Gene Information

Name : polA (CKL_0669)
Accession : YP_001394071.1
Strain : Clostridium kluyveri DSM 555
Genome accession: NC_009706
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 659557 - 662199 bp
Length : 2643 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGTCTCGAGAAAAATTATTGATATTGGATGGACATAGTTTAATGAATAGAGCTTTTTATGCACTGCCGGATTTGACCAA
TTCAGAAGGGACTCATACAAATGCAGTTTATGGATTTATAAATATGCTGTTGAAAATGAAAAAGGAAATTGAACCCAGTC
ACATAGTATGTACTTTTGATAGAAGTGCACCTACCTTTAGACATGATAAATATAGTGAATATAAAGCCGGCAGAAAAAGA
ATGCCTCCTGAGCTGTCAGAACAGTTTCCTATAGTTAAGGAAATATTGGAGCTTTTATCCATAAATATTTTTGAAATAGA
TGGATTTGAAGCAGATGATCTTATGGGTACATTATCCGTTTTTGCAGAAAAAAAAGGCATGGAAGTATATATAGTTACAG
GAGATAGAGATGCCCTCCAGCTGGCCACAGATTCAGTGAAAATTGTAATAACTAAAAAAGGTATAACACAAAAGGAAATA
TATGATAGAAATAAAATTATAGATGATTATGGAGTAACCCCTACGGAATTTATAGATGTAAAAGGGCTTATGGGGGACGC
TTCGGATAATATTCCTGGGGTACCTGGTATAGGAGAGAAAACTGCCCTTAAATTGATAAAAGAGTATAAAAGCATAGAAA
ATGTACTTTGTAATATAGATAATATTAAAGGGAAAAAAGTTCAAGAAAATTTAAAAAATTATATGGAACAGGCTGTATTT
AGTAAAAAGCTTGCCACTATTGTCACAGATGTTCCTATAGAACTGGATTTACAATCTATTGAATCGAAAGAACAATATAA
TGCCGAAGGCTTAAGAAAATTATTTGAAAAACTTCAGTTTAAATCCTTAATGGATAAAATACCTAAAGTGGAGGAACAGG
ATAAAATAGAAGTGGAAGATTTTCAGGTAGAATGTGAGGTTATAGATACTTTAAATAAAGTTCATAACTTTATAGACTCT
TTAGAAGCTGAAGATATGAAAAATAAATTACTTTATATTAATTTCAAAGTTGTAGATGAGAATAGTTATGCTAAAAATTA
CATAGATAAGATATTTATAAATATAGGAGAAAAAAATTTTGAAATACACATAAAAGAAATATATGATGAAAATAAAATTA
AAGCAGTGGAAACAGCTAAAATGTTGTTTGAAAATTCTAGCTTAAGTAAAGTGAGTTATGATGTGAAAGTACCTTGCAGT
ATATTGCATAGAATGGGAATAAAGCTTTTAGGCATAGAATTCGATATAAAGATAGCAGCTTATTTAATGGATCCGGCTAG
GACCAACTATGAATTACCGGATATTATTAAGGAGTATCTGAATATAGAAATCTCTGAGGAAAGGGAAGATTGTTTTATAA
AAGAAACATTGTTGTTTAGCAGGTTATACTCTACTTTAAAGAAGAAGATATCAGATTCTTCTATGGATAAATTGTTGTAT
GAAGTAGAACAGCCACTTACTTTTGTACTGGCATCTATGGAGTGTGAAGGATTTAAGGTGGATAAGGATAAGTTAACTGA
GATGGAGGAGAAATTTAAAATAGAAATAGATAAGGTACAAAAGGAAATATATTTTCTCTCCGAGGAAGAATTTAATATAA
ATTCTCCAAAACAGCTGGGTAAAATATTATTTGAAAAGTTGGATCTGCCTGTCATAAAAAAGACTAAAACGGGATATTCC
ACTAATGCAGATGTATTGGAAAGATTACATGGTAAACATCCTGTAATTGAAAAAATAATCTATTATAGACAGCTTACTAA
ATTATATTCCACATATATTGAAGGATTAAAAGGAGTAATAGAGGAAGATGGTAAGATTCATTCTAATTTTAATCAAACAG
TAACTACTACAGGGAGACTTTCAAGTACCGAACCCAATCTTCAAAATATACCTATAAAATATGAGATGGGAAAAGAAATA
AGAAAAATATTCATACCAGATAATAGGGATTGTGTTATACTCTCGGCAGATTACTCGCAAATAGAACTTAGGGTGCTTGC
CCATATATCAGGGGATGAAAATTTAATAAATGCATTTATAAACCACAATGATATTCACACTAAAACTGCATCAGAGGTAT
TTAATGTACCTTTGGGAGAAGTAACATCTACACAGAGAAGTAATGCAAAAGCCGTAAATTTTGGTATAGTATATGGTATT
GGTGATTTTAGCTTAGCAAGGAATTTAAATATACCCAGAAAAGAAGCAAAATCTTATATAGATGCTTATTTTGAAAAATA
TCCTAAAGTGAAGTTGTACATGAATGATATAGTAAAGCAGGCCGAAAAGAATTTTTATGTTACCACCATTTTAAATAGGA
GAAGGTTTATACCGGAGATAAAATCTTCTAATAAAATAATAAAAGCTCTAGGAGAAAGGTTTGCCATGAATACTCCCATT
CAAGGAAGTGCAGCGGATATTATAAAAATAGCTATGGTAAATGTTTTTAATAGATTAAAAGATAATAATTTTAAAAGCAA
GATAATACTTCAGGTTCACGATGAACTGGTATTAAATGTGTATAAAGATGAACTAAAAGATGTAAAAGACATTGTAAAAG
AGGAAATGGAAAATGTGTTTAAGCTAAAGGTTCCTCTTGAAGTGGATATAAGTATAGGGGATAATTGGTATCAAGTTAAA
TAA

Protein sequence :
MSREKLLILDGHSLMNRAFYALPDLTNSEGTHTNAVYGFINMLLKMKKEIEPSHIVCTFDRSAPTFRHDKYSEYKAGRKR
MPPELSEQFPIVKEILELLSINIFEIDGFEADDLMGTLSVFAEKKGMEVYIVTGDRDALQLATDSVKIVITKKGITQKEI
YDRNKIIDDYGVTPTEFIDVKGLMGDASDNIPGVPGIGEKTALKLIKEYKSIENVLCNIDNIKGKKVQENLKNYMEQAVF
SKKLATIVTDVPIELDLQSIESKEQYNAEGLRKLFEKLQFKSLMDKIPKVEEQDKIEVEDFQVECEVIDTLNKVHNFIDS
LEAEDMKNKLLYINFKVVDENSYAKNYIDKIFINIGEKNFEIHIKEIYDENKIKAVETAKMLFENSSLSKVSYDVKVPCS
ILHRMGIKLLGIEFDIKIAAYLMDPARTNYELPDIIKEYLNIEISEEREDCFIKETLLFSRLYSTLKKKISDSSMDKLLY
EVEQPLTFVLASMECEGFKVDKDKLTEMEEKFKIEIDKVQKEIYFLSEEEFNINSPKQLGKILFEKLDLPVIKKTKTGYS
TNADVLERLHGKHPVIEKIIYYRQLTKLYSTYIEGLKGVIEEDGKIHSNFNQTVTTTGRLSSTEPNLQNIPIKYEMGKEI
RKIFIPDNRDCVILSADYSQIELRVLAHISGDENLINAFINHNDIHTKTASEVFNVPLGEVTSTQRSNAKAVNFGIVYGI
GDFSLARNLNIPRKEAKSYIDAYFEKYPKVKLYMNDIVKQAEKNFYVTTILNRRRFIPEIKSSNKIIKALGERFAMNTPI
QGSAADIIKIAMVNVFNRLKDNNFKSKIILQVHDELVLNVYKDELKDVKDIVKEEMENVFKLKVPLEVDISIGDNWYQVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 2e-168 44