Gene Information

Name : YpsIP31758_3818 (YpsIP31758_3818)
Accession : YP_001402772.1
Strain : Yersinia pseudotuberculosis IP 31758
Genome accession: NC_009708
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 4301312 - 4302649 bp
Length : 1338 bp
Strand : -
Note : identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546

DNA sequence :
ATGAAACTGCCTGATATCGCGCGGTTAACCCCCCGCCTGCAACAACAACTCACGCGACCGTCGGCACCACCGGAGGGCTT
GCGTTACCGTGGGCCGATTGTGGAGATTGGGCCGACCTTGTTACGAGCCAGCCTACCCAATGTGGCGCAGGGTGAATTAT
GCCGCATTGAACCGCAAGGGATGTTAGCTGAAGTGGTATCGATTGAGCAGGAAATGGCCTTGTTATCCCCCTTTGCCTCT
TCAGATGGCCTGCGTTGTGGGCAATGGGTGACGCCACTTGGACACATGCACCGGGTACAGGTGGGGGCTGATTTGGCCGG
GCGGATCTTGGATGGCCTAGGTGCTCCGATAGACGGCGGCCCCCCGCTGACGGGGCAGTGGCGTGAACTGGATTGCCCCC
CGCCTAGCCCATTAACCCGCCAGCCGGTAGAGCAAATGCTGACCACCGGGGTCCGCGCGATTGATGGGATATTGAGCTGT
GGCGAGGGCCAGCGTATTGGTATTTTTGCCGCCGCTGGCGTTGGGAAAAGTACTTTATTGAGCATGTTATGTGCTGATAG
TGCGGCCGATGTGATGGTGCTGGCACTGATTGGTGAGCGTGGGCGGGAGGTGCGCGAATTTCTTGAACAGGTGCTGACTC
CGGAGGCGCGTGCGCGCACCGTGGTGGTGGTGGCGACCTCTGACCGGCCAGCATTGGAGCGGTTGAAGGGGCTGTCTACT
GCCACCACGGTGGCGGAGTATTTTCGCGAACGTGGATTGAAGGTGTTGTTACTGGCGGATTCACTGACCCGCTATGCCCG
TGCCGCCCGTGAAATTGGTCTGGCGGCAGGCGAGCCACCGGCTGCTGGCAGTTTCCCCCCAAGTGTTTTTGCCAACTTAC
CCCGCCTGTTGGAGCGAACGGGTAACAGTGATCGCGGCAGCATTACGGCTTTTTATACCGTGCTGGTGGAGGGAGATGAC
ATGAATGAACCGGTGGCCGATGAAGTGCGTTCGCTGTTGGATGGGCACATCGTTTTATCACGACGGTTGGCCGGTGCCGG
GCATTATCCGGCGATTGATATTGCCGCCAGCGTCAGCCGTATCATGCCGCAAATCGTCAGTGCCGGGCAGTTGGCGATGG
CACAAAAACTACGGCGAATGCTGGCCTGTTATCAGGAGATCGAGCTGTTGGTGCAGATTGGTGAATATCAGGCAGGAGAA
GACCTACAGGCTGATGAAGCCTTACAACGCTATCCGGCAATATGCGCCTTTTTACAACAAGACCACAGCCTAACGCGTGA
CCCAGATACTGCTCATCTTGATACCACTCTGGAACACCTGGCGCAGGTTGTCGGTTGA

Protein sequence :
MKLPDIARLTPRLQQQLTRPSAPPEGLRYRGPIVEIGPTLLRASLPNVAQGELCRIEPQGMLAEVVSIEQEMALLSPFAS
SDGLRCGQWVTPLGHMHRVQVGADLAGRILDGLGAPIDGGPPLTGQWRELDCPPPSPLTRQPVEQMLTTGVRAIDGILSC
GEGQRIGIFAAAGVGKSTLLSMLCADSAADVMVLALIGERGREVREFLEQVLTPEARARTVVVVATSDRPALERLKGLST
ATTVAEYFRERGLKVLLLADSLTRYARAAREIGLAAGEPPAAGSFPPSVFANLPRLLERTGNSDRGSITAFYTVLVEGDD
MNEPVADEVRSLLDGHIVLSRRLAGAGHYPAIDIAASVSRIMPQIVSAGQLAMAQKLRRMLACYQEIELLVQIGEYQAGE
DLQADEALQRYPAICAFLQQDHSLTRDPDTAHLDTTLEHLAQVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 0.0 99
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-112 59
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-111 59
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-112 59
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-111 59
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-112 59
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-99 56
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-95 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-95 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-94 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-94 52
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-98 52
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-98 52
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-99 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-95 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-96 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-96 51
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-95 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-96 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-101 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-101 51
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-102 51
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-75 50
escN AAL57542.1 EscN Virulence LEE Protein 5e-101 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-101 50
escN AAK26715.1 EscN Virulence LEE Protein 5e-101 50
escN AAC38383.1 EscN Virulence LEE Protein 3e-101 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 6e-101 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-101 50
escN AAC31513.1 L0034 Virulence LEE Protein 4e-101 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-101 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-101 50
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-83 49
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-75 48
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-75 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-76 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-76 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-78 48
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-79 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 8e-80 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-77 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-76 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 9e-79 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-70 47
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-71 45
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-71 45
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-71 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 4e-71 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-68 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-68 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0515 Protein 6e-112 59
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0192 Protein 4e-99 58
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0390 Protein 9e-98 56
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG2331 Protein 3e-76 54
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0048 Protein 1e-96 53
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0730 Protein 2e-101 50
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0812 Protein 2e-101 50
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG2144 Protein 3e-84 50
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG1254 Protein 7e-84 50
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG2499 Protein 6e-77 50
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG1778 Protein 4e-70 47
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG2459 Protein 8e-75 45
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG0555 Protein 2e-71 45
YpsIP31758_3818 YP_001402772.1 type III secretion system ATPase VFG1008 Protein 1e-68 44