Gene Information

Name : serS-1 (CLB_0022)
Accession : YP_001382425.1
Strain : Clostridium botulinum ATCC 19397
Genome accession: NC_009697
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 22357 - 23637 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAAATAATTCAAATGAAATAAAAGAATCATTAAACAATAGAGGAGAAAAGTTTGATGT
AACTGTAATTGATGAAGTCTTAAAATTAGATGAAGAAAGAAGAAATATTTTAGTTAAAGTTGAGGTTTTAAAAAGTAAGA
GAAATCAAGTTTCTTCTGAAGTTCCTAAACTAAAAAAAGAAGGAAAAGATGTATCTAATATAGTAGCTGAAATGAAAAAT
TTATCAGAAGAAATAAAAGGGTTTGATACTACTTTAGCTAAAATAGATGAAAAAATACAATATATAATGCTTAGAATACC
TAATATACCAAACCCACAAGTTCCAGATGGAGACACAGATGAGGATAATATAGAAATAAGAAATTGGTCAGAACCAACAA
AATTTGATTTTGAGCCTAAAGCACATTGGGATATAGGTTCAAATTTAAATATTCTTGATTTTGAAAGAGCTGGAAAAGTA
ACAGGATCAAGATTTACTTTTTATAAAGGATTAGGAGCTAGATTAGAAAGATCATTAATATCTTATTTTCTAGATACTCA
TACAGAGAAGCATGGCTACACTGAAATATTACCACCTTATATGGTGAATAGAACAAGTATGATAGGAACAGGACAATTAC
CTAAATTTGAAGAAGATGCTTTTAAAATTTCAGAGGATGATTACTTCTTAATACCAACTGCAGAGGTTCCTGTAACTAAT
TTATACAGAGATGAAATCTTAAAAGGTGATGAATTACCATTAAAACATGTAGCTTATAGTGCTTGTTTTAGATCAGAAGC
CGGTTCAGCAGGTAGAGATACAAGAGGTCTTGTTAGACAGCATCAATTCAATAAAGTAGAGCTTGTTAAATTTACAAAAC
CAGAACAGTCTTATGAAGAATTAGAAAAATTAACTAATGATGCTGAAACAGTATTAAAAGAGTTAGGTATTCCATATAGG
GTTGTAAGAATATGTAAAGGTGATTTAGGATTTACAGCTGCATTAAAATATGATTTAGAAGTTTGGATGCCAAGTTACAA
TAGATATGTTGAAATATCAAGCTGTAGTAACTTTGAAGACTTCCAAGCAAGACGTGCTAATATAAGATATAAAGAAGATG
CAAAAGCAAAACCACAATATGTTCATACATTAAATGGATCAGGAGTTGCTATTGGAAGAACTGTTGCAGCTATACTTGAA
AACTATCAAAATGAAGATGGATCAGTTACAATACCAGAAGTGTTAAGACCTTATATGGGAGGAAAAGAAGCAATAAAATA
G

Protein sequence :
MLDLKRIRNNSNEIKESLNNRGEKFDVTVIDEVLKLDEERRNILVKVEVLKSKRNQVSSEVPKLKKEGKDVSNIVAEMKN
LSEEIKGFDTTLAKIDEKIQYIMLRIPNIPNPQVPDGDTDEDNIEIRNWSEPTKFDFEPKAHWDIGSNLNILDFERAGKV
TGSRFTFYKGLGARLERSLISYFLDTHTEKHGYTEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTN
LYRDEILKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYEELEKLTNDAETVLKELGIPYR
VVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDAKAKPQYVHTLNGSGVAIGRTVAAILE
NYQNEDGSVTIPEVLRPYMGGKEAIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-129 61