Gene Information

Name : thyA (YpsIP31758_0984)
Accession : YP_001399968.1
Strain : Yersinia pseudotuberculosis IP 31758
Genome accession: NC_009708
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1177175 - 1177969 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTGGATTTGATGAAAAAAGTGCTGGAAGAAGGCACACCTAAAGCTGACCGTACCGGTACCGGCACTCT
GTCAATTTTTGGGCATCAGATGCGTTTCAATTTACAAGACGGTTTCCCATTGGTCACCACCAAGCGTTGCCACCTACGTT
CGATTATCCATGAGTTGTTATGGTTCCTGAATGGCGATACCAACATTGCTTATCTGAAGGAAAATAATGTCTCAATCTGG
GATGAATGGGCAGATGAAAACGGCGATCTTGGTCCGATTTATGGTAAACAATGGCGTGCTTGGGGGGCTGCTGATGGCCG
AAAAATTGACCAGTTGAGTAACGTAGTCAATCAACTGAAGCAGGACCCTGATTCGCGCCGGATTATTGTTTCTGCGTGGA
ATGTGGGCGAACTGGATCAAATGGCGTTGGCACCATGCCATGCCTTTTTCCAGTTCTACGTGGCTGATGGCAAACTTTCT
TGCCAACTGTACCAACGCTCTTGCGATGTGTTCCTTGGCTTGCCATTTAACATTGCCAGCTATGCGTTATTAGTTCACAT
GATGGCGCAGCAGTGTGATCTGGCCGTAGGCGATTTTGTCTGGACTGGCGGGGATACTCACTTGTATAGCAACCATATTG
ACCAGACGCATCTGCAATTGAGCCGTGAGCCACGAGCATTACCGAAACTGGTGATCAAACGTAAACCTGATTCATTGTTT
GACTACCATTTCGATGATTTTGATATTGAGGGCTACGATCCTCACCCTGGTATTAAAGCCCCTATCGCGATTTAA

Protein sequence :
MKQYLDLMKKVLEEGTPKADRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLNGDTNIAYLKENNVSIW
DEWADENGDLGPIYGKQWRAWGAADGRKIDQLSNVVNQLKQDPDSRRIIVSAWNVGELDQMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVGDFVWTGGDTHLYSNHIDQTHLQLSREPRALPKLVIKRKPDSLF
DYHFDDFDIEGYDPHPGIKAPIAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-86 63
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-56 45