Gene Information

Name : polA-1 (CLI_2434)
Accession : YP_001391676.1
Strain : Clostridium botulinum Langeland
Genome accession: NC_009699
Putative virulence/resistance : Unknown
Product : DNA-directed DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2561611 - 2563587 bp
Length : 1977 bp
Strand : -
Note : identified by similarity to SP:P06225; match to protein family HMM PF00476

DNA sequence :
ATGGTGATATTTATTGATACTTTATCTATAGATGTTGAAACATATAGCAGTATGGATATAAAGACTTCAGGTGCTTATAA
ATATTGTGAATCTCCTGATTTTGAAATATTACTATTTGCTTATGCTTTTAATGATGAACCAGTACAAATAGTAGATTTAG
CAAATGGAGAAAAATTACCTTCAAATGTATTTTATGCCTTAACAGATCCAAACATTATAAAAACTGCATTTAATGCTAAC
TTTGAAAGAAATTCAATAAAGAATCAATACCCAGCTTTATGCCCACCAGAACAATGGGAATGTACCATGGTAAAAGCTTT
GACACTAGGGCTACCAAGTTCCTTGGATATGGTTGGTAAGGCTTTAAAGTTTGAAGAGGATAAGCAAAAGATGAAAGAAG
GTAAGGCTTTAATACAATATTTTTGTAAGCCTTGTAAACCTACTAAAACCAATGGTAAGAGAACTAGGAATCTTCCAGAA
CATGATATGGAGAAATGGGAAACTTTTAAAGAATACTGTAAGCGAGATGTTGAAGTAGAAAGAGAAATAAGAAATTTATT
AAATAGATATGAAACTAAAGTAGAAGAACAAAAATTATGGCAGCTGGACCAACACATAAATGATAGAGGTATTGGTACTG
ATTTAATACTTATAAAGCAGGCTATTGAATGTGATACAAACTATACTGAAAGATTAACAAAGGCTGCTATTGAACTTACA
GGGCTTGAAAATCCAAACAGTCCTACACAAATAAAAAAATGGATTGGCGAAAGGCTTGGAAGAGAGGTAAAGTCATTAAC
TAAAACAAGTATTCCAGGACTTATTGAAGAAGCTACGTCTTTAAATAAAAGTGAAGTTATAAAAATGTTAGAACTAAGGC
AACTAATGGCCAAAACTTCTATTAAGAAATATGACACAATGCAAAATGCAAGATGTAAAGATGGTAGAGTAAGAGGTTTA
TTACAATTCTATGGAGCTAATAGAACGGGGAGATGGGCAGGAAGATTAGTACAAGTTCAAAATCTACCTCAAAATCATTT
ACCGGATCTAGACAACGCTAGGAATTTTGTTAGAGAGGGAAAATTTCAGGAAGTAGAATTTTTATTTGATAGTGTTCCAG
ATACATTAAGCCAATTAATAAGAACAGCTTTTATACCTAGAGAAGGTAATAGATTTATAGTATCAGATTTTAGTGCTATA
GAAGCTAGGGTTATCGCTTGGTTTGCTGGAGAGCAATGGAGATTAGATGTTTTTAGTACACATGGGAAAATATATGAAGC
TTCAGCTAGTCAAATGTTTAAGGTAGCTATAGAAAGTATAAAAAAGGGTTCAGAGTTAAGGCAAAAAGGAAAAATAGCAG
AATTGGCACTTGGGTATGGTGGAAGTGTTGGAGCTCTTAGTTCAATGGATAGAAAAAAAAGTATTCCAGAAGAAGAACTT
CCTGGACTAGTTAAAAGTTGGAGAAATGCTAATCCTAATATAACTAAATTTTGGTGGGATGTAGATAAGGCTGCTAAGAA
AGTTATAAGAGAAAGAACTACGGTGAACTTACAATACGGACTTAAATTTATATATGATCCAGGAGTTTTATTTATACAAT
TGCCTAGTGGAAGAAAGCTAAGTTATATAAGGCCAAAGATAGAACCGCATGAAACCTTTAGTGGGGATAAAATCACCTAT
GAAGGTATGGAACAAACGTCTAAACAATGGAAAAGAATAGATACTTATGGCCCTAAACTAGTGGAGAATATAGTACAAGC
TACATCTAGAGATTGTTTAAGAGAAGCTATGTTTAGAGTAGATAAAGCAGGATATGACATAGTAATGCATGTGCATGATG
AAGTTGTATTGGATATACCAAAAGATAGGGCTACAGTTAAAGAAATAAATGAATTAATGGGCCAGCCTATAGAATGGGCT
CCGGGATTACCTTTGAAAGCTGATGGATATGAATGCAATTATTACCAAAAGGATTAG

Protein sequence :
MVIFIDTLSIDVETYSSMDIKTSGAYKYCESPDFEILLFAYAFNDEPVQIVDLANGEKLPSNVFYALTDPNIIKTAFNAN
FERNSIKNQYPALCPPEQWECTMVKALTLGLPSSLDMVGKALKFEEDKQKMKEGKALIQYFCKPCKPTKTNGKRTRNLPE
HDMEKWETFKEYCKRDVEVEREIRNLLNRYETKVEEQKLWQLDQHINDRGIGTDLILIKQAIECDTNYTERLTKAAIELT
GLENPNSPTQIKKWIGERLGREVKSLTKTSIPGLIEEATSLNKSEVIKMLELRQLMAKTSIKKYDTMQNARCKDGRVRGL
LQFYGANRTGRWAGRLVQVQNLPQNHLPDLDNARNFVREGKFQEVEFLFDSVPDTLSQLIRTAFIPREGNRFIVSDFSAI
EARVIAWFAGEQWRLDVFSTHGKIYEASASQMFKVAIESIKKGSELRQKGKIAELALGYGGSVGALSSMDRKKSIPEEEL
PGLVKSWRNANPNITKFWWDVDKAAKKVIRERTTVNLQYGLKFIYDPGVLFIQLPSGRKLSYIRPKIEPHETFSGDKITY
EGMEQTSKQWKRIDTYGPKLVENIVQATSRDCLREAMFRVDKAGYDIVMHVHDEVVLDIPKDRATVKEINELMGQPIEWA
PGLPLKADGYECNYYQKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 1e-148 52
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 2e-155 49
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 3e-155 49