Gene Information

Name : Mboo_0144 (Mboo_0144)
Accession : YP_001403311.1
Strain : Methanoregula boonei 6A8
Genome accession: NC_009712
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 138405 - 140714 bp
Length : 2310 bp
Strand : +
Note : PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: bam:Bamb_4345 lysine decarboxylase

DNA sequence :
ATGAGTTCCCCAGAGCGGCTTGTTGTTGCGGTCATAGATGACGAGATCCATAAGGATACCCCTCATGGCAGGGCGATCAA
ACGGATTATCCGCGACCTTGAAAAATATGAGATTTTTGTTGCCGATATTGCCTCGCCTGAGGATGCACGAACCGCGTATT
CCAACCTCCCCTCGGTCAACTGCATCCTCATCGACTGGAACCTGGGTAACCGGGAGAAGGAGGCACAGCAGGACACGCTC
AAACTGATCCGGCAGATCCGCTGCATCAACGAAGATCTCCCGATCTTCCTCATGGCAGAGCCCACAAGCGAGCCACCGAT
CGGGATCACGGTGGATGTACTCAAGGAGATTAACGAGTACCTCTACGTGATGGAGGACACCTCCGAGTTTATCGCCGGGC
GTATCTCGGCTGCAGCAAAGCGGTACCAGGACCGGCTGCTGCCGCCGTTTTTCGGGGAACTCGTGAAGTTCTCCAAGGAT
TTCGAGTATTCCTGGCACACGCCGGGCCATGCCGGTGGGACAGCGTTCCGCAAGACGCCCGCCGGGCGGCGGTTTTTCGA
ATTCTTCGGCGAACAGCTCTTCCGGTCCGATCTCTCCATCTCGGTCGGGGAGCTTGGCTCGCTTCTCGACCACTCCGGGC
CGGTGGGCGAAGCCGAACGGTACGCCGCAAAGGTCTTCGGGGCCGACATGTCCTATTTTGTGACAAACGGTACTTCAACG
GCAAACAAGATCGTCTTTTTTGGCCGGGTTACCGAGAACGATGTTGTCCTTGTGGACCGGAACTGCCACAAATCGGCCGA
GCATGCGCTCACCATGACTCACTCTGTCGCCGTGTACATGGTCCCGACCAGGAACCGGTACGGGATCATCGGCCCGATCC
CGCCCTCCGATATGACACCGGCAGCTATCAGGAAAAAGATCGCTGCCTGCCCCTTAGCAAAAAACCTTCCCGACAAAACC
CCGGTCCACGCGATTGTCACCAACTCGACCTATGACGGCCTCTGCTACCATGCGGTGGAAGTGGAAAAGGAACTGGGAAA
AAGCGTTGACAGCATCCATTTCGATGAGGCATGGTACGGCTATGCCCGGTTCAACCCGCTCTACCGCGACCGGTTTGCCA
TGCGGGACGGGGCAAAGGACAAGAAAGGCCCGACCGTCTTTGCCACCCAGTCAACCCACAAACTGCTCGCCGCGCTCTCG
CAGGCGTCCATGGTCCATGTAAGAAACGGCCGTGTCCCGATCGAGCATGCCCGGTTCAACGAGGGGTTCATGATGCACAG
CTCCACGTCCCCGCTCTACACGATCATCGCATCGCTGGACGTGTCCACCAAGATGATGGACGGGGCATCAGGAAGGCTGC
TCACGACCGAGTCAATCGAGGAAGCAATCCGGTTCCGCCGCACGATGGCAAGAATCGAAAAGGAGATCGGGACCGGCAAG
ACCAGGACCGACTGGTGGTTCCCCATGTGGCAGCCGGACACCGTCACGGATCCGAAAACCAAAAAGAAGATCGCGTTTGC
CACGGCACCCCTGGAGACCCTGCGGGATAACCCCTCGTGCTGGGTGCTGCACCCGAAGGATGCATGGCATGGCTTTGAGG
ACCTGCCCGACAACTACTGCATGCTCGATCCCATCAAGGTGACCGTGCTCACGCCCGGCGTCAAAGAGGATGGATCGCTT
GCTGCATGGGGCATCCCGGCAGCCATTGTTGTCAAGTTTTTGGACACCCGGGGCATCATCAATGAGAAGTCCGGGGATTA
CTCGATCCTCTTCCTCTTCTCGATGGGGATCACGAAAGGCAAGTGGGGTACCCTTATTACCGAGCTCTTCGAGTTCAAAC
GCCGTTACGATGAGAACGCCCCGCTTGACGAGGTCTTCCCTGACCTTGTGGCACAGTGGCCGGATCGGTACGGCGGCATG
ACCCTGCCGGAGCTTGCGGCCCAGATGCACGCGTTCAAGCGCGACCACAACATGTGTGGATTGCTCCAGAAAGCGTTCTC
GGCCCTTCCGGAGCCGGTGATCACGTACGCGGAATCCTACAAGAGACTCGTGCGGGACGAGGTAGAGCAGATACCGGTTG
CGCAGGCGGCAAACCGCATCGTGGCAACAGGTATCGTGCCCTACCCGCCGGGCATCCCGCTGCTTGCACCTGGCGAGAAG
ACCGGGCCAAAGACCGGCCCGGTGCTCCAGTACCTGCTCTCGCTGCAGGATTTTGACCGGCGCTTCCCCGGCTTTGAGCA
CGACACCCACGGGATCGAGAGCATCAAAGGTGAATACAGGATGATCTGTGTAAAGGAGAAGAAACGATGA

Protein sequence :
MSSPERLVVAVIDDEIHKDTPHGRAIKRIIRDLEKYEIFVADIASPEDARTAYSNLPSVNCILIDWNLGNREKEAQQDTL
KLIRQIRCINEDLPIFLMAEPTSEPPIGITVDVLKEINEYLYVMEDTSEFIAGRISAAAKRYQDRLLPPFFGELVKFSKD
FEYSWHTPGHAGGTAFRKTPAGRRFFEFFGEQLFRSDLSISVGELGSLLDHSGPVGEAERYAAKVFGADMSYFVTNGTST
ANKIVFFGRVTENDVVLVDRNCHKSAEHALTMTHSVAVYMVPTRNRYGIIGPIPPSDMTPAAIRKKIAACPLAKNLPDKT
PVHAIVTNSTYDGLCYHAVEVEKELGKSVDSIHFDEAWYGYARFNPLYRDRFAMRDGAKDKKGPTVFATQSTHKLLAALS
QASMVHVRNGRVPIEHARFNEGFMMHSSTSPLYTIIASLDVSTKMMDGASGRLLTTESIEEAIRFRRTMARIEKEIGTGK
TRTDWWFPMWQPDTVTDPKTKKKIAFATAPLETLRDNPSCWVLHPKDAWHGFEDLPDNYCMLDPIKVTVLTPGVKEDGSL
AAWGIPAAIVVKFLDTRGIINEKSGDYSILFLFSMGITKGKWGTLITELFEFKRRYDENAPLDEVFPDLVAQWPDRYGGM
TLPELAAQMHAFKRDHNMCGLLQKAFSALPEPVITYAESYKRLVRDEVEQIPVAQAANRIVATGIVPYPPGIPLLAPGEK
TGPKTGPVLQYLLSLQDFDRRFPGFEHDTHGIESIKGEYRMICVKEKKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 3e-124 43
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 1e-126 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mboo_0144 YP_001403311.1 lysine decarboxylase VFG1670 Protein 2e-124 43