Gene Information

Name : leuS (Fnod_1522)
Accession : YP_001411022.1
Strain : Fervidobacterium nodosum Rt17-B1
Genome accession: NC_009718
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1649428 - 1651887 bp
Length : 2460 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAAAGAATACAAGCCACAAGAAATAGAAAGCAAGTGGCAGGGTGTTTGGTCTGAAAAAAAAGTTTTTGAAACTCCACA
GTACTCGGATAAGAAAAAGTACTATGCGCTTGTAATGTTTCCATATCCTTCTGGAACACTACATGTTGGTCACGTAAAAA
ATTACGTTATCGGTGATATAGTCGCAAGATACAAAAGAATGCAAGGGTATAATGTTCTCCATCCATTTGGTTATGATGCT
TTTGGATTGCCTGCGGAAAATGCTGCTATTGCTCACAAAATACATCCGAAAAAATGGACGTTGGACAATATCAATGTGAT
TCGTGGCCAAATAAAGAAAATAGGAATAAGTTACGATTGGAATAGAGAAGTAATAACCTGTACGGAAGATTACTACAAAT
GGACCCAGTGGGTATTCTTAAAATTATACGAAGCTGGCTTAGCATATAAGAAACCTGGTGCTGTAAATTGGTGTCCAAGT
TGTCAAACAGTTCTTGCGAACGAACAGGTAAAAGACGGAAAATGTGAAAGATGCGGTACAACAGTTACAATGAAATATCT
TGAACAATGGTATTTCAAAATAACAGACTACGCCGAAAAATTGTTGGAAGGTTTAGATAGATTACCGGGATGGCCAGAAC
ATGTTAAAACAATGCAGAGAAACTGGATAGGTAAAAGTACCGGTGCTGAAGTTGATTTCCCAGTAGATGGAATGGATAGA
AAAATAAGAATATTTACAACCAGACCGGATACGATTTACGGTGTCACATTTATGGCAATTGCCCCAGAATCACCACTTGT
AATGGAGTTGGTCACTGAAGATAAAAAGAAGGAAGTCGAAGAATTTTTAGCGAAAGTAGCTCTTGAAGATAGATTCAAAA
GAACGAGCGTTGAGGCCAAAAAAGAAGGCGTATTCTTAGGAAGATACGCGATAAATCCTTTAACAAACGAAAAAATACCA
ATTTATGTCGCAAATTATATACTTTACGAATATGGGACAGGTGCTATCATGGCTGTCCCAGCACACGACCAAAGGGACTA
TGATTTTGCGAAAACTTATAATTTGCCAATAAAACAGGTCATAAAACCAAAAGATGGCGAATGGAATATAAACGAAAGAC
CTTACGAAGAAGAAGGAATAATGATTAATAGTGGCCCATTTGATGGACTTGAAAGTTCAAAGGGTATTGAAGAAGTAACG
AAATACATTGAAGAGAAAGGTTTTGGAAAAAAGAGTGTTCAATACAAGCTTAGAGATTGGCTTATCTCAAGACAAAGATA
CTGGGGTGCTCCTATTCCCATTGTTTACTGTGAAAAATGTGGTATAGTACCTGTCCCAGAAAAAGATTTACCCGTGAGAC
TTCCAGAAAATGTCGAATTTTTACCAACGGGACAATCACCATTAACATTGAGCGAAGAATTCAAACATACAACATGTCCA
AAATGTGGAGGACCAGCTCATAGAGAAGTGGAAACGATGGATACATTTGTCGATAGTTCTTGGTATTTCCTCAGATATGT
CAACCCAAAATTAGACGACAAGCCATTTGAATCAGATGATGTGAACTATTGGTTACCTGTTGACCAATACATAGGCGGCG
TTGAACATGCAGTTCTCCACCTTCTCTACTCAAGGTTCATAACAAAAGTACTTCACGACCTCGGATACCTGAAATTCGAT
GAACCATTTGAAAATCTCTTCACACAAGGGATGATTTACAAAGATGGTTGGAAGATGAGCAAATCGAAGGGAAACGTTGT
GTCACCTGACGATATGATAAACAAGTACGGTGCAGATACACTGAGAATGTACATACTATTCATGGCACCACCTGAAAAGG
ATGCGGAATGGAATGATGCAGGCATCGACGGAGTAAATAGGTTCATAAAGAGGTTGTGGAACAATTACTACAAAATATTA
GACATAATAAACAGCAATGACACAAAAAATGAAAATGAATTTGGAAAAGAAGAGAAAAACCTTAGAAGAAAATTACACGC
AATGATAAAGAAAATAAAAGAAGACATCGAAGGTGGATTTAAATTTAATACGGCAATCGCTGGCCTTATGGAATTCAACA
ACCAACTTTCAGATTACCTTGAAAACACAAAGTCACCTAATAAAAAACTTTTAAGAGAAATTGCAGAAAAGGTTGTTTTG
ATATTATCACCATTTGCGCCACATATGGCGGAGGAAATGTGGCATGACCTTGGCAAAGAAACACTTATTGTTGAAGAAAA
ATGGCCTGAGTACGATCCAGAAGCCCTAAAGGAAGATGAATTAACTATCGTTGTTCAAGTAAATGGTAAAGTTAGAGGTA
AAATTACCGTTCCAGCGGATGCTTCTGAAGAAGAAATCAAAAACAGAGCTGTTGAAAATGCAGGTAAATTTCTTGAAGGA
AAAACTATAGTTAATACGATATACGTCAAGGGAAAATTGGTTAATATAGTAATCAAATAA

Protein sequence :
MKEYKPQEIESKWQGVWSEKKVFETPQYSDKKKYYALVMFPYPSGTLHVGHVKNYVIGDIVARYKRMQGYNVLHPFGYDA
FGLPAENAAIAHKIHPKKWTLDNINVIRGQIKKIGISYDWNREVITCTEDYYKWTQWVFLKLYEAGLAYKKPGAVNWCPS
CQTVLANEQVKDGKCERCGTTVTMKYLEQWYFKITDYAEKLLEGLDRLPGWPEHVKTMQRNWIGKSTGAEVDFPVDGMDR
KIRIFTTRPDTIYGVTFMAIAPESPLVMELVTEDKKKEVEEFLAKVALEDRFKRTSVEAKKEGVFLGRYAINPLTNEKIP
IYVANYILYEYGTGAIMAVPAHDQRDYDFAKTYNLPIKQVIKPKDGEWNINERPYEEEGIMINSGPFDGLESSKGIEEVT
KYIEEKGFGKKSVQYKLRDWLISRQRYWGAPIPIVYCEKCGIVPVPEKDLPVRLPENVEFLPTGQSPLTLSEEFKHTTCP
KCGGPAHREVETMDTFVDSSWYFLRYVNPKLDDKPFESDDVNYWLPVDQYIGGVEHAVLHLLYSRFITKVLHDLGYLKFD
EPFENLFTQGMIYKDGWKMSKSKGNVVSPDDMINKYGADTLRMYILFMAPPEKDAEWNDAGIDGVNRFIKRLWNNYYKIL
DIINSNDTKNENEFGKEEKNLRRKLHAMIKKIKEDIEGGFKFNTAIAGLMEFNNQLSDYLENTKSPNKKLLREIAEKVVL
ILSPFAPHMAEEMWHDLGKETLIVEEKWPEYDPEALKEDELTIVVQVNGKVRGKITVPADASEEEIKNRAVENAGKFLEG
KTIVNTIYVKGKLVNIVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 9e-164 43