Information

Name : guaA (Plav_1171)
Accession : YP_001412449.1
Strain : Parvibaculum lavamentivorans DS-1
Genome accession: NC_009719
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1300992 - 1302572 bp
Length : 1581 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTACCCTCCTCAAATCCGTAGACGGGCCATGACCGAAGACCGCATTCTTATCGTCGATTTTGGAAGTCAGGTAACACA
GCTCATTGCGCGGCGCGTTCGCGAAAGTGGTGTCTATTGCGAGATCGTCCCCTTCAACAAGGCGGATGAGATGCTCGACA
CCTTCGAGCCGAAAGCGATCATTTTGTCCGGTGGTCCGGCCAGCGTCACGGTGGAGACGGGACCTCGCGCCTCCCTGCGT
GTATTCGAGCTCGGTGTTCCCGTTCTCGGCATTTGCTATGGCGAGCAGACGATGTGTGTCGAACTCGGCGGCAAGGTTGA
GGGCTCGGACCATCAGGAATTCGGCCGCGCTTCCATCGAGATCGTGGAGGAGTGCGCGCTGTTCGAGGGGCTGATGAAGG
TCGGCGACACGGAGCCGGTCTGGATGAGCCACGGCGACCGCGTCGTCGCGCTCCCGGAAGGCTTCAAGGTCGTCGCCATC
AGTCGCGGCGCTCCCTTTGCCGCCATAGCCGACGAGACAAGACGCTTCTATGGCGTTCAATTCCACCCGGAAGTGATGCA
TACGCCGCGTGGCCGCGACATGCTCTGGAATTTCACGCACAAGATTGCCGGCTGCTCCGGCGACTGGACCATGGCCGCAT
TCCGCGAAACGGAAATCGCCAAGGTGCGCGCGCAGGTCGGCAAGGGGCGGGTAATCTGCGGCCTCTCCGGCGGTGTTGAT
TCATCCGTCGTCGCCGTGCTGCTTCATGAAGCAATTGGCGATCAGCTTCAATGCGTCTTCGTCGACACGGGCATGATGCG
TGCTGGCGAAGCCGAGCAGGTCGTAAGCCTCTTCCGTAACCACTACAACATCCCGCTTGTCCATCGCGATGCGAGCGACC
TGTTCCTCGGCAAGCTCGAAGGCGTCAGCGATCCGGAGAAGAAGCGCAAGATCATCGGTGCCACCTTCATCGACGTCTTC
GAAGAAGAGGCCCGGAATATTGGCGGCGCGGATTTCCTTGCGCAGGGCACGCTCTACCCGGACGTGATCGAAAGTGTCTC
CTTCACCGGCGGCCCCTCGGTGACGATCAAGAGTCACCACAATGTCGGCGGTCTGCCCGAACGCATGAACATGAAGCTCG
TGGAACCGCTGCGCGAACTCTTCAAGGATGAAGTGCGCGAACTTGGTCGCGAACTCGGCCTGCCGCCCGATTTCGTCGGC
CGCCACCCGTTTCCCGGGCCAGGTCTTGCCATCCGCATTCCTGGCGAGATTACGCGCGAGAAACTCGAAATTCTTCGCAA
GGCCGACACCGTCTATCTCGAAGAAATCCGTTCGGCCGGTCTCTACGACGAAATCTGGCAGGCCTTCGCCGTGCTGCTGC
CCGTGCGCACCGTAGGGGTGATGGGCGATGGCCGGACCTATGACTACGTCTGCGCACTCCGCGCCGTGACATCGACCGAC
GGCATGACGGCGGACTACTATCCGTTTAGTCACGAGTTTCTTGGCCAGGTTTCCACGCGCATCATCAACGAGGTCCGAGG
CATCAACCGCGTAGTTTACGACGTAACGTCGAAACCGCCGGGGACGATCGAGTGGGAATGA

Protein sequence :
MYPPQIRRRAMTEDRILIVDFGSQVTQLIARRVRESGVYCEIVPFNKADEMLDTFEPKAIILSGGPASVTVETGPRASLR
VFELGVPVLGICYGEQTMCVELGGKVEGSDHQEFGRASIEIVEECALFEGLMKVGDTEPVWMSHGDRVVALPEGFKVVAI
SRGAPFAAIADETRRFYGVQFHPEVMHTPRGRDMLWNFTHKIAGCSGDWTMAAFRETEIAKVRAQVGKGRVICGLSGGVD
SSVVAVLLHEAIGDQLQCVFVDTGMMRAGEAEQVVSLFRNHYNIPLVHRDASDLFLGKLEGVSDPEKKRKIIGATFIDVF
EEEARNIGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRELGRELGLPPDFVG
RHPFPGPGLAIRIPGEITREKLEILRKADTVYLEEIRSAGLYDEIWQAFAVLLPVRTVGVMGDGRTYDYVCALRAVTSTD
GMTADYYPFSHEFLGQVSTRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-135 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-135 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-135 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-121 53