Gene Information

Name : Bcer98_0397 (Bcer98_0397)
Accession : YP_001373748.1
Strain : Bacillus cytotoxicus NVH 391-98
Genome accession: NC_009674
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 451640 - 453565 bp
Length : 1926 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: bca:BC

DNA sequence :
ATGAACTCAGAAGTAAAAACATTACCACCAACAAAAAATGTATCTCCCTTATCTTGGTTGAAAACATTGCAAGACCATTA
TGAACTCATCTTTGCAATCCTATCAGGTATTTTCATTTTAACTGGCTGGTTATTCACAAAAAATGAAATGGCAACAGTTG
GCGTAACCTTTTACATTTTAGCCTATATAATTGGAGGGTATGCCAAAGCAAAGGAAGGCATTGAAGATACGATTGCTGAG
AAGGAATTAAATGTAGAAATGTTAATGCTCTTTGCTGCTATCGGCGCTGCTATTATTGGATACTGGACAGAGGGCGCTAT
CCTCATATTTATATTTGCCTTAAGTGGTGCTTTGGAATCTTACACGTTAAACAAAAGTCACAAAGAAATTTCAGCACTTT
TGGACTTACAACCTGAGGAAGCCTTGCGCATTTCAAATGGCAACGAAGAACGCATTCCTGTGGAACAATTACAAGTGAAT
GATACGATCTTAATTAAGCCGGGTGAGCGCGTTCCTGCTGATGGCATCATCCATAAAGGTGAGACCAATATTGATGAGGC
AGCGATTACTGGTGAACCAATTCCAAATGAAAAAAAATTGGGTGATGAAGTATTTGCGGGAACTGTCAATTTACGTGGTG
CAATTGAAGTAAATATTACAAAACGTAGCGATCAAACATTGTTCCAAAAAATCATCCGCCTCGTTCAAAATGCACAAAGT
GAAAAATCACCGTCACAACTATTTATTGAAAAATTTGAAGGAACATATGTAAAAGGCGTATTGTTTATTGTTGCTCTTAT
GATGTTTGTTCCTCACTTTTTATTAGATTGGAGCTGGAATGAAACATTTTATCGTGCAATGATTTTACTTGTCGTTGCCT
CTCCTTGTGCGCTTGTTGCTGCTATTACACCAGCAACTTTATCAGCAATCTCTAATGGTGCAAGAAACGGTATTTTGTTT
AAAGGTGGTATTCATTTAGAACGCCTTGCTTCTGTTAAAGCAATTGCTTTTGACAAAACAGGAACATTAACACAAGGTAA
GCCAATCGTCACCGACATATATGTGCGCGAAGGAATAGCAAAAAAAGAATTGCTTTCTATCATAGCAGCAATTGAAAGTC
ATTCTACCCATCCTTTAGCAGAAGCAATTGTTAAATATGCTAAACAAACATATGACATTACACTCTACAAACCAGAAAAT
GTAGAAGATGTCACTGGATTTGGATTAAAAGGAATAGTGGCAAACAAAGCTTATAAAATCGGAAAAGCAGATTTTATAGG
TGAAGATACAAAAACATTCCATAACGGTATTTCTACTATACTGGAACAAGAAGGTAAAACGGTTGTCTATATTCGTGATG
ATGAATGCATTCTTGGACTTATTGCTTTAAAAGATACGCTTCGACAAGAAACAATTGCAGCTATTCGTGATTTACAAAGC
ATTGGTGTGGAAGCCATTATGATTACTGGAGATCATGAACAAACAGCTAAGGCGATCGCAACAGAAAGTAATATAAAAGA
GTATTACGCATCCTGTTTACCGGAAACGAAAGTAGAAACAGTGAAACAACTAAAAGAAAAATATGGAACCGTAGCAATGG
TTGGAGATGGCATTAATGATGCTCCTGCATTAGCGACTGCCAGCATTGGAGTGGCAATGGGAGAAGGAACAGATGTCGCT
TTAGAAACTGCCGACGTAGTTCTCATGAAAAATGAATTATCTCGTCTCGCTCAAGCCATCCGGTTATCAAAACGAATGAA
TCGTATTGTAAAACAAAACGTTATCTTTTCTTTAACCGTCATTGCTATGCTTATTTGCTCTAACTTTTTACAACTTTTAG
CTCTTCCATTCGGCGTAATCGGGCATGAAGGAAGTACCATTCTCGTCATCCTTAATGGCTTACGATTATTAAAAGGCAAT
AAATAA

Protein sequence :
MNSEVKTLPPTKNVSPLSWLKTLQDHYELIFAILSGIFILTGWLFTKNEMATVGVTFYILAYIIGGYAKAKEGIEDTIAE
KELNVEMLMLFAAIGAAIIGYWTEGAILIFIFALSGALESYTLNKSHKEISALLDLQPEEALRISNGNEERIPVEQLQVN
DTILIKPGERVPADGIIHKGETNIDEAAITGEPIPNEKKLGDEVFAGTVNLRGAIEVNITKRSDQTLFQKIIRLVQNAQS
EKSPSQLFIEKFEGTYVKGVLFIVALMMFVPHFLLDWSWNETFYRAMILLVVASPCALVAAITPATLSAISNGARNGILF
KGGIHLERLASVKAIAFDKTGTLTQGKPIVTDIYVREGIAKKELLSIIAAIESHSTHPLAEAIVKYAKQTYDITLYKPEN
VEDVTGFGLKGIVANKAYKIGKADFIGEDTKTFHNGISTILEQEGKTVVYIRDDECILGLIALKDTLRQETIAAIRDLQS
IGVEAIMITGDHEQTAKAIATESNIKEYYASCLPETKVETVKQLKEKYGTVAMVGDGINDAPALATASIGVAMGEGTDVA
LETADVVLMKNELSRLAQAIRLSKRMNRIVKQNVIFSLTVIAMLICSNFLQLLALPFGVIGHEGSTILVILNGLRLLKGN
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 5e-110 42
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 4e-110 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-104 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-104 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcer98_0397 YP_001373748.1 heavy metal translocating P-type ATPase BAC0092 Protein 3e-135 48
Bcer98_0397 YP_001373748.1 heavy metal translocating P-type ATPase BAC0124 Protein 5e-94 41