Gene Information

Name : clpB (CLC_0449)
Accession : YP_001386344.1
Strain : Clostridium botulinum Hall
Genome accession: NC_009698
Putative virulence/resistance : Virulence
Product : clpB protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 444793 - 447393 bp
Length : 2601 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGAATATTGAAAAATTAACTTTAAAGGTACAGCAAGCTATAAATGATTCTCAACTTGTTGCAGTTAAGTATAATCATCA
GCAGATTGATACTATACATTTATTTTCAGCCTTAATTTCTCAAGATGATGGATTAATTCCTAATATTTTAGGGAAAATGG
GAGTGAATATAAGAGATATTAATGCTGAAACCAATAGGGTCTTAGATAATATGCCTAAAGTATTAGGTGAGGGAGCACAG
TCATCTTCTGTGTATCCTACTAGAAGGTTTGAAGAGGTTTTTGTAAGGGCAGAACAGATAGCAAAGGATTTTAAAGATTC
ATATATAAGTGTAGAACATGTTTTATTAGCAATAATGGATGTGGATAGAAATACTGTTCTTCCTATATTAGAAAAATTTG
GAGTAAAAAAATCAGAGTTTTTAAAGGCATTATCAGCTGTTAGAGGAAGTCAAAGAGTTGATAATCAAGATCCAGAGGGG
ACTTATGAAGCTTTGGTTAAGTATGGTAGAAATTTAGTTGAAGAAGCTAAGAAACATAAATTGGATCCTGTTATAGGTAG
AGATGAAGAAATAAGAAGAGTTGTAAGAATTTTATCTAGAAGAACTAAGAATAATCCTGTTCTTATTGGAGAACCAGGTG
TAGGTAAGACTGCTATTGTAGAGGGATTAGCAGAGAGAATTGTTAGAGGAGATGTACCAGAAAGTTTAAAAAATAAAATA
ATATTTTCTCTAGATATGGGAGCACTTATTGCAGGTGCAAAATATAGAGGAGAATTTGAAGAAAGATTAAAAGCAGTATT
AAAAGAAGTTCAAAATAGTGAAGGAAGAATAATTTTATTTATAGATGAAATTCATACTATAGTAGGGGCAGGAAAAACAG
AGGGTTCTATGGATGCAGGAAATTTAATAAAACCTATGCTTGCCAGAGGAGAACTTCATTGTATTGGAGCTACTACCTTT
GATGAATATAGACAGTATATAGAAAAAGACAAAGCTTTAGAAAGAAGATTTCAACCTGTAATAACAGATGAGCCTACAGT
AGAGGATACAGTATCTATATTAAGAGGGCTTAAAGAAAGATTTGAAATATATCATGGAATAAGAATACATGATTCAGCTA
TTGTAGCTGCAGCTAAGCTCTCTAGTAGATATATTACAGATAGATATCTCCCAGACAAAGCAATAGATTTAATAGATGAA
GCTTGTGCTATGATAAGAACAGATATAGATAGTATGCCAACGGAAATGGATTCAATGAAAAGAAAAATATTTCAATTAGA
AATAGAAAAGGAAGCATTGTCTAAAGAAAAAGATGTGGCTTCAAAGGAAAGATTAGAAGTTTTAGAAAAGGAATTGAGTG
AACTAAAAGAGAAAGATAAAGAAATGACAGCCAAGTATGAAAATGAAAAATCTCATATAACAAAAATAAGAGATTTAAAA
GAAAAATTGGATGATGTTAGAGGTCAGATGGAAAAAGCCGAAAGAGAATATGATTTGAATAAAGTTGCAGAATTAAAATA
TGGTTTAATACCAGCTCTTCAAAGAGAAATAGAAGAAAAAGAAAAATTAATAAAGGAAAATAGTAACGGAAATGCTATGT
TAAAAGAAGAGGTTACAGAGCAAGAAATTTCTGAAATAATCTCTAAATGGACTGGTATACCTGTAACAAGATTAGTTGAA
ACTGAAAGACAAAAACTATTACAATTAGGAGATCAATTAGAAACTAGAGTAATAGGTCAAGGAGAGGCAGTAAAAGCAGT
AACTAATGCAGTTATAAGAGCTAGAGCAGGACTAAAAGATCCAAGAAAACCTATAGGATCATTTATATTCTTAGGACCTA
CAGGTGTAGGAAAGACAGAACTTGCAAAAACTTTGGCCAGAACTTTATTTGATACTGAAGAAAATATTATAAGAATAGAT
ATGTCTGAATATATGGAAAAATATTCAGTATCAAGACTTATAGGAGCTCCTCCAGGATATGTAGGATATGAAGAAGGAGG
CCAGCTAACAGAAGCCGTTAGGAGAAAACCTTATAGTGTTATATTATTTGATGAAATAGAAAAAGCTCATGATGACGTAT
TTAATATATTCCTTCAAATATTAGATGATGGAAGACTTACGGACAATAAAGGGAAGGTTATAGATTTTAAAAATACTATA
ATTATAATGACTTCTAATTTGGGAAGTAACTATTTATTAGATAATGAAAGCAAAGAAGGTATAGATGAAAGTATAAGAAC
AAGAGTAAAAGAGGCTTTAAAGGCTAGATTTAAACCAGAATTTTTAAATAGAGTAGATGACATTATAATGTTTAAACCTC
TTACGGTAGAAGACATTAAGAGAATAATAGATATATTCTTAGATGATATAAGAAAAAGACTTAAAGATAAGAATATACAG
CTTAAAATTACTGATAGTGCAAAAGATATAATGGCCAAAGAAGGTTATGATCCAATATATGGCGCAAGGCCGCTAAAGAG
ATATATAGAAGATACTATAGAAACAGAAATAGCAAAACAAATAATAGCAGGTAATATATATGAAGGTACTACTGTAGGAG
TAGACTTAAAAGGAGAGTCAATAGTTATAGAAAGAATATAA

Protein sequence :
MNIEKLTLKVQQAINDSQLVAVKYNHQQIDTIHLFSALISQDDGLIPNILGKMGVNIRDINAETNRVLDNMPKVLGEGAQ
SSSVYPTRRFEEVFVRAEQIAKDFKDSYISVEHVLLAIMDVDRNTVLPILEKFGVKKSEFLKALSAVRGSQRVDNQDPEG
TYEALVKYGRNLVEEAKKHKLDPVIGRDEEIRRVVRILSRRTKNNPVLIGEPGVGKTAIVEGLAERIVRGDVPESLKNKI
IFSLDMGALIAGAKYRGEFEERLKAVLKEVQNSEGRIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELHCIGATTF
DEYRQYIEKDKALERRFQPVITDEPTVEDTVSILRGLKERFEIYHGIRIHDSAIVAAAKLSSRYITDRYLPDKAIDLIDE
ACAMIRTDIDSMPTEMDSMKRKIFQLEIEKEALSKEKDVASKERLEVLEKELSELKEKDKEMTAKYENEKSHITKIRDLK
EKLDDVRGQMEKAEREYDLNKVAELKYGLIPALQREIEEKEKLIKENSNGNAMLKEEVTEQEISEIISKWTGIPVTRLVE
TERQKLLQLGDQLETRVIGQGEAVKAVTNAVIRARAGLKDPRKPIGSFIFLGPTGVGKTELAKTLARTLFDTEENIIRID
MSEYMEKYSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILFDEIEKAHDDVFNIFLQILDDGRLTDNKGKVIDFKNTI
IIMTSNLGSNYLLDNESKEGIDESIRTRVKEALKARFKPEFLNRVDDIIMFKPLTVEDIKRIIDIFLDDIRKRLKDKNIQ
LKITDSAKDIMAKEGYDPIYGARPLKRYIEDTIETEIAKQIIAGNIYEGTTVGVDLKGESIVIERI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-159 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_001386344.1 clpB protein VFG2084 Protein 4e-103 41