Gene Information

Name : hemC (CHAB381_0899)
Accession : YP_001406461.1
Strain : Campylobacter hominis ATCC BAA-381
Genome accession: NC_009714
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 836624 - 837550 bp
Length : 927 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAATAAACTCAGAATAGCAACAAGAGGCTCAGCTTTGGCGCTTTGGCAAAGTAAATACATACAAAATTTAATCGAAAA
TAACACTGAAGTTGAAGTTGAACTTCAAAGTATGAAAACAAAAGGCGATGTCATACTTGATACACCGCTTGCAAAAATCG
GCGGCAAGGGGCTTTTTACAAAAGAATTAGAAGAAAGTATGTTAAGAGGTGAAAGCGATTTGGCAGTTCACAGCTTAAAA
GATGTTCCTGTAGTTTTTCCAAAAGGTCTTATTTTAACGGCAATCAGTGAAAGAGAAGATGTAAGAGATAGCTTTGTAAG
TGAAAAATTTGCAAGTTTTAATGAACTTCCAAAAGGCGCAAAAGTAGGCACAACTTCACTTAGAAGAAAAATGCAGCTTC
TTATAAAACGTCCCGATTTGAAAATCATTTCGCTTCGCGGAAATATAAATACCAGACTTAGAAAATTAAAAGAGAATGAG
TTTGACGCGATAATTCTTGCAAGTGCCGGACTTAAAAGGCTTAATCTTATGGAAAATATAAAATATTTCGTGCCGTTTTC
GCTCGATGAGATGATTCCTGCGATGGGTCAAGGCGCACTCGGAATAGAGTGTGTGGATAAAAGCGAAGTTATAGAAATTT
TAAAATTTATAAATAATGAAAATTCCGTTATCGCAACAACGATAGAGCGCGATTTTGTAGCTAAATTAAACGGCGGCTGC
CAAGTTCCGATTGGTGTAAATGCTGAAATTTCAGGCGATATAATCAAAGTAAGAGCTATTGTCGGACTTCCTGATGGAAG
CGAGTTTATAAAAGACAAGCGCGAAATTTCAAAAGCCGATTTTAAAAATTTTGGAACTAAATTGGCCGATGAATTTATCT
CGCGCGGCGCAATAGAGCTTTTAAAACGCGCAGAGGAAATGGCGTAA

Protein sequence :
MNKLRIATRGSALALWQSKYIQNLIENNTEVEVELQSMKTKGDVILDTPLAKIGGKGLFTKELEESMLRGESDLAVHSLK
DVPVVFPKGLILTAISEREDVRDSFVSEKFASFNELPKGAKVGTTSLRRKMQLLIKRPDLKIISLRGNINTRLRKLKENE
FDAIILASAGLKRLNLMENIKYFVPFSLDEMIPAMGQGALGIECVDKSEVIEILKFINNENSVIATTIERDFVAKLNGGC
QVPIGVNAEISGDIIKVRAIVGLPDGSEFIKDKREISKADFKNFGTKLADEFISRGAIELLKRAEEMA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-66 51
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-66 51