Gene Information

Name : guaA (Anae109_1525)
Accession : YP_001378715.1
Strain : Anaeromyxobacter sp. Fw109-5
Genome accession: NC_009675
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1728938 - 1730494 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGGACATCCACGCAGAGAAGATCCTCATCCTCGACTTCGGCTCGCAGTACACGCAGCTCATCGCGCGGCGGCTGCGGGA
GCTCGGCGTCTACTGCGAGATCCACCCCTGCACGATGACGCCCGAGGCGATGCGCGCGTTCGCGCCGCGGGGCGTCGTGC
TCTCCGGCGGCCCGGCGTCGGTGCTGGCCGAGGGGAGCCCGCGCGCCGACCGGCTCGTCTTCGAGCTCGGCGTCCCGGTG
CTCGGCATCTGCTACGGCCTGCAGCTCCTCGCGCACGAGCTGGGCGGGCGGGTGGACAAGGCCGCCCACCGCGAGTACGG
GCCCGCGACCATCGAGACGCGGGAGGACGCGGAGCTGTTCGAGGGCCTGCCGCGGCGGCTCGACGTCTGGATGAGCCACG
GCGACCGCGTGGAGAAGCTGCCGCCGGGCTTCGAGCCCATCGCCTCCACTCCGTCCGCGCCCTTCGCCGCGGTCGAGGAC
CGCCGCCGCCGCTTCTTCGGCGTGCAGTTCCACCCGGAGGTGGTCCACACGCCGCTCGGCAAGGACGTCCTCCGGAACTT
CGCCTACCGCGTGTGCGGCTGCTCCGGCAGCTGGTCGATGCGCGCCTACGCCGAGATCGCCGTGGAGCAGATCCGCGCCC
AGGTGAAGGACGGGCACGTCATCTGCGCCCTCTCCGGCGGGGTGGACTCCGCCGTCGCGGCGCTGCTCGTCCACCGCGCC
ATCGGGGACCGGCTGCGCTGCATCTTCGTGGACAACGGGGTGCTGCGCGCCGGGGAGCGCGCCCAGGTCGAGGAGGTCTT
CGGCGGCATGTTCCACCTGCCCCTCGTGACCGTGGACGCCTCCGCGCGCTTCCTCGCGAGGCTCGCGGGCGTCACCGATC
CCGAGCAGAAGCGGAAGATCATCGGCCGCGAGTTCATCGCCGTCTTCGAGGAGCAGGTGGAGGACCTCGCCGCGCACGGC
GAGCGCGCCCAGTTCCTGGTGCAGGGCACGCTCTACCCCGACGTCATCGAGTCCGTCTCCTTCAAGGGCCCCTCCGCCAC
CATCAAGAGCCACCACAACGTCGGCGGCCTGCCCGAGGTGATGAAGCTCGGCCTCGTGGAGCCCCTGCGGGAGCTCTTCA
AGGACGAGGTGCGCCGGCTCGGCCTCGAGCTCGGGCTGCCCCAGCACATCGTGCAGCGCCAGCCGTTCCCCGGCCCGGGG
CTCGCCATCCGCGTGCTCGGCGAGGTCACCGAGGAGCGGCTCGCCCTGCTCCGCAAGGCCGACACGATCGTGCAGGAGGA
GATCCGCGCCGCCGGGCTCTACGAGAAGCTCTGGCAGGCGTTCGCCGTGCTCCTCCCGGTGCGGAGCGTCGGCGTCATGG
GCGACGAGCGCACCTACGAGGCCACGTGCGCCGTCCGCGCCATCGAGTCCACCGACGGGATGACCGGGGACTGGGCGCGC
CTGCCGTACGAGCTCCTCGGCCGGATGTCGTCGCGCATCATCAACGAGGTCCGCGGCATCAACCGCGTGGTGTACGACAT
CTCTTCCAAGCCGCCCGCCACCATCGAGTGGGAGTAG

Protein sequence :
MDIHAEKILILDFGSQYTQLIARRLRELGVYCEIHPCTMTPEAMRAFAPRGVVLSGGPASVLAEGSPRADRLVFELGVPV
LGICYGLQLLAHELGGRVDKAAHREYGPATIETREDAELFEGLPRRLDVWMSHGDRVEKLPPGFEPIASTPSAPFAAVED
RRRRFFGVQFHPEVVHTPLGKDVLRNFAYRVCGCSGSWSMRAYAEIAVEQIRAQVKDGHVICALSGGVDSAVAALLVHRA
IGDRLRCIFVDNGVLRAGERAQVEEVFGGMFHLPLVTVDASARFLARLAGVTDPEQKRKIIGREFIAVFEEQVEDLAAHG
ERAQFLVQGTLYPDVIESVSFKGPSATIKSHHNVGGLPEVMKLGLVEPLRELFKDEVRRLGLELGLPQHIVQRQPFPGPG
LAIRVLGEVTEERLALLRKADTIVQEEIRAAGLYEKLWQAFAVLLPVRSVGVMGDERTYEATCAVRAIESTDGMTGDWAR
LPYELLGRMSSRIINEVRGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-151 57
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-151 57
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-151 57
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-129 55