Gene Information

Name : fliI (YpsIP31758_2293)
Accession : YP_001401262.1
Strain : Yersinia pseudotuberculosis IP 31758
Genome accession: NC_009708
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2599034 - 2600452 bp
Length : 1419 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGACCCCCCGCCTCAGCCGCTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCAGCCAAACGACAACAATCCGCCG
TTATGGCCGCTTGACCCGCGCCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTGCCGTTAGGGGCGACCTGTCTGA
TTGAGCGCCATAATGGCGGTGAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAACGGTCAGCATCTGTTTCTTATG
CCTTTGGAAGATGTGGAAGGTATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCACCAGCGGCACGTCTGCCAGTAA
ACAGTCAATTTCTAGTAAACAATCAATTCCCAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAGTTAT
TGGGCCGGGTATTGGATGGCAGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACTGATT
ACACCACCGATAAACCCTTTGCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCTTGTT
GACGGTCGGGCGCGGCCAGCGGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATGGCCC
GTTACACACAGGCTGACGTGATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAATATT
CTCGGGGCTGAAGGCCGTGCCCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAGGTGC
CGCCTATGCCACCCGTATTGCCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACCCGCT
ATGCCATGGCGCAACGTGAAATCGCGCTGGCTATCGGCGAACCTCCCGCGACCAAAGGCTATCCGCCCTCCGTATTCGCC
AAATTACCGGCACTGGTTGAACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACTGCATTTTATACCGTCCTCAC
CGAAGGTGATGATCAACAAGACCCTATTGCTGACTCCGCGCGCGCCATCCTTGATGGGCATGTGGTGCTATCTCGCCGTT
TAGCTGAATCCGGTCACTATCCAGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACTTCATTAATCGATGATGAC
CATTACAGCCGGGTGCGCCAATTTAAACAACTGCTTGCCAGCTATCAGCGTAACCGAGATTTAGTCAGTGTGGGGGCTTA
CGCTGCGGGCAGTGATCCATTATTGGACAAGGCGATTGCCCTGTATCCGCAGATGGAAATTTTCTTGCAGCAAGGCATGT
TTGAGCGCAGCAGTTTTGACGATGCCTGCCAGCATTTGAAGAGTTTATTTCCAGGATAA

Protein sequence :
MTPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLM
PLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLI
TPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGREVKDFIENI
LGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFA
KLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDD
HYSRVRQFKQLLASYQRNRDLVSVGAYAAGSDPLLDKAIALYPQMEIFLQQGMFERSSFDDACQHLKSLFPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-70 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-67 49
escN AAL57542.1 EscN Virulence LEE Protein 1e-68 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 9e-69 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-68 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-68 48
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-68 48
escN AAK26715.1 EscN Virulence LEE Protein 1e-68 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-65 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-66 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-66 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-68 47
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-67 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-68 47
escN AAC38383.1 EscN Virulence LEE Protein 6e-68 47
escN AAC31513.1 L0034 Virulence LEE Protein 3e-68 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-68 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-68 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-71 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-71 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 9e-61 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 9e-61 46
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-76 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-77 45
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-76 45
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-76 45
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-76 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-75 45
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-76 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-72 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-72 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-57 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-57 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-57 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-57 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-57 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-56 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 4e-71 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_001401262.1 flagellum-specific ATP synthase VFG2331 Protein 0.0 93
fliI YP_001401262.1 flagellum-specific ATP synthase VFG2499 Protein 6e-143 67
fliI YP_001401262.1 flagellum-specific ATP synthase VFG1254 Protein 2e-118 59
fliI YP_001401262.1 flagellum-specific ATP synthase VFG0048 Protein 4e-75 51
fliI YP_001401262.1 flagellum-specific ATP synthase VFG0192 Protein 1e-77 50
fliI YP_001401262.1 flagellum-specific ATP synthase VFG0730 Protein 3e-68 47
fliI YP_001401262.1 flagellum-specific ATP synthase VFG0812 Protein 2e-68 47
fliI YP_001401262.1 flagellum-specific ATP synthase VFG2459 Protein 1e-57 45
fliI YP_001401262.1 flagellum-specific ATP synthase VFG0555 Protein 6e-58 43
fliI YP_001401262.1 flagellum-specific ATP synthase VFG0390 Protein 1e-72 42
fliI YP_001401262.1 flagellum-specific ATP synthase VFG2144 Protein 1e-79 42
fliI YP_001401262.1 flagellum-specific ATP synthase VFG1778 Protein 2e-55 42