Gene Information

Name : smpB (CLB_0275)
Accession : YP_001382638.1
Strain : Clostridium botulinum ATCC 19397
Genome accession: NC_009697
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 270724 - 271194 bp
Length : 471 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGTAAAAAGAAGGGAAGCAATACTCTTGCAGAAAATAGAAAAGCAAGGCATGATTATTTTATAGAAGAAACTTACGA
AGCTGGTATAGAATTAGTAGGGACAGAGGTTAAATCTATAAGACAAGGAAAAGCAAACTTAAAAGATAGTTATGCTGAGA
TTAGAAATGGAGAAGTTTTTGTTAGAAACATGCATATAAGTCCCTATGAACAAGGAAACATATATAATAAAGATCCACTA
AGAGATAGAAAATTGTTACTTCATAAGAGTGAAATATATAAATTAGTAGGCTTTACAACTCAACAGGGGTATACCCTGAT
TCCTTTATCATTATATCTTAAACATGGAAGAGTAAAAGTTAGTTTAGCTGTAGCTAAGGGTAAGAAAAATTATGATAAGA
GAGATGCAATGCTAGAAAAGGCAGCAAAAAGAGAAATGGACAGACAAATTAAAGAAAGAAGTAGATATTAA

Protein sequence :
MSKKKGSNTLAENRKARHDYFIEETYEAGIELVGTEVKSIRQGKANLKDSYAEIRNGEVFVRNMHISPYEQGNIYNKDPL
RDRKLLLHKSEIYKLVGFTTQQGYTLIPLSLYLKHGRVKVSLAVAKGKKNYDKRDAMLEKAAKREMDRQIKERSRY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 8e-43 66
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 7e-33 52
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-30 50