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Name : pykA (CLB_3428) Accession : YP_001385689.1 Strain : Clostridium botulinum ATCC 19397 Genome accession: NC_009697 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 3581619 - 3583376 bp Length : 1758 bp Strand : - Note : identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064 DNA sequence : ATGCAAAAGACTAAAATGATATTTACAATAGGTCCTGCAAGCTCGACAGAAGAAATTGTATCAAAATTAATAGAAGCTGG AATGAGTGTATCAAGACACAATTTTTCTCACGGATCACATCCAGAACACAAAGAAAGAATGATGATGATTAAGAAATTAA GAGAAAAACATAACAAACACATAGCTATTATGTTAGACACCAAAGGACCAGAAATAAGAACAGGTAATTTTTCAGTGGAT AAAGTGGAATTAAAAGAAGGGGCAGAGTTTACAATATATTGTAGAGAAGACATAGTAGGTGATGAAACAAAATGTTCTAT TACTTATGATGAACTATATAAAGATGTAGTTAAAGGAAATAAAATACTGATAGATGATGGATTAGTAGAGCTAGAGGTTC AGTCAGTAGAAGATAATAAAATCCATACAGTAGTTAAAAATTCAGGAACTGTTTCAAATCATAAGGGAGTAAATGTTCCA GGAGTTTCAGTATCACTTCCAGCAGTTACTGAAAAAGATATAGAAGATTTAAAATTTGGATGTGAAGTAGGAGTAGATTT AATAAGTGCATCTTTTATAAGAAAAGCCTCTGATGTATTAGCTATAAGAAAAATATTGGAAGAAAATGGTGGAAATGAAA TACAGATAATCTCTAAGATAGAAAATCAAGAGGGCGTTGACAATATAGATGAAATAATAAAATTTTCTGATGGAATAATG GTAGCTAGAGGAGATATGGGAGTCGAAATTCCTATAGAAGAAGTTCCAATAGTACAAAAAAGAATAATAGAAAAATGTAA TAAAGCAGGTAAGCCTGTAATTACAGCAACTCAAATGTTAGATTCTATGATGAGAAACCCTAGACCAACAAGAGCTGAAG CCTCAGACATAGCCAATGCAATATTTGATGGAACAGACGCCATAATGTTAAGCGGAGAATCAGCAAATGGAAAATATCCG GTAGAAGCTGCAAGAACTATGTCTAGAATAGCTAAAACAGCAGAAGCAAAATTAAATTATGATGCTATATTAAATAAAAT GAGAGAAAGTCATATATTAAATGTTCCTAATGCTATAAGCTTATCAGCGTGTACTACAGCATCAGAATTAAATGCTACAG CTATAATCACAGCAACTCAAAGTGGGCATACTGCAAAAATGGTATCAAAATATAGACCACAATGCCCTATTATAGCAGTA ACACCAAATGAAATAGTTGCTAGAAAGTTAGCATTAAATTGTGGAGTAGTACCACTATTAACGGAAACATTTAATTCTAC AGATGAGCTTATAGATAAATCAGTTAATAAATCTTTAGAAGAAGGATATGTTAAAAATGGCGACTTAGTTGTTATAGCAG GAGGAATACCAGTGTCTTACTCAGGAACAACTAATATGTTAAAAGTTCACATAGTAGGAGATATCTTAGCCCAAGGAAGA GGTTCAGGAACTAGACCAACTTATGGGAATGTAAAGATAGTAAACAATCCTTCAGAAGCAGAAAATATAGTTGAAAGAGA TGACATATTAGTAGTTAAAAATTTAGATAGAAGATATATGACTATTTTAGATAGAGTATCAGGCATAGTGGCTGAAGAAG GTGGAATAACATCACACTTAGCTATAGAATGCATAGCAAGGGATATTCCATTTATATGTAATGCAGGTGGAGCTATGGAT ATTTTAAAAACAGGAACATATGTAACACTTGATACAGTAAGAGGAATAGTATACAACGGAAGAGCTAATATAGTTTAA Protein sequence : MQKTKMIFTIGPASSTEEIVSKLIEAGMSVSRHNFSHGSHPEHKERMMMIKKLREKHNKHIAIMLDTKGPEIRTGNFSVD KVELKEGAEFTIYCREDIVGDETKCSITYDELYKDVVKGNKILIDDGLVELEVQSVEDNKIHTVVKNSGTVSNHKGVNVP GVSVSLPAVTEKDIEDLKFGCEVGVDLISASFIRKASDVLAIRKILEENGGNEIQIISKIENQEGVDNIDEIIKFSDGIM VARGDMGVEIPIEEVPIVQKRIIEKCNKAGKPVITATQMLDSMMRNPRPTRAEASDIANAIFDGTDAIMLSGESANGKYP VEAARTMSRIAKTAEAKLNYDAILNKMRESHILNVPNAISLSACTTASELNATAIITATQSGHTAKMVSKYRPQCPIIAV TPNEIVARKLALNCGVVPLLTETFNSTDELIDKSVNKSLEEGYVKNGDLVVIAGGIPVSYSGTTNMLKVHIVGDILAQGR GSGTRPTYGNVKIVNNPSEAENIVERDDILVVKNLDRRYMTILDRVSGIVAEEGGITSHLAIECIARDIPFICNAGGAMD ILKTGTYVTLDTVRGIVYNGRANIV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-104 | 51 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-104 | 51 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-104 | 51 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 2e-103 | 51 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykA | YP_001385689.1 | pyruvate kinase | VFG0479 | Protein | 8e-105 | 51 |
