Gene Information

Name : tkt (CCV52592_0069)
Accession : YP_001409120.1
Strain : Campylobacter curvus 525.92
Genome accession: NC_009715
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1875013 - 1876923 bp
Length : 1911 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCTGAAAAAACAAGCCGATACGATAAGATTTTTGTGTGCCGATATGGTGCAGGCGGCAAATTCCGGTCATCCGGGCGC
TCCGATGGGGATAGCCGATATAATGGTCGTCCTCTCGAAACACCTAAAACACAACCCCAAAGATCCTACCTGGCTAAACC
GCGACAGGCTCGTTTTTAGCGGGGGACACGCGAGTAGCCTCGTTTATAGCTTTTTATATCTTAGCGGCTACGACGTGAGC
CTTGAGGATCTTAAAAATTTCCGCCAGCTTGGCTCAAACACCCCCGGTCATCCTGAAATTCACACTCCGGGCGTCGAGAT
AGCCACCGGGCCTTTAGGTCAAGGCGTGGCGAACGCAGTAGGCTTTGCCATGGCGGCAAAATACGCTGCGAATGTCCTAA
ATACGCCTGAAAACGAGATAATAAACCATAAAATTTACTGCCTTTGCGGAGACGGAGACCTGGAGGAGGGCATAAGCTAC
GAGGCATGTGCCTTGGCCGGGCGCTTGGGCCTTGATAACCTGGTGATGATATATGACTCAAACCACATCACGATCGAGGG
CGATACGGCCATAGCTTGGAGCGAAGACGTGAAGGTCAGGTTCGAGGCGCAAGGCTTTGAGGTCGCACGCATAAACGGGC
ATGATTACGACGAGATAGAATTTGCCCTAAGCGAGGCGGCAAACAAAGACAAGCCCTATCTCATCATCGCAAATACCAGC
ATCGCAAAAGGTGCGGGCGAGCTTGAAGGCAGTCATAACGCGCACGGTGCGCCGCTTGGCGAAGAGGTCATACGCGCGGC
AAAGAGCGCGGCGGGCTTTGATCCGGAGCTTAAATTTCATGTCGATGAGGATGTACTTATTAGATTTCGTGTGGCTCTTG
AGAGAGGAGATCTCGCACAGGCCGAGTGGAACAAGCAACTCTTGTCGCTAGATGATGAAAAGGCTGAAATTTTAAACGGG
CTTTTAAACCCGGATCTAAGCACGATAGAGTATCCTAAATTTGACGGTAAAAAGCTAGCCACACGCGATAGCAACGGGCA
GATAATAAACGCTATCGCAAGCGCGCTACCCGGATTCATCGGTGGCAGCGCAGATCTAGCACCGTCAAACAAGACCGAGC
TAAAGGGTATGGGCGACTTCCCGTGCGGCAAGAACATACACTTTGGCATCCGCGAGCATGCGATGGCGGCGATAAATAAC
GCGTTTGCCAGATACGGGCTGTTTTTGCCTTTCTCGGCGACGTTTTTTATTTTCAGCGATTATCTAAAGCCAAGTGCCAG
GATGGCTGCTCTCATGAGCCTAAAGCACTTTTTCATCTTTACGCACGATAGTATCGGTGTGGGCGAAGACGGTCCGACGC
ATCAGCCTATCGAGCAGCTAAGCCAGTTTCGCGCGATGCCAAATTTCTATACCTTCCGTCCGGCTGACGGCAACGAGAAC
GTCCTTTGCTGGCAGGCGGCTCTAAATTTAGACGCTCCAAGCGCGTTCGTGCTTTCTCGTCAAGGGCTTGCACCGCTTGA
GGGCGGAGTCTTTGGCGAGGTCAAAAACGGAGCGTATCTGCTAAAAAAGAGTGAAAACGCGAAGATCACCTTTGTCGCAA
GCGGCAGCGAGGTCGAGCTTTGCCTCAAAGCGCATGAAATTTTAAGCGGCGATGGCATAGCTACGAATGTAGTTTCGGCA
CCTTGCTTCGATCTGCTTTGCGAGCAGTCAGGCGAATATCTGAATAAAATTTTAGACAAAAATAGCGTCGTGATCGCCGT
AGAGGCTGCAAGAGGGCTTGAGTGGTTTAAATTTGCAGATCATGTTTACGGTATGAAAGGCTTTGGCGCTTCAGGCAAAG
CCGCAGAGCTGTTTAGCCATTTTGGCTTCGAGCCGACTGCGCTAAGCGAATTTGCAAAAGGTGTGCTTTAA

Protein sequence :
MLKKQADTIRFLCADMVQAANSGHPGAPMGIADIMVVLSKHLKHNPKDPTWLNRDRLVFSGGHASSLVYSFLYLSGYDVS
LEDLKNFRQLGSNTPGHPEIHTPGVEIATGPLGQGVANAVGFAMAAKYAANVLNTPENEIINHKIYCLCGDGDLEEGISY
EACALAGRLGLDNLVMIYDSNHITIEGDTAIAWSEDVKVRFEAQGFEVARINGHDYDEIEFALSEAANKDKPYLIIANTS
IAKGAGELEGSHNAHGAPLGEEVIRAAKSAAGFDPELKFHVDEDVLIRFRVALERGDLAQAEWNKQLLSLDDEKAEILNG
LLNPDLSTIEYPKFDGKKLATRDSNGQIINAIASALPGFIGGSADLAPSNKTELKGMGDFPCGKNIHFGIREHAMAAINN
AFARYGLFLPFSATFFIFSDYLKPSARMAALMSLKHFFIFTHDSIGVGEDGPTHQPIEQLSQFRAMPNFYTFRPADGNEN
VLCWQAALNLDAPSAFVLSRQGLAPLEGGVFGEVKNGAYLLKKSENAKITFVASGSEVELCLKAHEILSGDGIATNVVSA
PCFDLLCEQSGEYLNKILDKNSVVIAVEAARGLEWFKFADHVYGMKGFGASGKAAELFSHFGFEPTALSEFAKGVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-109 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-101 42