Gene Information

Name : lysS (Fnod_1154)
Accession : YP_001410658.1
Strain : Fervidobacterium nodosum Rt17-B1
Genome accession: NC_009718
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1241787 - 1243316 bp
Length : 1530 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGCTTAAGGATTTTAGAGAAGCAAGGATTAAAGAAATAGATGAACTTCGTAATTTAGGAATTAACCCTTATCCGTATTC
TTACAATAAAACACATACAACGGAAGACATCAAAAAGCAGTTTGAACATCTTTCTAACGGTGAAGTAACCGATAAAAGAG
TTTCAACTGCTGGTAGAATAATGTCAATAAGGGAACACGGAAAAAGTGCTTTTTTCCATATAAAGGATACATATGGAAGA
ATCCAAGCTTACATTAGAAAAGACAAAACAGAGAATTACGAATTTTTCAAAGAGCGTGTCACAGTTGGTGATATAGTTGG
TGTTGAAGGTATAGTATTTAAGAGCAATACTGGTGAAATCACCATACTTGTGGAAAAGTTTGAACTTCTGGTTAAACCTT
TAAGACCAATGCCTGAAAAATGGCACGGTATAAAGGACAAGGAAGTACTTTACAGGCAAAGATATGTTGATATGATTGCA
AACGACGAAACAATTAAGAGATTTAGAATGAGATCGGATATTATAAGGATGATTAGAGAGTTTCTTACAAAGAAAGGATT
TTTTGAAGTTGAAACGCCAATACTTCAATACCTTACGGGTGGTGCATCTGCAAGGCCATTTATTACACATTTAAATGCTC
TTGATATAGACATGTATCTTAGAATTGCCACGGAATTACACCTTAAGAGATTTATAGTCGGAGGTTTTGATAAGGTTTAC
GAGATTGGTAAAATATTCAGAAACGAAGGGATTTCCTACAAACATCACCCAGAATTTACATCAATAGAACTTTATCAAGC
TTACGCTGATTACGAAGATATGATGAACCTTACGGAAGAACTTATAACATACCTTGTTGAGCAACTATACGGTACAACTA
AGATAACATATCAAGGTCAAGAGATTGATTTTACAAGACCTTGGAGAAGAGTAAAGATGAGAGATTTCATAAAAGAAAAT
CTTGGTGTTGATATCATAGAAGATAGTGATGAAACAATGGCAAAAGTGCTTGCAGAAAATGGAGTGGAAGTTGATATAAA
CGATAGAGGCCATATGATAGAGAAACTTTGGGATCTTGTTGAAGACAAAGTTATTCAACCAACGTTCTTACTCGAACATC
CTGTTGAAATATCACCACTTGCCAAAAAGCACAGAGAAGATCCAAGGGTAACGGAAAGATTTGAACTTATAATTTATGGT
AGAGAAATGGCCAATGCATTCAGTGAATTGAACGATCCTGTTGACCAACTTGAAAGATTTATGAACCAACTGAGACTTAG
AGACCTTGGCGATCAGGAAGCTCAAATGCTAGATAAAGACTTTGTAAGAGCTCTGGAATATGGAATGCCACCAACTGGAG
GACTCGGAATAGGAATAGATAGATTGGTAATGCTGCTTACAGACAGTGCTAATATAAGGGACGTTATAGCATTCCCACTT
GTGAGACCAGAAGGAGATATAGATATTGAAGATTACACCGATTTAGAAAAATCTGAAATCATAGAAAAAGAAGGGGGAAA
TAAAGCATGA

Protein sequence :
MLKDFREARIKEIDELRNLGINPYPYSYNKTHTTEDIKKQFEHLSNGEVTDKRVSTAGRIMSIREHGKSAFFHIKDTYGR
IQAYIRKDKTENYEFFKERVTVGDIVGVEGIVFKSNTGEITILVEKFELLVKPLRPMPEKWHGIKDKEVLYRQRYVDMIA
NDETIKRFRMRSDIIRMIREFLTKKGFFEVETPILQYLTGGASARPFITHLNALDIDMYLRIATELHLKRFIVGGFDKVY
EIGKIFRNEGISYKHHPEFTSIELYQAYADYEDMMNLTEELITYLVEQLYGTTKITYQGQEIDFTRPWRRVKMRDFIKEN
LGVDIIEDSDETMAKVLAENGVEVDINDRGHMIEKLWDLVEDKVIQPTFLLEHPVEISPLAKKHREDPRVTERFELIIYG
REMANAFSELNDPVDQLERFMNQLRLRDLGDQEAQMLDKDFVRALEYGMPPTGGLGIGIDRLVMLLTDSANIRDVIAFPL
VRPEGDIDIEDYTDLEKSEIIEKEGGNKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 9e-99 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001410658.1 lysyl-tRNA synthetase VFG1668 Protein 5e-99 45