Gene Information

Name : pyk (CKL_3558)
Accession : YP_001396920.1
Strain : Clostridium kluyveri DSM 555
Genome accession: NC_009706
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3602958 - 3604715 bp
Length : 1758 bp
Strand : -
Note : pyruvate kinase

DNA sequence :
ATGCAAAAAACTAAAATGATTTTTACAATTGGACCCACAAGTGATTCAGAAGAAGTTTTGTCAAAACTTATTGAAGCTGG
CATGAATGTAACTAGACATAATTTTTCTCATGGAGACTATCCAAGTCATGAAAAGAGAATAAATACAGTGAAGAAACTCA
GAGAAAAGTACAGTAAACCTATAGCAATTATGCTGGATACTAAAGGGCCTGAAATAAGAACGGGAAATTTTGAAAATGAT
AAAGCTCAGTTAAAAGAGGGAGATAAATTTACTATCTACTGTAGAGATAATATCATAGGGGATAATACTAGATGCTCCAT
AACCTATGACGGGTTAAGCAGTGACTTGAAAAAAGGAGACAGTATATTAATTGATGATGGATTAGTTGCTTTGGAAGTGG
ATGATATTGAAAATAATAAAATATACTGCATAGTTAAAAATAATGGAACAATCAGTAATCATAAAGGGGTAAATGTACCA
GGAGTTTCTACTTCGCTGCCAGCATTAACAGAAAAGGATAAAGGGGATTTGATATTTGGATGCAAGATTGGCGTAGATAT
GGTAGCTGCTTCTTTTATAAGAAAAGCTGCTGATATACTTACCATAAGAAAGGTACTGGAGGCAAATGGAGGACAAGATA
TACAGATATTCTCTAAGATTGAAAATCAAGAAGGGGTTGACAATATAGATGAAATAATAAAGTTTTCTGATGGAATAATG
GTGGCAAGAGGAGATATGGGAGTGGAAATTCTCATAGAACAAGTACCTTTAATACAAAAAACTATAATACAAAAGTGTAA
TAAAGCAGGTAAACCTGTTATAACTGCAACTCAGATGCTTGATTCTATGATAAGGAATCCAAGACCTACCAGGGCTGAAG
CATCAGATATAGCCAATGCCATATTTGATGGAACAGATGCCATAATGTTAAGTGGTGAAACTGCCAATGGAAAATATCCT
GTAGAAGCAGCACGGACTATGTCAAGAATAGCCCAGGCAGCAGAAGAAAAAATCGACTACGATTCCTTATTAAAAAAAAG
AAGGGAAGTTCATATACAAAATGTACCAAATGCCATAAGTCTTGCTACCTGCAGCACTGCTTCAGAATTAAAAGCTTCTG
CTATAATAACTGCTACACAGAGTGGACACACAGCTAGAATGGTTTCAAAGTATAGACCACAATGTCATATTATAGCTGTA
ACTCCAAGTGGTAAAGTGGCAAGAAGGCTTGCATTAAATTGGGGGGTATTTCCCATACTTACTAAAAGGGTGGATTCTAC
GGATGAATTAATAGAAGATTCAGTTAAGATAGCATTAAAAAGTGGCTATGTTAAAAAAGGAGATCTGGTAATTATAGCAG
CAGGCATACCGGTTAGTTATTCTGGCACTACTAATATGTTAAAGGTTCATATAGTTGGAGATATATTAGTTCAGGGGAGA
GGGGCAGGAGTTAGACCCGGTTATGGAAATGCAAAAATAGTTTATAATCCTAAGGATGCCCGGGAGATAATAGAAGATGG
GGATATTTTAGTAGTTAAAGATCTAGATATAGAATATATGGATGTATTGGATAGAGTTTCAGGAATTGTAGCGGAAAATG
GAGGATTAACATCCCATCTTGCTATTGAATGCCTTACAAGGGAAATACCTATTATCTGTGGAGCTGGAGGAGCCACTGAA
ATATTGAAAACAGGTACATTTATAACTATGGATATTATAAGAGGAATAGTGTATAATGGCAGAGCCAATATAATGTAA

Protein sequence :
MQKTKMIFTIGPTSDSEEVLSKLIEAGMNVTRHNFSHGDYPSHEKRINTVKKLREKYSKPIAIMLDTKGPEIRTGNFEND
KAQLKEGDKFTIYCRDNIIGDNTRCSITYDGLSSDLKKGDSILIDDGLVALEVDDIENNKIYCIVKNNGTISNHKGVNVP
GVSTSLPALTEKDKGDLIFGCKIGVDMVAASFIRKAADILTIRKVLEANGGQDIQIFSKIENQEGVDNIDEIIKFSDGIM
VARGDMGVEILIEQVPLIQKTIIQKCNKAGKPVITATQMLDSMIRNPRPTRAEASDIANAIFDGTDAIMLSGETANGKYP
VEAARTMSRIAQAAEEKIDYDSLLKKRREVHIQNVPNAISLATCSTASELKASAIITATQSGHTARMVSKYRPQCHIIAV
TPSGKVARRLALNWGVFPILTKRVDSTDELIEDSVKIALKSGYVKKGDLVIIAAGIPVSYSGTTNMLKVHIVGDILVQGR
GAGVRPGYGNAKIVYNPKDAREIIEDGDILVVKDLDIEYMDVLDRVSGIVAENGGLTSHLAIECLTREIPIICGAGGATE
ILKTGTFITMDIIRGIVYNGRANIM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-110 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-110 53
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-111 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-109 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_001396920.1 hypothetical protein VFG0479 Protein 1e-110 53