Gene Information

Name : Mboo_1991 (Mboo_1991)
Accession : YP_001405148.1
Strain : Methanoregula boonei 6A8
Genome accession: NC_009712
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 2054429 - 2055589 bp
Length : 1161 bp
Strand : +
Note : PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cystathionine gamma-lyase

DNA sequence :
ATGAAGTTTGAGACCGCCGCAGTGCATGCCGGAGAAGAACCGGCCTTTTCCGAGGGGGCATCAGGAGACGTTGTAATTCC
CATTCACCTCTCGTCCACATTTGCACGCGTAGACGTGGCAAAACCGACCGGAGGATATGAATATTCCCGGAGCAGTAACC
CGACGCGTCTGGCACTCGAACAGAAACTGGCGGCAATCGAGGGTGCACGCTTTGGTTTGGCGTTCTCCTCAGGACTTGCC
GCGGAAACCACCGTAGCCCTCTCCCTGCTCAAAAAGGACGAACACGTAGTTGCATTCGATGATCTCTATGGAGGCACACG
AAGACTCTTTACCCGGGTGTTCCAGGAAAACTACGGGATTGACTTCTCTTACGTGGATGCACGGGATGCGGAGAATGTGA
AATCCGCACTCCGGAAAGACACCCGTTTTGTCTGGCTGGAGAGCCCCACCAACCCCCTCATCCGGCTCTGTGACATCCGG
GAGATTGCCGGGATCGCCCACGATGCTGGAGCGCTTGTGATCGTGGACAATACCTTTGCAAGCCCGTACTTCCAGCACCC
GCTTGCGCTCGGTGCGGATATCGTGGTCCACAGCACAACCAAGTACATCAACGGCCATTCGGACTCAGTGGGTGGGGCCG
TGATGCTCTCTGAAGAAGACCTGTACCAGCGGATCCGGTACAACCAGAACGCTGCAGGTGGCATCCTCTCACCTTTCGAC
AGTTTCCTTGTTGCACGGGGCATAAAGACGCTCGCCCTGCGGATGGAACGGCACCAGAAAAATGCCCTTACTCTTGCAAA
GTACTTTGAAGGGCACGAAAAAATCAGCGCCGTCTACTATCCGGGCCTCCGCACCCATCCGCAATATGCGCTTGCCAAAA
AGCAGATGGACGGATTCTCCGGTATGATTTCCTTTGAGGTTAAGGGAGAAGGGAAGGCTGCGCTCAGATTCCTGCGCTCC
CTCTCTCTCTTCGCGCTTGCCGAGAGCCTCGGAGGGGTTGAATCGCTGATTGAACACCCGGCAAGCATGACCCATGCCTC
TATCCCGAAACACGAGCGGGAGAAGGTAGGGGTGACCGACTCGCTCATCCGCGTATCGGTTGGCATTGAGAATGTAAAGG
ATCTTGTCGATGACCTGGAACAGGCATTTGAAGAGATCTGA

Protein sequence :
MKFETAAVHAGEEPAFSEGASGDVVIPIHLSSTFARVDVAKPTGGYEYSRSSNPTRLALEQKLAAIEGARFGLAFSSGLA
AETTVALSLLKKDEHVVAFDDLYGGTRRLFTRVFQENYGIDFSYVDARDAENVKSALRKDTRFVWLESPTNPLIRLCDIR
EIAGIAHDAGALVIVDNTFASPYFQHPLALGADIVVHSTTKYINGHSDSVGGAVMLSEEDLYQRIRYNQNAAGGILSPFD
SFLVARGIKTLALRMERHQKNALTLAKYFEGHEKISAVYYPGLRTHPQYALAKKQMDGFSGMISFEVKGEGKAALRFLRS
LSLFALAESLGGVESLIEHPASMTHASIPKHEREKVGVTDSLIRVSVGIENVKDLVDDLEQAFEEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-75 46
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-74 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-61 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mboo_1991 YP_001405148.1 cystathionine gamma-lyase BAC0207 Protein 2e-60 42