Gene Information

Name : serS-1 (CLI_0026)
Accession : YP_001389385.1
Strain : Clostridium botulinum Langeland
Genome accession: NC_009699
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 22267 - 23547 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAAATAATTCAAATGAAATAAAAGAAGCATTAAACAATAGAGGAGAAAAGTTTGATGT
AACTGTAATTGATGAAGTTTTAAAATTAGATGAAGAAAGAAGAAATATTTTAGCTAAAGTTGAGGTTTTAAAAAGTAAGA
GAAATCAAGTTTCTTCTGAAGTTCCTAAATTAAAAAAAGAAGGAAAAGATGTATCTAATATAGTAGCTGAAATGAAGAAT
TTATCAGAAGAGATAAAAGGATTTGATGCTACTTTAGCTAAAATAGATGAAAAAATACAATATATAATGCTTAGAATACC
TAATATACCAAACCCACAAGTTCCAGATGGAGAAACAGATGAGGATAATATAGAAATAAGAAATTGGCTAGAACCAACAA
AATTTTATTTTGAACCTAAAGCACATTGGGATATAGGAACAAATTTAAATATTCTTGATTTTGAAAGAGCTGGAAAAGTA
ACAGGATCAAGATTTACTTTTTATAAAGGATTAGGGGCTAGATTAGAAAGAGCAGTAATATCTTATTTTTTAGATACTCA
TACAGAAAAACATGGTTATACTGAAATATTACCACCTTATATGGTAAATAGAACAAGTATGATAGGAACAGGACAATTAC
CTAAATTTGAAGAAGACGCTTTTAAAATTTCAGAGGATGATTACTTTTTAATACCAACTGCAGAAGTTCCTGTAACTAAT
TTATATAGAGATGAAATCTTAAAAGGTGATGAATTACCATTAAAACATGTAGCTTATAGTGCTTGTTTTAGATCAGAAGC
AGGTTCAGCAGGTAGAGATACAAGAGGTCTTGTTAGACAACACCAATTTAATAAAGTAGAGCTTGTTAAATTTACAAAAC
CAGAACAGTCTTATGAAGAATTAGAAAAATTAACTAATGATGCTGAAACAGTATTAAAAGAGTTAGGTATTCCATATAGA
GTTGTAAGAATATGCAAAGGTGATTTAGGATTTACAGCTGCATTAAAATATGATTTAGAAGTTTGGATGCCAAGTTACAA
TAGATATGTTGAAATATCAAGCTGTAGTAACTTTGAAGACTTTCAAGCAAGACGTGCTAATATAAGATACAAAGAAGATG
CAAAAGCAAAACCACAATATGTTCATACATTAAATGGATCAGGAGTTGCTATTGGAAGAACTGTTGCAGCTATACTTGAA
AACTATCAAAGTGAAGATGGATCAGTTACAATACCAGAAGTGTTAAGACCTTATATGGGAGGAAGAGAAGTAATAAAATA
A

Protein sequence :
MLDLKRIRNNSNEIKEALNNRGEKFDVTVIDEVLKLDEERRNILAKVEVLKSKRNQVSSEVPKLKKEGKDVSNIVAEMKN
LSEEIKGFDATLAKIDEKIQYIMLRIPNIPNPQVPDGETDEDNIEIRNWLEPTKFYFEPKAHWDIGTNLNILDFERAGKV
TGSRFTFYKGLGARLERAVISYFLDTHTEKHGYTEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTN
LYRDEILKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYEELEKLTNDAETVLKELGIPYR
VVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDAKAKPQYVHTLNGSGVAIGRTVAAILE
NYQSEDGSVTIPEVLRPYMGGREVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-127 61