Gene Information

Name : smpB (CHAB381_1111)
Accession : YP_001406667.1
Strain : Campylobacter hominis ATCC BAA-381
Genome accession: NC_009714
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1044014 - 1044475 bp
Length : 462 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAAAGAACTGACAAAAAATAAAAAAGCGTGGCATAATTTTACGATAATAGAAAATTTTGAAGCCGGAATTGTGCTTAA
AGGTAGCGAAGTAAAAGCATTAAGAATGGGGCGTGCAAACCTGAAAGACAGCTTTTGCAGAATCATCAAAGGAGAACTTT
TTTTATTAAACGCTCACATCAGTTTTTTGGAAAATACAAATGCATTTTTTCGTCCAAGCGAAAACGGCGCAAGAAAACTT
TTAATGCATAAAAAAGAGATAAACAGACTTTTTGGCGCCGTTTCAAAAGAAGGTATGGCGATTGTGGCGCTATCGCTTTA
TCTAAACGACAAAAACAAAGTAAAAGCGCGAATCGCGCTTGCGAAAGGCAAAAATCTGCACGATAAAAGAGAGGCTTTAA
AACGAAAAGAAGCCGAACGTGAAGCACAAAGCGCGATGAAAAGATATGCAAAAGGATACTGA

Protein sequence :
MKELTKNKKAWHNFTIIENFEAGIVLKGSEVKALRMGRANLKDSFCRIIKGELFLLNAHISFLENTNAFFRPSENGARKL
LMHKKEINRLFGAVSKEGMAIVALSLYLNDKNKVKARIALAKGKNLHDKREALKRKEAEREAQSAMKRYAKGY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-20 44
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 8e-19 43