Gene Information

Name : metB1 (CKL_1002)
Accession : YP_001394392.1
Strain : Clostridium kluyveri DSM 555
Genome accession: NC_009706
Putative virulence/resistance : Resistance
Product : protein MetB1
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1014831 - 1015979 bp
Length : 1149 bp
Strand : +
Note : cystathione gamma-synthase

DNA sequence :
ATGAAAATTGAGTCATTGTTGATACATGGTGGAATAGATGGAGATAAAATTACGGGAGCAGTTAGTGTGCCTATATATCA
AACTTCTACTTACAAGCAGGAGGCACTTGGTAAAAATAGCGGTTATGAATACTCTAGGACAGGAAATCCCACAAGAGAAG
CTGTGGAAAAATTAATTGCAGATTTAGAAGAAGGATGCAGAGGGTTTGCCTTTGCATCAGGACTTGCGGCTATATCAGCA
GTGCTTATGCTCTTTAAAAGTGGAGATAAGGTAATACTTTCTAGTAATGTATATGGAGGAACCTTTAGAGTTGTAGATAA
GATATTTAAAAATTTTAATTTAGAGTATGAATTAGTAGATACCAGTGACCTGGAAAAAGTTAGAGAGAGTCTTAATCGAA
ATCAAAATGTTAAAGCAATATTCATTGAAACTCCTACTAATCCTCTTATGACTATAACGGATATAGCAAAGATAAGTGAA
ATTGCCAGAGAAAATAAAGTGATGACAATTGTAGATAATACCTTTATGACTCCATATCTGCAAAAACCTATAAAATTGGG
AGCTGATATAGTACTCCATAGTGCTACTAAATATTTGGGGGGACACAGTGATTTGATTGCTGGTCTCCTTGTAGTAAACA
ATGAAGAATTAGGAGAGAAAATTCATTTTATTCAAAATTCTACAGGAGGTATATTAAATCCATTTGACAGTTGGCTTCTA
ATAAGGGGAATAAAAACATTGTCTGTTAGGATGGACAGACACGATGAAAATGCTAATTATACAGCTGAATTTTTAAAGGG
AAATAATTTAATAGATAAAATTTATTACCCAGGATTTTTAAACCATCCTGATCATGAAATTCAAAAATCTCAGGCCAGAG
GATATGGAGCAATTATCTCTTTTGTATTAAAAGATGAATTAGATATAAATAAATTTTTTAAAGGATTAAAACTTATAACT
CTAGGAGAAAGTCTGGGAGGAGTAGAATCCCTGGTATGCCATCCAGCTACTATGACCCATGCAGCTATACCTTATGAGAT
AAGACAGGAGATTGGAATAGAAGATGGGTTAATTAGATTGTCTGTAGGTCTTGAAAATAAAGAAGATCTCATAGAAGATT
TAAAAAATGCATTGGAGTTTGCAAGATGA

Protein sequence :
MKIESLLIHGGIDGDKITGAVSVPIYQTSTYKQEALGKNSGYEYSRTGNPTREAVEKLIADLEEGCRGFAFASGLAAISA
VLMLFKSGDKVILSSNVYGGTFRVVDKIFKNFNLEYELVDTSDLEKVRESLNRNQNVKAIFIETPTNPLMTITDIAKISE
IARENKVMTIVDNTFMTPYLQKPIKLGADIVLHSATKYLGGHSDLIAGLLVVNNEELGEKIHFIQNSTGGILNPFDSWLL
IRGIKTLSVRMDRHDENANYTAEFLKGNNLIDKIYYPGFLNHPDHEIQKSQARGYGAIISFVLKDELDINKFFKGLKLIT
LGESLGGVESLVCHPATMTHAAIPYEIRQEIGIEDGLIRLSVGLENKEDLIEDLKNALEFAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-94 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-95 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-68 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB1 YP_001394392.1 protein MetB1 BAC0207 Protein 3e-63 41