Gene Information

Name : YpsIP31758_3819 (YpsIP31758_3819)
Accession : YP_001402773.1
Strain : Yersinia pseudotuberculosis IP 31758
Genome accession: NC_009708
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaV
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 4302636 - 4304684 bp
Length : 2049 bp
Strand : -
Note : with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system

DNA sequence :
ATGAGTAAGTCAGCACTGGTGCGGGGTTTGACGATGATCACCGCGCGGCAGGATATTTTTTTAGCGGTCATGTTGCTGGT
GGCGGTCTTTATGATGATCCTGCCACTGCCTACGACGATGGTGGATTTACTGATCGCCATCAATCTTGCCTTCTCCGTCA
TTCTCTTAATGATCTCGATCTATCTGCGCGATCCTTTGGAGTTCTCCGTCTTCCCGTCATTACTGTTGATCACCACCCTT
TATCGATTGGCACTAACGATCAGCACCACGCGACTGGTGCTGTTGCAACATGATGCCGGTGAGATTGTCGAGGCATTCGG
TCAGTTTGTCGTGGGCGGTAATCTGGCCGTCGGGATGATCATTTTTACCATTATCACGGTGGTCCAATTTATCGTGATTA
CCAAAGGTTCAGAGCGGGTTGCTGAGGTCAGTGCGCGCTTCTCACTTGATGGTATGCCGGGTAAGCAGATGAGCATCGAC
GGTGACATGCGTGCGGGTGCGATCGATTCGGTCGAAGCTAAACGGCTACGGGAGCGGGTACAAAAAGAGAGCCGCTTATT
TGGTGCTATGGACGGTGCCATGAAGTTTGTTAAAGGGGATGCCATCGCTGGGATCATTGTCATTCTGGTCAATATCATTG
GCGGTATCACTATTGGTGTGATGCAACACAAGATGTCCGCGGAAGAGGCGATGAATACCTACGCGGTATTATCGATAGGC
GATGGATTGTGCGCCCAAATCCCTTCATTACTGATCTCGATTACCGCCGGGATTATTGTTACCCGGGTTCCTGGCAGCAA
CAAACAGAGTCTGGCGAATGAGTTGGCGGTGCAGGTGGGGCGTCAACCGGATGCGCTGTGGTTAGCTGCCGCTATTCTGA
CGGTGTTCGCCCTGTTACCCGGCTTCCCGTTCCTGATCTTTATCACTTTGGCGGCCGCGGTTGCGGCTCCGGCTTTTTTA
CTTTATCGGAAGAACCGGCGGATATCGCAGGATGGTCGCGCAAATGGAGGCGGTGAAGAGGGGGCGGCCACGGGGCAGCG
TATGACGCCTGGTGCCGTACCGCTGATGCTGCACTGTGCATCAAATTTACATCACCCGCATTTAGGGCGCGATATTGATG
GCCTACGCTGGCGCTGGTTTGAGCATCTCGGTGTGCCATTGCCTGAGGTGGAGATCCGCTGTGATCCTACATTGGCAGAA
AATACCTTATCGGTGCAGGTGTATCAGGAGCGGGTGCTGGAGGTTGTGTTACCGCCCGACAGCTTGTTACTGACACGGCC
TTGCTCATCGTTAGTAACGAACAATCAGGTATTGGGCGCGAAGATGGGGTCATTTGATTGGCTGGATGCTAAACAGGCTA
TGCAAGCCAGAACCTTGGGTATCCCTTACGTGGAGGGGCATCAGCGGATCATCACCTGTCTGACCAGGGTGTTTGAACGG
TACACCGCCGAATTTATCGGCGTACAGGAGACTCGCTACCTGATGGATGCCATGGAAGGGCGCTATGGTGAGTTAGTGAA
AGAGCTACAACGGCAGATACCCGTCGGTAAAGTGGCTGAAATATTACAACGGCTGGTTGAGGAAAATATTTCCATTCGCG
ATTTACGGACTATTTTCGGCGCGTTGGTGGTTTGGGCACCGAAAGAAAAAGATATCGTGATGCTCACCGAATATGTCCGT
ATCGCCTTGCGCCGTCATTTGTGCCGTCGCTTTAGTCACAATAAAACCTGGATATCAGTATTACGCCTCGGTGATGGGGT
GGAGCATCTGATCCGCGACTCTATCCGCCAGACATCATCAGGCACTTACTCCGCACTGGAGGAGAGGCGATCCCTCTTGA
TCCTCAACAAAATAAAAAACGCATTTGCTGAAAACCAGGATGCGGTATTGCTTACCACCCTCGATGTTCGTCGCTTTGTC
CGCAAAATTATTGAGCGGGATCTCTTCGTGCTACCGGTACTTTCCTGGCAGGAACTGGGCGATGAAATGAATCTCAAGGT
GGCGGGCACCATTGAACTGATTGGCGATGAACTTGATGAAACTGCCTGA

Protein sequence :
MSKSALVRGLTMITARQDIFLAVMLLVAVFMMILPLPTTMVDLLIAINLAFSVILLMISIYLRDPLEFSVFPSLLLITTL
YRLALTISTTRLVLLQHDAGEIVEAFGQFVVGGNLAVGMIIFTIITVVQFIVITKGSERVAEVSARFSLDGMPGKQMSID
GDMRAGAIDSVEAKRLRERVQKESRLFGAMDGAMKFVKGDAIAGIIVILVNIIGGITIGVMQHKMSAEEAMNTYAVLSIG
DGLCAQIPSLLISITAGIIVTRVPGSNKQSLANELAVQVGRQPDALWLAAAILTVFALLPGFPFLIFITLAAAVAAPAFL
LYRKNRRISQDGRANGGGEEGAATGQRMTPGAVPLMLHCASNLHHPHLGRDIDGLRWRWFEHLGVPLPEVEIRCDPTLAE
NTLSVQVYQERVLEVVLPPDSLLLTRPCSSLVTNNQVLGAKMGSFDWLDAKQAMQARTLGIPYVEGHQRIITCLTRVFER
YTAEFIGVQETRYLMDAMEGRYGELVKELQRQIPVGKVAEILQRLVEENISIRDLRTIFGALVVWAPKEKDIVMLTEYVR
IALRRHLCRRFSHNKTWISVLRLGDGVEHLIRDSIRQTSSGTYSALEERRSLLILNKIKNAFAENQDAVLLTTLDVRRFV
RKIIERDLFVLPVLSWQELGDEMNLKVAGTIELIGDELDETA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 0.0 99
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 3e-158 58
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 1e-158 58
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 1e-158 58
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 1e-158 58
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 3e-158 58
escV CAC81861.1 EscV protein Virulence LEE II Protein 5e-125 50
escV AAK26714.1 EscV Virulence LEE Protein 4e-125 50
escV AAL57541.1 EscV Virulence LEE Protein 4e-125 50
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 6e-125 50
escV CAI43875.1 EscV protein Virulence LEE Protein 7e-125 49
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 4e-124 49
escV YP_003223476.1 translocator EscV Virulence LEE Protein 1e-124 49
escV AAC38382.1 EscV Virulence LEE Protein 4e-124 49
escV NP_290269.1 hypothetical protein Virulence LEE Protein 2e-123 49
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 2e-123 49
escV AAC31514.1 L0035 Virulence LEE Protein 1e-123 49
escV ACU09459.1 EscV protein Virulence LEE Protein 1e-123 49
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-120 49
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-120 49
unnamed AAL06368.1 EscV Virulence LEE Protein 1e-122 48
lssD AAO18050.1 LssD Virulence TTSS locus Protein 6e-121 46
invA AAS66860.1 InvA Not tested SSR-2 Protein 3e-85 42
hrcV AAT96193.1 HrcV Virulence T-PAI Protein 6e-89 41
hrcV AAT96139.1 HrcV Virulence T-PAI Protein 5e-89 41
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-91 41
hrcV AAR25631.1 type III secretion protein HrcV Not tested Not named Protein 8e-81 41
hrcV AAB05999.2 HrcV Virulence Hrp PAI Protein 2e-91 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG0514 Protein 6e-159 58
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG0729 Protein 2e-124 49
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG0813 Protein 8e-124 49
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG0064 Protein 5e-126 47
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG0198 Protein 3e-104 45
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG0384 Protein 4e-117 45
YpsIP31758_3819 YP_001402773.1 secretion system apparatus protein SsaV VFG2126 Protein 1e-94 42