Gene Information

Name : guaA (CCV52592_0940)
Accession : YP_001407808.1
Strain : Campylobacter curvus 525.92
Genome accession: NC_009715
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 531692 - 533224 bp
Length : 1533 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAACAACACTATTATTGTTTTGGACTTTGGCTCGCAATACACTCAGCTCATCGCTCGCAGACTGCGTGAACAAGGCGT
TTATACTGAAATTTTGCCATTTAGCGTAAAGCTTGACGAGATCAAGGCAAAAAAGCCAAAAGGTATCATCCTTAGCGGCG
GACCGGCGAGCGTTTATGCCAGCGACGCGTATTTTTGTGATGAAGGGATTTTTAAGCTTGGTTTGCCGGTGCTTGGTATC
TGCTACGGCATGCAGCTCATGGCTCACGTCTTTGGCGCACAGGTCGCTCCCGCCAGCCAGAAAGAATACGGCAAGGGCGA
GCTAAATTTACTAAAATCTCATCCGCTTTTTACCGACACGCCCCAAAAGCAAATCGTCTGGATGAGCCACGCTGACTACG
TAAAAAACCTGCCAAACGGCTTTGAGGCGCTCGCTATCAGCGAGAATTCGCCTTACTGCGTTTTTGGCGATGACAAGCGT
AAATTTTATGCGTTGCAGTTTCATCCAGAAGTGCAACACAGCGAGTTTGGCACGCAAATTTTGAAAAATTTCGCCAAATT
TATCTGCGGATGTGAGAGCACGTGGAATATGGGCAGCTTTGCTAAAACTCAAATCGCCAAGATAAAAGAGACCGTTGGCA
ACAAAAAGGTGCTTTGTGCGGTGAGCGGCGGCGTGGATAGCTCCGTCGTGGCGGCACTTCTAGCAGCTGCGATACCGCAA
AATTTGATACTTGTTTTTGTGGATAACGGGCTTTTGCGCACAGGCGAGCGTGAGCAGGTCGAGGCGACGTTTAGGACGAA
GCTTGGCGTGGAGCTGGTTAGCATCGACGCGAGTAAAATTTTCTTAGAGCGCCTTGCTGGCGTGGTCGAACCCGAGAAAA
AGCGCAAGATCATTGGCGAGACGTTTATCGAAATTTTTGAAAAAGAGGCAAAAAAGCACGATAATGTGAAATTTCTCGCG
CAAGGCACGCTTTATACCGACATCATCGAAAGCTCGGTCGTGGGCGCTGGAAAGACGATAAAAAGCCATCATAACGTAGG
CGGGTTGCCAGAGTGGATGAGCTTTGAGCTGATTGAGCCATTGCGCGAAATTTTTAAAGATGAAGTGCGTCAGCTAGGGC
TTGAGCTTGGGCTTTCAAAGGAGCTAGTTTTCCGTCATCCTTTCCCGGGACCGGGGCTTGCCATACGCATAATGGGCGAA
GTGAATACTCCAAGTCTCGAACTACTACGCAAAGCCGATGTGATCTTGCGCGACGAGCTAAAAAGTAGCGGCTGGTATAA
TAAGACGTGGCAGGCGTTTTGCGTGCTATTAAATGTAAATTCCGTAGGCGTCATGGGCGATAACCGCACGTATGAAAATG
CCGTTTGCGTGCGCGTCGTGGATGCGAGCGACGGCATGACGGCAAGCTTCTCGCGACTGCCATACGAACTACTGGAAAAC
ATCTCTCGCCGCATCATCAACGAAGTAGTAGGCATCAACCGCGTCGTGTATGACATCTCGAGCAAGCCACCTGCGACGAT
AGAGTGGGAGTAA

Protein sequence :
MNNTIIVLDFGSQYTQLIARRLREQGVYTEILPFSVKLDEIKAKKPKGIILSGGPASVYASDAYFCDEGIFKLGLPVLGI
CYGMQLMAHVFGAQVAPASQKEYGKGELNLLKSHPLFTDTPQKQIVWMSHADYVKNLPNGFEALAISENSPYCVFGDDKR
KFYALQFHPEVQHSEFGTQILKNFAKFICGCESTWNMGSFAKTQIAKIKETVGNKKVLCAVSGGVDSSVVAALLAAAIPQ
NLILVFVDNGLLRTGEREQVEATFRTKLGVELVSIDASKIFLERLAGVVEPEKKRKIIGETFIEIFEKEAKKHDNVKFLA
QGTLYTDIIESSVVGAGKTIKSHHNVGGLPEWMSFELIEPLREIFKDEVRQLGLELGLSKELVFRHPFPGPGLAIRIMGE
VNTPSLELLRKADVILRDELKSSGWYNKTWQAFCVLLNVNSVGVMGDNRTYENAVCVRVVDASDGMTASFSRLPYELLEN
ISRRIINEVVGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-136 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-116 50