Gene Information

Name : lysS (CCV52592_1349)
Accession : YP_001407789.1
Strain : Campylobacter curvus 525.92
Genome accession: NC_009715
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 511877 - 513388 bp
Length : 1512 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGATATTTGACAACCAACTAGAAATCCAAAGGCTTGAAACGGCTGAAAATTTAAGAAAAATGGGCGTAAATCCATACCC
GCACTTTCTAAGACGCGATATGGACATAGCAAAATTTAGGCTCAAATTCGCTCACATCATAAACACCGAAGACAAAAAAG
CCGAAGGGCAGTATGTGAGCCTCGCCGGTCGTATCAAGCTCATTAGAGACGCCGGCAAAGCGATATTTGCAAATATCGAG
GACGAAAACGGAAATTTACAAATTTATTTTAGCAATAAAACACTTGATTCGGAGTGGTTTAAGGTCGTAAAGAAAAACAT
CGAAGTTGGCGACATCATCTATGTGCGCGGCTATGCTTTCGTGACGCGAACGGGTGAGTTTTCGATGCATGTTAGCGAGC
TAAATTTAGCCTCCAAGGCGATCTCGCCTTTGCCTGAGAAATTTCACGGACTCGTGGATATCGAGACTCGCTACCGACAA
AGATACCTTGATCTAATAATGAATCCTGAGGTCAGAAGCGACTTCAAAAAGCGCTCCATCATCATCAGCACCATACGCCG
ATTTATTGAAGAGAAGGGCTTTTTAGAGGTCGAGACGCCGATGATGCACCCGATCGCCGGCGGTGCGAACGCAAAGCCGT
TTGTCACCTTTCACAACGCCCTTGGTGTCAATAGATACCTTCGTATCGCGCCCGAGCTTTATCTAAAACGCCTCATCGTG
GGTGGCTTTGAAGCCGTTTATGACATGAATAGAAATTTTAGAAACGAGGGCATGGATCTAACGCACAATCCTGAATTTAC
AAGCATAGAATTTTACTGGGCGTATCACACATATCACGATCTAATGGGGCTAACAGAGGAGCTATTTAACGTGCTCATCG
ACAAGCTAGATCTACCAAAGGTCATTGAATTTGACGGTATGCAGGTTGATTTTAGCAAGCCGTTTGCGAGGCTAAACTAC
AAAAAAGCACTCGTCGAGGTGGGCGGACTAGACCCGCAGATCATAGAGGATAAAGATAAAATTTTAGCCAAGCTTAAAGC
GGACGGCTTTGAAGCGAATGCAAAGCTCGATCTCGGGCATTTGCAAGCCGAGCTTTTTGATAACTACGTCGAAGAAAAGC
TCATAGATCCGACCTTCATCATCGACTATCCGATCTCGATCAGCCCGCTTTCAAGAAGGAGCGACAAAAACCCTGAAATA
GCCGAAAGATTTGAGCTGTTTATCGCCGGACGAGAGCTGGCAAATGGCTTTAACGAGCTAAACGACCCGGTTGATCAGTA
TAACCGCTTTGCCGCCCAGATCGAGGCTAAAAATGCAGGCGATGACGAAGCGCACGAGATGGACGAGGACTACGTTAGAG
CACTTGGATACGCGATGCCGCCGACTGCGGGCGAGGGTATCGGCATAGACCGCCTCGTGATGCTATTAACAAATAAAAAA
TCTATCCGCGACGTGGTGCTTTTTCCTGCGATGCGTCCGCTAAAAAGTGAAATAAAGGAGAATGAAAAATGA

Protein sequence :
MIFDNQLEIQRLETAENLRKMGVNPYPHFLRRDMDIAKFRLKFAHIINTEDKKAEGQYVSLAGRIKLIRDAGKAIFANIE
DENGNLQIYFSNKTLDSEWFKVVKKNIEVGDIIYVRGYAFVTRTGEFSMHVSELNLASKAISPLPEKFHGLVDIETRYRQ
RYLDLIMNPEVRSDFKKRSIIISTIRRFIEEKGFLEVETPMMHPIAGGANAKPFVTFHNALGVNRYLRIAPELYLKRLIV
GGFEAVYDMNRNFRNEGMDLTHNPEFTSIEFYWAYHTYHDLMGLTEELFNVLIDKLDLPKVIEFDGMQVDFSKPFARLNY
KKALVEVGGLDPQIIEDKDKILAKLKADGFEANAKLDLGHLQAELFDNYVEEKLIDPTFIIDYPISISPLSRRSDKNPEI
AERFELFIAGRELANGFNELNDPVDQYNRFAAQIEAKNAGDDEAHEMDEDYVRALGYAMPPTAGEGIGIDRLVMLLTNKK
SIRDVVLFPAMRPLKSEIKENEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-99 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001407789.1 lysyl-tRNA synthetase VFG1668 Protein 2e-99 48