Gene Information

Name : secA (CLC_0227)
Accession : YP_001386130.1
Strain : Clostridium botulinum Hall
Genome accession: NC_009698
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 200058 - 202565 bp
Length : 2508 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGGAATTTTAAATAAAATATTTGGTACATATAGTGAAAGAGAACTTAGAAGAGTTAACCCTATAGTAAACAAAATAGA
AGCTTTAGATGAAAAAATGCAATCCTTAAAAGATGAAGATTTTAAGCTAAAAACTGAAGAATTTAAAAGTAGATTAGAAA
AAGGGGAAAAACTAGATGATATTTTACCAGAAGCTTTTGCCTTAGTTAGAGAAGCGGCACATAGAACCATAGGACTTAAA
CATTATAGAGAACAATTAATAGGCGGTGTAGTATTACACCAAGGAAGAATTGGAGAAATGAAAACCGGTGAAGGTAAAAC
TTTAGTTGCTACATTGCCAGCCTATGTAAATGCATTAACAGGAAAAGGGGTACATATAGTTACAGTTAATGATTACTTGG
CAAAAAGAGATAGGGATTTAATGGCTCCGGTATATGAATTTTTAGGGCTAAAAGTAGGAGTTATTTTGCATAATTTAAAT
AATGAAGAAAGACAAGAAGCTTATGGTTCAGATATAACTTATGGAACAAATAGTGAATTTGGCTTTGATTATTTAAGAGA
TAATATGGTAGTTTATAAAGAAGAAAGAGTTCAAAGAAAGTTAAACTTTTCAATTGTGGATGAAGTGGACTCTATATTAA
TAGATGAAGCTAGAACTCCATTAATAATATCAGGTCAAGGGGAGAAGTCTACAGAGTTTTATAAGGTTGCAGATTATTTC
ACTAAATCTCTAATAGCTGAAAAAGATTTTACAATAGATGAAAAAGCTAATTCAGCTATGCTTACAGATGAAGGTGTTAA
TAAAGCAGAGAATTTCTTTAAAGTAGATAACTATGCTGATGCAGAAAACATGGAAATACAACACCATGTAGTTCAAGCTT
TAAAAGCTAACTATGTAATGAAAAAAGATAAAGATTATATGATTAAGGATGGAGAAATTCTAATAGTTGATGAGTTTACA
GGAAGAGCTATGGAAGGAAGAAGATATAGCGATGGATTGCACCAAGCTATAGAAGCTAAAGAAGGCGTTAGAGTAGAAAG
AGAATCTAAAACCTTAGCTACAATAACTTATCAAAACTATTTTAGAATGTACAATAAATTGTCTGGTATGACAGGAACTG
CTCAAACAGAAGAAAATGAATTTAGAGAAATCTATGGATTAGATGTAATTGTAATACCTACACATGAGCCTATAGCAAGA
ATAGATAATGCTGATGTAGTATATAAATCAGAAAAGGGTAAATTTAAAGCCATAGTTGATGAAATAGTAGAAAGATATAA
AAAAGGTCAACCAATGCTAGTAGGTACGGTAAGCATAGAAAAATCAGAAATGTTATCCTCTATGTTAAAGAAAAAAGGAG
TACCTCATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCGGAAATAATATCTCATGCAGGGGAATATGGGATGGTT
ACAATAGCCACTAATATGGCAGGCCGTGGTACAGATATAAAGCTTACTAAGGAAGCTGAAGAAGCAGGCGGGCTTATGAT
TATAGGTACAGAAAGACATGAGTCTAGAAGAATAGACAACCAATTAAGAGGACGTTCTGGTCGTCAAGGAGATCCTGGTG
AATCAAGATTTTTTGTATCTTTAGAAGATGATTTAATGAGAATATTTGGTTCAGAAAGAATACAAGGAATAGTTGATAAA
TTAGGACTGGCTGAAGATGAAGCTATAGAAAGTAAAATGGTAAGTTCAGCTATAGAAAGTGCTCAAAAGAAGGTAGAAGG
AAATAACTTTGATATAAGAAAAACTTTATTACAATATGATGATGTAATAAATAAACAAAGAGAAATAATCTATAAACAAA
GAAGTGAGGTTTTAGAGGGAGAAGACTTAAAGGATCAAATAAGAGATATGATAAGGGATGTGGTTTATACTGCAGTAAAT
TCTCATATTTCAGGAGTAGAAGAAGAGTTTCAAACAGAACTTCAAAATCTTGTTAATTATTTAGAAGACATATGCTTACC
AAAGGCCTTAGTAAAGGTAAAAGATATAAGTAATTTATCAGATGAAGAAATAAAAGAAAAATTATTAGAAGCAGTAGAGA
ATATATATATCCGCAAAGAAAAAGAAATTGGGGAAGAACAAATAAGAGAAATAGAAAGAGTAATATTACTTAGGGTTGTA
GATACTAAATGGATGGATCATATAGATGATATGGATCACTTAAAACAAGGTATAGGACTAAGAGCATATAGACAACAAGA
TCCAGTTCAAGCGTATCAATTTGAAGGTAGTGAAATGTTTGAGGAAATGATCTATAACATTAAAGTAGATACAGTAAGAT
ATTTATTCCATGTAGAAGTAGAAAAAGCACCTGAAAGAGAGAAAGTTGCAAAAGAAACATCAACTAATTATGATGAAGAT
TCAGTAAAAAAACAACCTATAAAAAAGGAAAATAGAATAGGTAGAAATGATATGTGTCCTTGCGGAAGTGGGAAAAAATA
TAAAAATTGTTGTGGTAGAATGGCATAA

Protein sequence :
MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK
HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN
NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT
GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR
IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV
TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK
LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN
SHISGVEEEFQTELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVV
DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED
SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 3e-121 41