Gene Information

Name : smpB (CKL_3375)
Accession : YP_001396749.1
Strain : Clostridium kluyveri DSM 555
Genome accession: NC_009706
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3424634 - 3425107 bp
Length : 474 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGTCGGCTAAAAATAAATCCAATAATAAAACTCTTGCGGAAAATAGAAAGGCAAGACATGATTATTTCATTGAAGAATC
AATGGAAGCGGGAATACAATTGGTTGGAACCGAGGTTAAATCTATAAGGGCGGGAAAATCCAATTTAAAAGATAGCTATG
GTGAAATAATAAATGGAGAAATTTTTATACGTAATATGCATATAAGTCCCTATGAAAAAGGAAATATATTTAATAGAGAT
CCTCTAAGGGACAGAAAGTTACTTCTCCATAAGAAGGAAATAGCAAGACTGCTTGGATATACTGCACAGCAGGGATATAC
TATTGTGCCATTATCTCTTTATCTTAAAAATGGCAGGGTGAAAGTAAATCTAGCAGTAGCCAAAGGAAAGAAAAACTATG
ATAAAAGGGATTCCATGCTGGAGAAAGCTGCTAAAAGAGATATAGAGAGACAAATGAAAGAGAGATTTAGGTAG

Protein sequence :
MSAKNKSNNKTLAENRKARHDYFIEESMEAGIQLVGTEVKSIRAGKSNLKDSYGEIINGEIFIRNMHISPYEKGNIFNRD
PLRDRKLLLHKKEIARLLGYTAQQGYTIVPLSLYLKNGRVKVNLAVAKGKKNYDKRDSMLEKAAKRDIERQMKERFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-43 65
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-28 45
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-31 45