Gene Information

Name : hemC (CLI_1007)
Accession : YP_001390273.1
Strain : Clostridium botulinum Langeland
Genome accession: NC_009699
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1054356 - 1055228 bp
Length : 873 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAATTTTATAATAGCCACAAGAAGAAGTAAGCTTGCTCAGGTGCAAACAGAAATAATAATAGATTTATTAAATAAAAA
ACATGATATAGAATGTGAAAAATTATTAATAGAAACTGTAGGAGATAAAATATTAGAAGTATCCTTAGATAAAATAGGTG
GAAAAGGACTATTCGTTAAAGACATAGAAGTAGCTATGCTGGAGCAAAGGGCAGATGCAGCAGTGCATAGTATGAAGGAT
GTGCCCTATGAAATGCCAAAAGGTTTTGAGATAATAGCTATTCCAAAGCGAGAAGATGTAAGAGATGCCTTTATATCCTT
AGACAATATAAAATTTAAGGATTTAAGAAAGGGAGCTAAAATTGGTACAAGTAGTAGGAGAAGGGCAGCCCAATTAAAGC
TTCTACGCCCAGATTTAGATATTGTTCCTATAAGAGGAAATGTTCAAACTAGGATAGAGAAAATAAAAAAAGAAAATCTA
GATGGAATAATATTAGCAGTAGCAGGCCTTAAAAGGGTAAATTTAGAACATCTAATTACAGATTATTTTGATACAAAAGA
AATGGTACCCGCAATTGGACAAGGTGCCTTAGGTATAGAAGTTATGGAGGAGCATCCTAAAAAGGAGTTATTTAAAGATT
TAGATCATTATAATTCAAAAATATGTGTTTTGGCAGAAAGAGCTTTTATGAGGGAACTAGATGGAGATTGCCATTCAACT
ATAGGAGCCTATGCATCTATAAAAGATAATATAATGCATATAATAGGCATATTTGAAAGAAAAAATAAAATTATTAAAAA
AGAAATTACAGGAACAAAAGATCAGTATGAAAAACTAGGCATAGCCTTAGCAGAGCATATACTGAAGGACTAA

Protein sequence :
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKD
VPYEMPKGFEIIAIPKREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENL
DGIILAVAGLKRVNLEHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-48 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-48 42