Gene Information

Name : lysS (JJD26997_1556)
Accession : YP_001398557.1
Strain : Campylobacter jejuni 269.97
Genome accession: NC_009707
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1375940 - 1377445 bp
Length : 1506 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTGATAATATTTTAGAACAACAAAGAATAGAAAAAGCTAAAGAGTTAAAAAATTTAGGAATCAATCCTTATCCTCA
TTTTTTAGAAAAGGAAATGTCTTTAAAGACTTTTAAGGATAAATTTTCTTATATTTTAGAGCAAGTTGAAAAAAGAGATG
AAAGTGTCAATGCTGTTGTTGCAGGACGTTTGAAACTTTTGCGTATAGCTGGGAAATCGATTTTTGCAAACATTGAAGAT
GAGGATACAAATTTACAAATTTATTTTAGTAAAGATAGCGTAGGCGAAGAACTTTATACGATTTTAAAAAAGAATTTAGA
GGCGGGTGATATTGTTTTGGTTAAAGGTTTTCCTTTTGTAACTAAAACAGGTGAGTTTAGTTTGCATGCAAGCGAAGTAA
AACTTGCTACAAAAGCTATTGTTCCTTTACCTGAAAAATATCATGGATTAACAGATATTGAGCAAAGATATCGCAAACGT
TATGTTGATATGATAATGAATGCCGAAGTTAGAAAAGATTTTTTAGTGCGTTCTAAAGTGGTGAGTTTAATCCGTCATTT
TTTTGAAAATAAAGGCTTTTTAGAAGTAGAAACTCCTATGATGCATCCGATTGCAGGTGGAGCAAACGCTAAACCTTTTG
TAACTTTTCATAATTCTTTAGGTGTAGAAAGATTTTTAAGAATTGCTCCAGAACTTTATCTTAAAAGACTTGTAGTGGGT
GGTTTTGAGGCAGTTTTTGAAATCAATCGTTGTTTTAGAAATGAAGGTATGGATTTAACTCATAATCCCGAATTTACAAC
TATAGAATTTTATTGGGCTTATCATAATTATAAAGATTTAATGGATTTAACTGAAGAACTTTTTGCTTTACTTTTGGATA
AACTTAATCTAGGAAAAACAATAGAATTTGATGGAAAAATGATAGATTTTTCTAAACCTTTTGAAAGAATAACCTATAAA
GACGCACTTTGTAAATATGGTGGTTTAGATAGGGATTTAATCGAAGATAAAGAAAAAATTCTTGCCAAATTAAAAACAGA
CGGTTTTGAAGCGAACGAAAAGCTTGAACTTGGACATTTGCAAGCTGAACTTTTTGATAATTACGTGGAAGAAAAATTGA
TCAATCCTACTTTTGTGAGTGATTTTCCTATTTCTATAAGTCCTTTATCAAGACGTAGCGATGAGAATTCTCAGATTGCT
GAAAGGTTTGAGCTGTTTATTTGCGGAAGAGAATTGGCAAATGGTTTTAATGAGCTTAATGATCCGCTTGATCAATATGA
GAGATTTTTAAAACAAATTGAAGCTAAAAATGCAGGCGATGAAGAGGCTTGTGAAATGGATGAAGATTTTGTAAATGCTT
TGGGTTATGGAATGCCTCCAACGGCAGGGCAGGGCATAGGCATAGATAGACTTGTTATGCTTTTGACAAATAAAAAATCT
ATTCGAGATGTGATATTGTTTCCTGCAATGCGTCCATTAAAATCAGAACTAAAGGAGAAAGAATGA

Protein sequence :
MFDNILEQQRIEKAKELKNLGINPYPHFLEKEMSLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIED
EDTNLQIYFSKDSVGEELYTILKKNLEAGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKR
YVDMIMNAEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLVVG
GFEAVFEINRCFRNEGMDLTHNPEFTTIEFYWAYHNYKDLMDLTEELFALLLDKLNLGKTIEFDGKMIDFSKPFERITYK
DALCKYGGLDRDLIEDKEKILAKLKTDGFEANEKLELGHLQAELFDNYVEEKLINPTFVSDFPISISPLSRRSDENSQIA
ERFELFICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQGIGIDRLVMLLTNKKS
IRDVILFPAMRPLKSELKEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-105 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001398557.1 lysyl-tRNA synthetase VFG1668 Protein 5e-106 48