Gene Information

Name : thiC (CLI_2967)
Accession : YP_001392192.1
Strain : Clostridium botulinum Langeland
Genome accession: NC_009699
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3142127 - 3143440 bp
Length : 1314 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATTATACAACTCAAATGGATGCTGCTAAAAAAGGAATAGTTACAAAAGAGATGGAAATAGTAGCTAAAAAGGAAAA
TATGAATGTGAAAGACCTTATGGAATTGGTATCTAAAGGTAAGGTTGCTATACCTGCTAATAAAAATCATAAATCTTTAG
ATCCAGAAGGAATAGGACAAGGTTTAAGAACTAAAATAAATGTCAATTTAGGAATATCTAAAGATTGCTATAATATAGAT
ATGGAATTAGAAAAAGTACAAAAAGCAATAGATATGAAGGCAGAAGCTATAATGGATTTGAGCTGCTTTGGAAAAACAGA
AGAATTTAGAAAAAGATTGATAGACATGTCACCAGCCATAATAGGTACTGTTCCTATATATGATGCAGTAGGTTTCTATG
ATAAAGAATTAAAAGATATTACATCAGAAGAATTTTTAAAGGTAGCAGAGAAGCATGCAGAGAATGGAGCAGACTTTTTA
ACAATACATGTAGGTATGAATAGAAAAACTGCAGCTACATTTAAGAAAAATCCAAGAAGAATGAACATAGTTTCAAGAGG
AGGATCCCTTTTATATGCATGGATGGAACTAAATAATAAAGAAAATCCATTCTATGAAGGATTTAATAAACTTTTAGATA
TATGTGAAAAGTATGATGTTACATTAAGCTTAGGAGATGCTTGTCGTCCAGGCTGTATAGAGGATTCTACAGATGCAAGC
CAGATAGAAGAACTTATAGCTTTAGGGGAACTTACTAAAAGAGCCTGGGAGAGGAATGTACAAGTTATAATAGAGGGACC
AGGACACATGACTTTAGATGAAATAGAAACAAATATGAAAATAGAGAAAAAATTATGTCATGGAGCTCCGTTCTATGTTT
TAGGACCAATAGTTACAGATATAGCTCCAGGTTATGATCACATAACTTCAGCTATAGGTGGTGCTATTGCAGCAACTCAT
GGTGCAGATTTCTTATGCTATGTAACTCCAGCAGAGCATTTAAGATTACCAAACTTAGATGATATGAAGGAAGGTATAAT
AGCGACAAAGATAGCAGCTCATGCAGCAGATCTAGCTAAAGGAGTAAAGGGAGCAAGAGATTGGGATAATGCTATGGCTA
AAGCTAGAAGAGATTTAGACTGGGAAAGAATGTTTGAGTTATCTATAGATGAAGAAAAAGCTAGAAGATATAGAGAAGAA
TCTAAGGCAAAAAGTAAAGATTCTTGTACAATGTGCGGAAAAATGTGTGCAGTAAGAAATATGAACAGAGTTACAGAAGG
AAAAGACTTAAACATGTTAAGAGATGATGATTAA

Protein sequence :
MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNID
MELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFL
TIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFNKLLDICEKYDVTLSLGDACRPGCIEDSTDAS
QIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATH
GADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREE
SKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-68 44
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-68 44
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 5e-66 42